O extrato etanólico e suas frações derivadas de sementes de Licania rigida mostraram um perfil fenólico promissor com alta concentração de compostos com atividade antioxidante. No que se refere à presença de compostos que atuam através da varredura de radicais livres, flavonoides como a quercetina, quercitrina e catequina foram preponderantes. Já os ácidos fenólicos se mostraram mais importantes quando condições de estresse foram usadas (presença de ferro). Neste trabalho, também foi possível observar uma relação clara entre a presença de taninos e atividade antioxidante nas amostras FALr, FMLr e EELr.
De forma geral, o EELr apresentou baixa ou nenhuma toxicidade de acordo com os ensaios utilizados. No entanto, abordagens mais sensíveis como a toxicogenômica e ensaios de toxicidade de longa duração em animais devem ser feitos a fim de garantir a segurança de uso dessa promissora fonte de compostos antioxidantes.
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