[PDF] Top 20 Treatment of patients with metastatic colorectal cancer and poor performance status: current evidence and challenges

... low performance status (3 or 4), no benefit from prior evidence-based interventions, not eligible for a clinical trial, and with no strong evidence supporting the clinical value ... See full document

... cluded patients with previously untreated metastatic colorectal cancer (mCRC) and Eastern Cooperative Oncology Group (ECOG) performance status from 0 to ...2. ... See full document

... nature of this study means that potential bias cannot be ...number of factors that could bias towards the ...recording of adverse events, missing data, or patients having early dose ... See full document

... Metastatic colorectal cancer (mCRC) is still one of the tumor types with the highest incidence and mortal- ...2012, colorectal cancer was the second most prevalence ... See full document

... Eighteen patients treated with oxaliplatin for colorectal cancer were prospectively assessed before and immediately following oxaliplatin ...Three of these patients were ... See full document

... consists of two sections: in the first, information on weight history, food intake, nutrition impact symp- toms, and functional capacity is collected, and in the second section, diagnosis, disease ... See full document

... physicians with the automated statistical parametric mapping program using SPECT datasets from 14 patients with neu- rological disorders ...images and found that statistical parametric mapping ... See full document

... lung cancer patients diagnosed (n = 285) between May 2005 and May 2009 were ...characteristics of never-smokers and ever-smokers (former and current) were compared using ... See full document

... 93% of patients with synchronous stage IV CRC who received chemotherapy did not require palliative surgery for the primary tumor ...symptomatic and is therefore considered on an individual ... See full document

... the metastatic sites, but not including procedures only used for di- agnosis; chemotherapy, including the use of anti-cancer drugs administered by any means; hormonal treatment, ...form ... See full document

... Blood and lymphatic vessel proliferation is essential for tumor growth and ...Most colorectal carcinomas develop from adenomas (adenoma-carcinoma sequence) in a process due to accumulation of ... See full document

... Consistent with previous reports [10], we found minimal overlap among these gene expression signatures at individual gene level (Figure ...level of False Discovery Rate (FDR) less than ...3.21e-12) ... See full document

... surface with the electric arc with the use of the FALTIG 315AC/DC ...The treatment parameters were used: amperage of the electric arc I = 100 A, speed of the electrode movement ... See full document

... context of the cohesion policy, solidarity must represent a support for development ...self‐help and its success depends a great deal on the capacity and the training of the people to whom the ... See full document

... study of panitumumab with fluorouracil, leucovorin, and irinotecan(FOLFIRI) compared with FOLFIRI alone as second- line treatment in patients with metastaticcolorectal ... See full document

... role of telomeres and telomerase in colorectal cancer (CRC) is well established as the major driving force in generating chromosomal ...implications of telomeres and telomerase ... See full document

... Introduction. Colorectal cancer (CRC) is the third com- monly diagnosed cancer that causes more than 600 000 deaths per year worldwide ...year with- out noticeable ...tumors of less ... See full document

... results of studies on the use of FeSi5%Mg magnesium alloy in modern cored wire injection method for production of nodular and vermicular graphite cast irons were ...injection of Mg ... See full document

... provide evidence on three mechanisms that can reconcile somewhat frequent price changes with large and persistent real e¤ects of monetary ...degrees of real rigidities, and ... See full document

... business and would be better off in this counter-factual scenario, as they are no longer constrained by the growth limitations imposed by ...bunching of informal firms near the transition ...absence ... See full document