[PDF] Top 20 Vaccination against IL-33 Inhibits Airway Hyperresponsiveness and Inflammation in a House Dust Mite Model of Asthma.

... understanding of the initial regulation of inflammatory responses, includ- ing the function of barriers, has advanced ...regulators of events that can lead to the development of ... See full document

... the model of HDM-induced asthma used herein is closely related to the reality of asthma with a transcutaneous allergen sensitization, and a mixed Th1/Th17 inflammation ... See full document

... Allergic asthma is characterized as a chronic airway inflamma- tion disease, and it is well recognized that a variety of inflammatory cells play a key role in this process ...sites ... See full document

... Levels of asymmetric dimethylarginine (ADMA), an endogenous inhibitor of nitric oxide synthase, are increased in lung, sputum, exhaled breath condensate and plasma samples from asthma ... See full document

... absence of adjuvant, stimulation of TLR4 on airway structural cells has been shown to be necessary for priming of innate immune responses and for the development of airway ... See full document

... reduction in the number of sputum eosinophils after treatment ...evaluating IL-5 (in pg/mL) before and after treatment with prednisone or prednisolone (n = 114), there was an ... See full document

... Forty-two House Dust Mite --- sensitized children with allergic rhinitis were enrolled and received House Dust Mite allergen extract for sublingual immunotherapy or ... See full document

... consists of intermittent airway obstruction, bronchial hyperreactivity and chronic inflammation with airways' structural ...attenuate inflammation and prevent remodeling ... See full document

... role in initiating and propagating the allergic response, as GILT has other known functions apart from its involvement in antigen ...reducing and activating listeriolysin O [22], and it ... See full document

... function in both innate immunity and adaptive ...D inhibits proliferation of CD4+T cells ...production of cytokine IL-17 and IFN-g (6,7). As for asthma, ... See full document

... trial of the effects of prednisone or prednisolone (in comparison with those of another treatment of eosinophilic bronchitis in asthma or versus a control) or a pre- ... See full document

... area and examined by a dermatolo- gist at the Dermatology and Venereology Unit, Karolinska University Hospital Stockholm, Sweden, during September until May to avoid the summer ...nosis of AD or SE ... See full document

... humans, house dust mites (HDMs) are major sources of indoor allergens which induce asthma, rhinitis, dermatitis, and other allergic diseases ...chemical and structural properties ... See full document

... effect of microbial metabolites is gradually known or accepted, owing to the multiplicity and complexity of diet-microbiota- immune system, the current understandings are still insufficient to ... See full document

... band of approximately 14 ...weight of 14 kDa (O’Hehir et al. 1993). None of the sera of the group of dogs with CAD recognized Der f 1, a major allergen for humans with a molecular ... See full document

... involved in the development of Th2-type immune responses to inhaled allergens? T cells from B cell-deficient mice have been shown to produce levels of Th2 cytokines that are comparable to those from ... See full document

... markers of remodeling, i.e. increased bronchial smooth muscle size and peribronchial fibrosis, were observed in groups B (day 75) and C (Day 110) ...use of Penh to assess BHR in ... See full document

... role of NO in inflammatory cell recruitment, no effects in eosinophil recruit- ment are still a matter of ...inhibitors of NO reduced allergen-induced eosinophilia (Feder et ... See full document

... express and characterize adult Dermatophagoides farinae group 1 (Der f 1) allergens to further produce recombinant allergens for future clinical applications in order to eliminate side reactions from crude ... See full document

... potentiation of SCF expression by the asso- ciation of IL-1ß and glucocorticoids at 30 min is related to increased SCF gene transcription (Da Silva et ...which in turn depends on the ... See full document