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[PDF] Top 20 Thermodynamics of the DNA damage repair steps of human 8-oxoguanine DNA glycosylase.

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Thermodynamics of the DNA damage repair steps of human 8-oxoguanine DNA glycosylase.

Thermodynamics of the DNA damage repair steps of human 8-oxoguanine DNA glycosylase.

... in the previous studies we investigated the conformational dynamics of hOGG1 and DNA substrates during the catalytic cycles using fluorescence detection ...[14,20]. The enzyme ... See full document

9

Estudos de reparo de DNA por excisão de nucleotídeos em lesões oxidativas em células...

Estudos de reparo de DNA por excisão de nucleotídeos em lesões oxidativas em células...

... excision repair (NER) mechanism is well known to be involved in the removal of UV-induced ...However, the participation of this repair mechanism in oxidative DNA lesions ... See full document

41

Use of the Comet Assay to study the role of MGMT, MMR and p53 in the repair of alkylating DNA damage

Use of the Comet Assay to study the role of MGMT, MMR and p53 in the repair of alkylating DNA damage

... In the organism, the most versatile mechanism of DNA repair is the nucleotide excision repair (NER), which can identify and repair several DNA ...damages, ... See full document

99

Age-related Changes in DNA Methylation Status of hTERT Gene Promoter of Oral Epithelial Cells

Age-related Changes in DNA Methylation Status of hTERT Gene Promoter of Oral Epithelial Cells

... purpose of this study was to investigate the effect of aging on the DNA methylation status of two genes involved in tumorigenesis (telomerase gene hTERT and DNA ... See full document

8

Effects of UV radiation exposure on DNA and DNA repair enzymes

Effects of UV radiation exposure on DNA and DNA repair enzymes

... for the cluster in Endo III was accepted on the basis of in vitro work that showed the cluster to be resistant to reduction and oxidation, in solution [20, ...Combination of kinetic, ... See full document

144

SOCIAL ECONOMY – A FORM OF INCLUSION AND OF ''REACTIVATING'' OF LABOR IN THE CONTEXT OF THE CURRENT CRISIS

SOCIAL ECONOMY – A FORM OF INCLUSION AND OF ''REACTIVATING'' OF LABOR IN THE CONTEXT OF THE CURRENT CRISIS

... Despite the exigencies of the European Union regarding the active inclusion , which means to ensure labor markets for those looking for a job and for the disadvantaged persons , in ... See full document

13

The Influence of Small Amounts of Aluminium on the Spheroidization of Cast Iron with Cerium Mischmetal

The Influence of Small Amounts of Aluminium on the Spheroidization of Cast Iron with Cerium Mischmetal

... determine the influence of aluminium in the amount from about ...on the structure of cast iron treated with cerium mischmetal and subjected to graphitizing modification with 75% ... See full document

6

Muhammad Umair2 , Sarwat Ali2

Muhammad Umair2 , Sarwat Ali2

... top of a ...allowed the DNA strand to break and unwind. Later, the power supply was adjusted at 24 volts and 300 ...mL). DNA damage was determined by measuring the ... See full document

10

Caracterização da resposta SOS em Leptospira interrogans sorovar Copenhageni

Caracterização da resposta SOS em Leptospira interrogans sorovar Copenhageni

... Existence of a second DNA damage response pathway, RecA-independent, was observed for ...leptospira. The newly identified SOS component, mutY, links SOS response to oxidative DNA ... See full document

116

Actividade moduladora de extracto de Ginkgo biloba no ciclo celular de Saccharomyces cerevisiae e capacidade de reparação de danos de DNA em células sob stresse replicativo

Actividade moduladora de extracto de Ginkgo biloba no ciclo celular de Saccharomyces cerevisiae e capacidade de reparação de danos de DNA em células sob stresse replicativo

... one of the best-selling medicinal products worldwide due to its antioxidant ...decrease of cerebral insufficiency, increase of cerebral blood flow and circulation, and beneficial effects in ... See full document

46

DNA damage focus analysis in blood samples of minipigs reveals acute partial body irradiation.

DNA damage focus analysis in blood samples of minipigs reveals acute partial body irradiation.

... application of ionizing radiation (IR) in clinical therapeutic procedures and radiation accidents are major sources of human IR ...into the category of partial body irradiation (PBI) ... See full document

10

A PHF8 homolog in C. elegans promotes DNA repair via homologous recombination.

A PHF8 homolog in C. elegans promotes DNA repair via homologous recombination.

... examined the roles of two PHF8 homo- logs, JMJD-1.1 and JMJD-1.2, in the model organism ...to DNA dam- age. A deletion mutation in either of the genes led to hypersensitivity to ... See full document

16

Synthesis Of Arts In Architecture Of Uzbekistan Of The Ancient Period

Synthesis Of Arts In Architecture Of Uzbekistan Of The Ancient Period

... with the busts of musicians, gift-bearers was subjected to the unified principle of division of the entire space into rhythmic segments" [47, ...consider the case when ... See full document

8

The effects of anti-leukemia chemotherapy on LKB1-AMPK pathway functioning in acute myeloid leukemia cell lines

The effects of anti-leukemia chemotherapy on LKB1-AMPK pathway functioning in acute myeloid leukemia cell lines

... concentrations of ATRA [57, 63, 64]. Thus, the transcription of genes involved in differentiation is disrupted blocking the normal promyelocytic maturation [57, 63, ...capable of ... See full document

129

Operating characteristics of turbine mixers based on the analysis of power demand of the mixer’s drive

Operating characteristics of turbine mixers based on the analysis of power demand of the mixer’s drive

... demand of a mixing system in a roller mixer is shown in Fig 1. During the mixing cycle the power demand increases with an increase in the surface area of grains covered with clay-water ... See full document

4

Prevalence of Germline Mutations in Genes Engaged in DNA Damage Repair by Homologous Recombination in Patients with Triple-Negative and Hereditary Non-Triple-Negative Breast Cancers.

Prevalence of Germline Mutations in Genes Engaged in DNA Damage Repair by Homologous Recombination in Patients with Triple-Negative and Hereditary Non-Triple-Negative Breast Cancers.

... devoid of the C-terminal domain that appears to be nec- essary for BRCA2/PALB2 complex formation [51] and homologous recombination repair ...[28]. The NBN-c.511A>G variant reduces ... See full document

14

Identification of the DNA repair defects in a case of Dubowitz syndrome.

Identification of the DNA repair defects in a case of Dubowitz syndrome.

... sequenced the cDNAs of several NHEJ genes including KU70 (XRCC6), KU80 (XRCC5), XRCC4, DCLRE1C (Artimes), XLF (Cernunnos) and LIG4 (DNA Ligase ...in the LIG4 gene were identified in both ... See full document

11

Einstein (São Paulo)  vol.12 número2

Einstein (São Paulo) vol.12 número2

... product of Dicer processing enters the RISC pathway, resulting in the elimination of one of the strands, leaving the mature single-stranded miRNA associated with ... See full document

3

The application of optical measurements for the determination of accuracy of gear wheels casts manufactured in the RT/RP process

The application of optical measurements for the determination of accuracy of gear wheels casts manufactured in the RT/RP process

... discusses the possibilities of using optical measurements for defining the geometric accuracy of gear wheels casts manufactured in the rapid prototyping ...process. The tested ... See full document

4

The modification process of AlSi21CuNi silumin and its effect on change of mechanical properties of the alloy

The modification process of AlSi21CuNi silumin and its effect on change of mechanical properties of the alloy

... mechanism of modification of these precipitations one should take into account that effect of modification of hypereutectic silumins depends on earlier transition to liquid phase of ... See full document

4

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