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[PDF] Top 20 Transcription factor Oct1 is a somatic and cancer stem cell determinant.

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Transcription factor Oct1 is a somatic and cancer stem cell determinant.

Transcription factor Oct1 is a somatic and cancer stem cell determinant.

... (PBS), and permeabilized using PBS with ...1B and Figure ...sectioned and used for Figure 1D. Deparaffinization, hydration and antigen retrieval of human formalin-fixed paraffin-embedded ... See full document

14

STAT3 as a Key Factor in Tumor Microenvironment and Cancer Stem Cell

STAT3 as a Key Factor in Tumor Microenvironment and Cancer Stem Cell

... angiogenesis and immune functions within tumor ...transducer and activator of transcription 3 (STAT3), which is a point of convergence for numerous oncogenic signalling pathways, is ... See full document

1

Membrane-to-nucleus signaling links insulin-like growth factor-1- and stem cell factor-activated pathways.

Membrane-to-nucleus signaling links insulin-like growth factor-1- and stem cell factor-activated pathways.

... KITLG is required for diverse developmental and physiological processes such as hematopoiesis, pigmentation, gametogenesis, spatial learning, cardiomyocyte differentiation and repair, vasculogenesis ... See full document

16

Galiellalactone inhibits stem cell-like ALDH-positive prostate cancer cells.

Galiellalactone inhibits stem cell-like ALDH-positive prostate cancer cells.

... transducer and activator of transcription 3 (STAT3) is an important transcription factor in many cancer types and it has been shown to be involved in drug resistance ... See full document

9

Sensitivity to TOP2 targeting chemotherapeutics is regulated by Oct1 and FILIP1L.

Sensitivity to TOP2 targeting chemotherapeutics is regulated by Oct1 and FILIP1L.

... doxorubicin and etoposide are frontline chemotherapeutics for a wide variety of solid and hematological malignancies, including breast and ovarian adenocarcinomas, lung cancers, soft tissue sarcomas, ... See full document

8

CITED2 and the modulation of the hypoxic response in cancer

CITED2 and the modulation of the hypoxic response in cancer

... VHL and proteasomal degradation. Consequently, HIF-1α translocates and accumulates in the nucleus, and associates with the HIFβ subunit to form HIF-1 and to bind to specific hypoxia- response ... See full document

19

Is ‘msonge’ a house? Visualizing a novel in the L2 classroom: The case of Swahili

Is ‘msonge’ a house? Visualizing a novel in the L2 classroom: The case of Swahili

... Dwelling is one of the basic human needs and therefore it is found in all societies, but in various ...roof, and one or more floors. A dwelling is among the basic needs of humans ... See full document

15

CSPG is a secreted factor that stimulates neural stem cell survival possibly by enhanced EGFR signaling.

CSPG is a secreted factor that stimulates neural stem cell survival possibly by enhanced EGFR signaling.

... nsphs and using the neural colony- forming cell assay ...Nestin and Ki67 (Fig. 4C). The NCFCA is based on the hypothesis that NSCs have greater proliferative potential and will give ... See full document

13

Dissertation submitted to Faculdade de Ciências Médicas Universidade Nova de Lisboa for the degree of Doctor in Oncology - Breast Cancer SandraMargaridaCaldasAmaral

Dissertation submitted to Faculdade de Ciências Médicas Universidade Nova de Lisboa for the degree of Doctor in Oncology - Breast Cancer SandraMargaridaCaldasAmaral

... A decisão da terapêutica hormonal no tratamento do cancro da mama baseia- se na determinação do receptor de estrogénio alfa por imunohistoquímica (IHC). Contudo, a presença deste receptor não prediz a resposta em todas ... See full document

136

The role of the transcription factor SIM2 in prostate cancer.

The role of the transcription factor SIM2 in prostate cancer.

... vitro transcription step according to the manufacturer’s ...fragmented and hybridized to arrays’ according to the manufacturer’s protocols as described previously ...factors, and 39-59 ratio of ... See full document

10

Prognostic Value of Basic Fibroblast Growth Factor (bFGF) in Lung Cancer: A Systematic Review with Meta-Analysis.

Prognostic Value of Basic Fibroblast Growth Factor (bFGF) in Lung Cancer: A Systematic Review with Meta-Analysis.

... HR and 95%CI, we contacted the corresponding author, but received no ...source and concentration, and threshold cut-off values may introduce more bias as ...IHC is a relatively complicated ... See full document

14

Impacto do diabetes induzido por estreptozotocina na resposta hipertrófica dos músculos...

Impacto do diabetes induzido por estreptozotocina na resposta hipertrófica dos músculos...

... (EDL) and soleus (slow-twitch) muscles of streptozotocin-induced diabetic rats were ...i.v.) and maintained under this condition for four ...total and phosphorylated Akt and S6 were evaluated ... See full document

21

Rev. Bras. Hematol. Hemoter.  vol.38 número4

Rev. Bras. Hematol. Hemoter. vol.38 número4

... size and the amount of RNA and classified as being low (LFR), medium (MFR) or high (HFR) fluorescence reticu- locyte ...HFR and MFR correspond to ...reticulocytes, and is studied as an ... See full document

4

TACC3 is essential for EGF-mediated EMT in cervical cancer.

TACC3 is essential for EGF-mediated EMT in cervical cancer.

... growth factor b (TGF-b) and insulin-like growth factor 1 (IGF-1) have been shown to induce EMT and are significantly associated with the invasiveness, metastasis and recurrence of ... See full document

12

Role of the Cyclosporin-sensitive Transcription Factor NFAT1 in the Allergic Response

Role of the Cyclosporin-sensitive Transcription Factor NFAT1 in the Allergic Response

... antigen, and the accumulation of eosinophils in the pleural cavity was ...cavity and a corresponding increase in the level of serum IgE (Xanthoudakis et ...ficient and do not show any gross ... See full document

9

Estrogenic Regulation of the SCF/c-KIT System in Prostate Cells: a Relationship with Prostate Cancer?

Estrogenic Regulation of the SCF/c-KIT System in Prostate Cells: a Relationship with Prostate Cancer?

... protein is constituted by three distinct regions ...domain, and an extracellular domain responsible for recognizing and binding to c-KIT (Langley et ...(sSCF) is generated by the specific ... See full document

110

Efeitos da intervenção nutricional pós-operatória com vitaminas do complexo B sobre os indicadores metabólicos da via sulfurada e a sobrevida de pacientes com câncer de esôfago

Efeitos da intervenção nutricional pós-operatória com vitaminas do complexo B sobre os indicadores metabólicos da via sulfurada e a sobrevida de pacientes com câncer de esôfago

... every cell, there is an ongoing battle between the production of oxidants components from the aerobic metabolism and the antioxidants of enzymatic and non- enzymatic ...esophageal ... See full document

56

Aberrant signaling pathways in medulloblastomas: a stem cell connection

Aberrant signaling pathways in medulloblastomas: a stem cell connection

... Medulloblastoma is a highly malignant primary tumor of the central nervous ...tumor and the leading cause of death related to cancer in early ...chemotherapy and radiotherapy which may lead to ... See full document

6

CELLULAR REPROGRAMMING STRATEGIES FOR DEGENERATIVE DISORDERS INVOLVING THE RETINAL PIGMENT EPITHELIUM

CELLULAR REPROGRAMMING STRATEGIES FOR DEGENERATIVE DISORDERS INVOLVING THE RETINAL PIGMENT EPITHELIUM

... sickle- cell anemia. A genetic defect in the β-globin gene is responsible for this disorder and mutated iPS cells were corrected for the single gene defect through homologous ...iPS cell-based ... See full document

276

Exploring cell reprogramming techniques for Angelman Syndrome disease modelling

Exploring cell reprogramming techniques for Angelman Syndrome disease modelling

... old and age and gender-matched patient-derived fibroblasts into induced neurons following a dox- inducible lentiviral strategy for expression of ASCL1 and NGN2 neural-specific transcription ... See full document

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