[PDF] Top 20 Unravelling the role of ACOX3 and MCT2 in prostate cancer

... present in bacteria and archaea. This system, in similarity to the mammalian immune system, keeps a record of previous infections, in order to reduce the effects of ... See full document

... diagnosis of PCa is the physical examination by the digital rectal examination (DRE) combined with the PSA blood test screening (Kelly et ...by the prostate-specific gene ... See full document

... expressed in a global miRNA expression study in which the authors have used matched samples collected from the prostates harboring cancer as controls ...was the most ... See full document

... RESULTS AND DISCUSSION: Expression profiling identified 173 differently expressed miRNAs out of ...740. Of these 173, 47 were considered significantly downregulated and 5 upregulated, ... See full document

... possible, in part, by an award provided by the Division of Cancer Control and Population Sciences and the Division of Cancer Prevention of the ... See full document

... Prostate cancer (PCa) is the most common type of oncological disorder in men, for which an increasing incidence has been ...Development and progression of PCa have been ... See full document

... samples of 197 primary tumors and 45 HGPIN (from here simply designated PIN) lesions were prospectively collected from patients diagnosed with the disease and primarily treated with RP, form ... See full document

... Prostate cancer is the most common form of non-skin cancer and the second leading cause of cancer deaths in the United States ...[1]. ... See full document

... regulated in the most aggressive metastatic cell line PC-3 when compared to ...decrease in Claudin 7 expression correlated with high grade prostatic tumours ...reflection of the ... See full document

... is the most 5’ member of the HOXB ...601bp and 254bp, respectively, with a 5’ UTR region of 585bp and a 3’ UTR region of 2027bp [ENSG00000159184, (Flicek et ...occurs ... See full document

... [27] and has an important role in chromatin compartmentalization; moreover, we have shown that in human PCa, lamin B undergoes a significant increase correlated to the Gleason score ... See full document

... Prostate cancer (PCa) is a leading cause of cancer-related morbidity and mortality, ...worldwide. The widespread use of serum PSA for early detection led to a decrease ... See full document

... four of the 200 PCa presented two different ETS rearrangements in the index tumor, therefore representing intratumor genetic ...gene and an ETV4 rear- rangement, whereas three ... See full document

... that cancer cells preferentially rely on glycolysis for energy production, even in the presence of oxygen, leading to the production of high levels of lactate ...for ... See full document

... upregulated in PCa, producing two RNA isoforms that overlap completely at the ...5’-end. The shorter isoform is 3.7 kB in length and more abundant than the longer, 23 kB, isoform ... See full document

... MCT1 and MCT4 have been extensively described at the plasma membrane of solid tumours as major players in the acid-resistant phenotype of tumour cells [22, 23] and ... See full document

... is the most sensitive to DRP1 and BRAF inhibition. C643 and 8505C have analogous responses to both ...that the drug effects depend more on doses than on exposure ...since the lowest ... See full document

... expression in a total of 24 normal and tumor prostatectomy samples shown in table ...exists in two isoforms, SIM2 short (SIM2s) and SIM2 long (SIM2L), we confirmed the ... See full document

... series of paraffin- embedded biopsies from 60 PCa patients for relative 8q24 gain (Ribeiro et ...each of the sixty biopsy samples, a commercial dual-color probe flanking the MYC gene at 8q24 ... See full document

... localization and staging of prostate cancer over the last ...Weighted-Imaging and at least two functional techniques, which include Dynamic Contrast–Enhanced Magnetic Resonance ... See full document