[PDF] Top 20 TIM-3 genetic variants and risk of Behçet disease in the Iranian population
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TIM-3 genetic variants and risk of Behçet disease in the Iranian population
... to the existence of different polymorphism loci in the TIM-3 gene that may influence risk of disease and were not tested in this ...study. ... See full document
5
Genetic Variation in the REL Gene Increases Risk of Behcet's Disease in a Chinese Han Population but That of PRKCQ Does Not.
... rs702873, and rs842647) and PRKCQ polymorphisms (rs4750316, rs11258747, and rs947474) were genotyped by polymerase chain reaction-restric- tion fragment length polymorphism ...Amplification of ... See full document
8
Identification of genetic risk factors for Behçet’s disease
... nature of clinical BD manifestations raised also the question of whether HLA-B*51/B*5 could have a modulatory effect on disease ...HLA-B*51/B*5-positive and negative BD patients ... See full document
215
Helicobacter pylori infection synergizes with three inflammation-related genetic variants in the GWASs to increase risk of gastric cancer in a Chinese population.
... limitations of our study need to be addressed. First, the sample size, especially the cardia GC cases, was not large and the statistical power of the study may have been ... See full document
8
Genetic Variants Underlying Risk of Intracranial Aneurysms: Insights from a GWAS in Portugal
... represent the gold-standard approach for uncovering novel genetic risk variants and have brought novel insights into the biological and genetic underpinnings ... See full document
12
Mitochondrial DNA Variants in a Portuguese Population of Patients with Alzheimer’s Disease
... primary risk factor for AD in the population under study (central region of Portugal), which is in agreement with the current literature, but does not rule out the ... See full document
6
Association of Multiple Genetic Variants with the Extension and Severity of Coronary Artery Disease
... effects of LPL, APOA5 and APOE variant combinations on triglyceride levels and hypertriglyceridemia: results of the ICARIA genetic sub- ...AI-CIII-AIV genetic ... See full document
8
Multi-analytic approach elucidates significant role of hormonal and hepatocanalicular transporter genetic variants in gallstone disease in North Indian population.
... phisms and risk of gallstones are biologically ...that the gallbladder is a female sex hormone responsive organ, and these hormones might be involved in the pathogenesis ... See full document
9
Genetic variants in the G gamma-globin promoter modulate fetal hemoglobin expression in the Colombian population
... for the development of sickle cell anemia. High HbF levels lower the intensity of symptoms of this ...vary in patients with sickle cell anemia and individuals without ... See full document
7
APOL1 risk variants and kidney disease: what we know so far
... differences in chronic kidney disease between Caucasians and African ...gene variants are strongly associated with focal segmental glomerulosclerosis, HIV- associated nephropathy, hypertensive ... See full document
15
Genetic variants at 1p11.2 and breast cancer risk: a two-stage study in Chinese women.
... studies in Caucasian populations on 1p11.2 and breast cancer susceptibility identified the marker SNP of ...to the transcription start site of NOTCH2, a gene associated with ... See full document
8
Type 2 diabetes-associated genetic variants of FTO, LEPR, PPARg, and TCF7L2 in gestational diabetes in a Brazilian population
... resulting in a change of lysine to arginine at codon 109 (Figure ...with the AA genotype are 2-fold more likely to develop T2DM than those with other genotypes ...(47). The LEPR rs1137101 ... See full document
11
APOL1 risk variants and kidney disease: what we know so far
... with the HRG lose glomeruli since the first decades of life, while the general healthy population begins to lose glomeruli from the age of ...incidence in carriers ... See full document
15
APOL1 risk variants and kidney disease: what we know so far
... differences in chronic kidney disease between Caucasians and African ...gene variants are strongly associated with focal segmental glomerulosclerosis, HIV- associated nephropathy, hypertensive ... See full document
15
APOL1 risk variants and kidney disease: what we know so far
... differences in chronic kidney disease between Caucasians and African ...gene variants are strongly associated with focal segmental glomerulosclerosis, HIV- associated nephropathy, hypertensive ... See full document
15
The relationship between genetic risk variants with brain structure and function in bipolar disorder : a systematic review of geneticneuroimaging studies
... that the effects of genetic variants on inter- mediate neuroimaging phenotypes could be independent ...tropic) of effects on the clinical phenotype per se (Gottesman and ... See full document
23
Pro-inflammatory genetic polymorphims and risk of developing Celiac disease : Título em
... heritable disease that clusters in families. The disease risk for a sibling of an affected individual is 20 to 60 times higher than a member of the general ... See full document
28
Impact of Genetic Variants of Apolipoprotein E on Lipid Profile in Patients with Parkinson's Disease
... pathogenesis of Parkinson’s disease (PD) seems to involve genetic susceptibility to ...a risk factor for PD. his study aimed to evaluate the association of APOE polymorphism with ... See full document
8
Alcohol consumption, genetic variants in alcohol deydrogenases, and risk of cardiovascular diseases: a prospective study and meta-analysis.
... studies, the overall RR of CVD was ...carrying the ADH1C*2/2 slow metabolizing genotype as compared to ADH1C*1/1 (Figure ...differences in risk estimates between ischemic heart ... See full document
11
GALC deletions increase the risk of primary open-angle glaucoma: the role of Mendelian variants in complex disease.
... Association of the GALC CNV was replicated in a second Caucasian POAG case/control ...consisted of 959 cases and 1104 examined normal controls genotyped with realtime PCR that were ... See full document
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