[PDF] Top 20 Unravelling the roles of statistical proteomes in human cancer
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Unravelling the roles of statistical proteomes in human cancer
... from the Medical School, University of Cape Town in 1991 and then reproduced, maintained and housed at IPATIMUP Animal House, at the Medical Faculty of the University of ... See full document
316
The Roles of ROS and Caspases in TRAIL-Induced Apoptosis and Necroptosis in Human Pancreatic Cancer Cells.
... expression of DcRs ...geted in several clinical trials [5, 6]. Binding of TRAIL to DR on cancer cells provides caspase- 8-dependent death signaling and triggers the ‘extrinsic’ ... See full document
15
DUAL ROLES OF CANCER CELL-EXPRESSED IMMUNOGLOBULINS IN CANCER IMMUNOLOGY
... While the expression of immunoglobulins and T cell receptors on cancer cells has been well-established for decades, the potential roles and mechanisms of action of these ... See full document
10
Single-cell transcriptomics in unravelling the molecular complexity of immunity in human disease
... Although the development of scRNA-seq protocols was motivated by the need to study conditions where only a small amount of material was available, such as cells from the early embryonic ... See full document
96
Unravelling new ethnopharmacological roles of Plectranthus species: biological activity screening
... AChE in vitro enzymatic assay was performed in order to find new inhibitors, due to the importance of AChE in the human skin, apart from its extensively known relevance ... See full document
103
Reproducible Analysis of Post-Translational Modifications in Proteomes--Application to Human Mutations.
... test the hypothesis of whether disease-causing mutations, based on the ‘Clinical Signifi- cance’ category within dbSNP [17], are more likely to be near sites of PTMs, we found that we first ... See full document
14
Glycosylation in cancer: Selected roles in tumour progression, immune modulation and metastasis
... [96]. In addition, it has become apparent that the enzymes that regulate glycan modification of HSPGs are also powerful regulators of tumour behaviour ...[97]. The HSPGs act ... See full document
31
Characterization of metastasis formation and virotherapy in the human C33A cervical cancer model.
... spread of C33A-RFP cells in nude mice after s.c. implantation of tumor cells was characterized, we set out to analyze the possibility of an oncolytic virotherapy as a novel treatment ... See full document
11
Differential Predictive Roles of A- and B-Type Nuclear Lamins in Prostate Cancer Progression.
... and the sections were rehydrated with graded series of ...All the antibodies were tested on prostate TMA test blocks prior to use in the final TMA material in order to optimize ... See full document
16
Context-dependent roles for lymphotoxin-beta receptor signaling in cancer development
... arise in sites of chronic inflammation [142], which provide a microenvironment containing various mediators ...migration. In this context, Haybaeck and co-workers have found the involvement ... See full document
38
Revisiting the roles of VHRDUSP3 phosphatase in human diseases
... different cancer types, including approximately 50 cancer subtypes or clinical variables, in this web ...illustrate the potential of this toolkit (and because these topics are very ... See full document
7
MicroRNA-455 suppresses the oncogenic function of HDAC2 in human colorectal cancer
... development of CRC is strongly associated with imbalance between cell proliferation and apoptosis ...apoptosis in human CRC cells ...explored the effect of HDAC2 suppression on cell ... See full document
7
Unravelling the causes of inner ear disease
... patterns in which anatomical function pathology was observed in the hair cells and in the spiral ganglion nerve cells 29 ...conducted in European descendent (Non-Finnish and ... See full document
51
Evaluation of the role of LRP1B in the response of human ovarian cancer cells to liposomal doxorubicin
... µL of Lipofectamine 3000 transfection reagent in 25 µL of Opti-MEM I Reduced Serum Media ...µL of Opti-MEM: i) Opti-MEM only (to control for possible transfection toxicity of the ... See full document
76
Unravelling the Role of Methylprednisolone on Neuromuscular Transmission in Myasthenia Gravis
... diagnosis of MG begins with the correct evaluation of the patient, proper anamnesis, physical examination, including neurological examination, which should lead to suspect from ...consist ... See full document
40
Unravelling the role of glutamine synthetase in seed development in Arabidopsis thaliana
... 2002). The two fertilization products, embryo and endosperm, are surrounded by the seed coat, which ensures their protection throughout seed development and after the seeds being detached from ... See full document
114
Cytotoxicity of portoamides in human cancer cells and analysis of the molecular mechanisms of action
... work, the cyanobacterial strain Phormidium ...conditions in order to isolate portoamides A and B (designated portoamides in the following ...sections). The aim of the ... See full document
18
Expression of the human glucokinase gene: important roles of the 5' flanking and intron 1 sequences.
... downstream of the luciferase coding sequence lower reporter gene activity was observed for both the 1049 and 3815 base liver-specific glucokinase promoter constructs ...portion of the ... See full document
13
The diversity of gender roles in the Andes: implications for tourism
... factor in tourism (Kinnaird & Hall, 1996; Swain, 1995). However, the concepts of gender and equality are frequently not clearly defined and applied in dif- ferent ways (Ferguson, ...people ... See full document
11
Proteomic interrogation of androgen action in prostate cancer cells reveals roles of aminoacyl tRNA synthetases.
... differences in the physico-chemical properties of the identified peptides ...Thus, the strategy of using two different mass spectrometers, which differ both in their ... See full document
12
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