• Nenhum resultado encontrado

Após a realização de todas as analises de isolamento, caracterização e diferenciação celular, podemos concluir que estas células progenitoras de membrana amniótica de coelho podem ser classificadas como células tronco mesenquimais multipotentes, uma vez que estas apresentam capacidade de expressar marcadores de células tronco mesenquimais, de pluripotência e não expressaram marcadores de células hematopoiéticas, além de se diferenciaram em linhagens celulares mesenquimais distintas, como definido por Dominici et al. (2006). Todavia a análise do potencial tumorigênico foi o ponto chave deste trabalho, uma vez que estas células devidamente caracterizadas e diferenciadas não apresentaram potencial tumoral, sendo esta avaliação fundamental para terapias futuras.

Devido a todas as características mencionadas sobre a caracterização destas células, elas também possuem alta capacidade de expansão e proliferação in vitro,

itens fundamentais para a criação de um banco de células. No entanto, a principal característica dessas células derivadas da membrana amniótica, é o fato desta membrana se encontrar na interface materno-fetal, possuindo assim uma baixa resposta imunológica, característica relacionada a expressão de MHC de classe I e estudos mais recentes demostraram sua capacidade de imunomodulação (FERNANDES et al., 2012; PAROLINI et al., 2008). Com isso podemos sugerir que estas células apresentam características desejáveis que podem assim, garantir a sua utilização com sucesso na medicina regenerativa para reconstituição, tratamento ou reparo de órgãos ou tecidos lesados.

REFERENCIA

ABUMAREE, M. H.; AL JUMAH, M. A.; KALIONIS, B.; JAWDAT, D.; AL KHALDI, A.; ALTALABANI, A. A.; KNAWY, B. A. Phenotypic and functional characterization of mesenchymal stem cells from chorionic villi of human term placenta. Stem Cell

Reviews and Reports, Totowa, v. 9, n. 1, p. 16-31, Feb. 2013.

AJAYI, F. O.; BALOGUN, O. O.; OVURU, S. S.; MGBERE, O. O. Reproductive performance of rabbits fed maize – milling waste based diets.African Journal of Biotechnology, Lagos, v. 4, n. 5, p. 439-443, 2005.

AKLE, C. A.; ADINOLFI, M.; WELSH, K. I. Immunogenicity of human amniotic

epithelial cells after transplantation into volunteers. Lancet, London, v. 2, n. 8254, p. 1003–1005, Nov. 1981.

ALVES, P. Estudo da reprodução e do estado de condição física de duas

populações portuguesas de Coelho-bravo. 1994. Dissertação - Faculdade de

Ciências Universidade do Porto, 1994.

ALVES, P. M. M.; CARRONDO, M. J. T.; CRUZ, P. E. Introdução à tecnologia de cultivo de células animais. In: MORAES, A. M.; AUGUSTO, E. F. P.; CASTILHO, L. R. Tecnologia do cultivo de células animais de biofármacos a terapia celular. Roca: São Paulo, 2007. Cap.1, p. 2-14.

ARORA, R.; PAPAIOANNOU, V. E. The murine allantois: a model system for the study of blood vessel formation. Blood, New York, v. 120, n. 13, p. 2562-2572, Sept. 2012.

ASAHARA, T.; KAWAMOTO, A. Endothelial progenitor cells for postnatal.

Vasculogenesis. American journal of physiology. Cell Physiology, Bethesda, v. 287, n. 3, p. C572–C579, Sept. 2004

BARON, M.H. Embryonic origins of mammalian hematopoiesis. Experimental

Hematology, Copenhagen, v. 31, n. 12, p.1160-1169. Dec. 2003.

BAILO, M.; SONCINI, M.; VERTUA, E.; SIGNORONI, P.B; SANZONE, S.;

LOMBARDI, G.; ARIENTI, D.; CALAMANI, F.; ZATTI, D.; PAUL, P.; ALBERTINI, A.; ZORZI, F.; CAVAGNINI, A.; CANDOTTI, F.; WENGLER, G.S.; PAROLINI, O.

Engraftment potential of human amnion and chorion cells derived from term placenta.

Transplantation, Baltimore, v. 78, n.10, p.439–448, Nov. 2004.

BANAS, R. A.; TRUMPOWER, C.; BENTLEJEWSKI, C.; MARSHALL, V.; SING, G.; ZEEVI, A. Immunogenicity and immunomodulatory effects of amnion-derived

multipotent progenitor cells. Human Immunology, New York, v.69, n. 6, p. 321-328, June. 2008.

BELTRAMI, A. P.; BARLUCCHI, L.; TORELLA, D.; BAKER, M.; LIMANA, F.; CHIMENTI, S.; KASAHARA, H.; ROTA, M.; MUSSO, E.; URBANEK, K; LERI, A.; KAJSTURA, J.; NADAL-GINARD, B.; ANVERSA, P. Adult cardiac stem cells are

multipotent and support myocardial regeneration. Cell, Cambridge, v. 114, n. 6, p. 763-776, Sept. 2003.

BENIRSCHKE, K.; KAUFMAN, P. Pathology of the human placenta Springer- Verlag: New York:, 2000, p. 273-281.

BOLLEROT, K.; POUGET, C.; JAFFREDO, T. The embryonic origins of

hematopoietic stem cells: a tale of hemangioblast and hemogenic endothelium.

APMIS : Acta Pthologica, Microbiologica, et Immunologica Scandinavica,

Copenhagen, v. 113, n. 11-12, p. 790-803, Nov-Dec. 2005

BORGHESI, J. Phenotype and multipotentiality of progenitor cells from the

amniotic membrane Rabbit (Oryctolagus cuniculus). [Fenótipo e

multipotencialidade de células progenitoras de membrana amniótica de Coelho

(Oryctolagus cuniculus)]. 2015. 77 f. Dissertação (Mestrado em Ciências)- Faculdade

de Medicina Veterinária e Zootecnia, Universidade de São Paulo, São Paulo, 2014. BRIGHTON, C. T.; HOZACK, W. J.; BRAGER, M. D.; WINDSOR, R. E.; POLLACK, S. R.; VRESLOVIC, E. J.; KOTWICK, J. E. Fracture healing in the rabbit fíbula when subjected to various capacitively electrical fields. Journal of Orthopaedic Research, New York, v. 3, n. 3, p. 331-340, 1985.

CALVIN, S. E.; OYEN, M. L. Microstructure and mechanics of the

chorioamnion membrane with an emphasis on fracture properties. Annals of the

New York Academy of Sciences, New York, v. 1101, p. 166-185, Apr. 2007.

CAPLAN, A. Adult mesenchymal stem cells for tissue engineering

versus regenerative medicine. Journal of Cellular Physiology, Philadelphia, v. 213, n. 2, p. 341-347, Nov. 2007.

CHAMBERS, I.; COLBY, D.; ROBERTSON, M.; NICHOLS, J.; LEE, S.; TWEEDIE, S.; SMITH, A. Functional expression cloning of Nanog; a pluripotency sustaining factor in embryonic stem cells. Cell, Cambridge, v. 113, n. 4, p. 643-655, May. 2003. CHANG, Y. J.; HWANG, S. M.; TSENG, C. P.; CHENG, F. C.; HUANG, S. H.; HSU, L. F.; HSU, L. W.; TSAI, M. S. Isolation of mesenchymal stem cells with neurogenic potential from the mesoderm of the amniotic membrane. Cells, Tissues, Organs,

Basel, v. 192, n. 2, p .93–105, Mar. 2010.

CIUCĂ, D. R.; SORIŢĂU, O.; ŞUŞMAN, S.; POP, V. I.; MIHU, C. M. Isolation and characterization of chorionic mesenchyal stem cells from the placenta. Romanian

Journal of Morphology and Embryology, Bucuresti, v. 52, n. 3, p. 803-808, 2011.

COLI, A.; NOCCHI, F.; LAMANNA, R.; IORIO, M. C.; LAPI, S.; URCIUOLI, P.; SCATENA, F.; GIANNESSI, E.; STORNELLI, M. R.; PASSERI, S. Isolation and characterization of equine amnion mesenchymal stem cells. Cell Biology International Reports, v. 18, n. 1, p. e00011, Sept. 2011.

CSAKI, C.; MATIS, U.; MOBASHERI, A.; YE, H.; SHAKIBAEI, M. Chondrogenesis, osteogenesis and adipogenesis of canine mesenchymal stem cells: a biochemical,

morphological and ultrastructural study.Histochemistry and Cell Biology, Berlin, v.

128, n. 6, p. 507-520, Dec. 2007.

CREMONESI, F.; CORRADETTI, B.; LANGE-CONSIGLIO, A. Fetal adnexa derived stem cells from domestic animals: progress and perspectives. Theriogenology, Los Altos, v. 75, n. 8, p. 1400-1415, May. 2011.

DIELBOLD, J. M.; MOLINA, T.; CAMILLERI-BROET, S.; LE TOURNEAU, U.; AUDOUIN, J. Bone marrow manifestations of infections and systemic diseases observed in bone marrow trephine biopsy. Histopathology, Oxford, v. 37, n. 3, p. 199-211, Sept. 2000.

DÍAZ-PRADO, S.; MUIÑOS-LÓPEZ, E.; HERMIDA-GÓMEZ, T.; RENDAL- VÁZQUEZ, M.E.; FUENTES-BOQUETE, I.; DE TORO, F. J.; BLANCO, F. J.

Stem cells from human amniotic membrane. Tissue Engineering: part C, New York, v. 17, n. 1, p. 49-59, Jan. 2011.

DOMINICI, M.; LE BLANC, K.; MUELLER, I.; SLAPER-CORTENBACH, E.; MARINI, F.; KRAUSE, D.; DEANS, R.; KEATING, A.; PROCKOP, D. J.; HORWITZ, E. Minimal criteria for defining multipotent mesenchymal stromal cells. The International Society for Cellular Therapy position statement. Cytotherapy, v. 8, n. 4, p. 315-317, 2006. FAVARON, P. O.; MESS, A.; WILL, S. E.; MAIORKA, P. C.; OLIVEIRA, M.F.; MIGLINO, M. A. Yolk sac mesenchymal progenitor cells from new world

Mice (Necromys lasiurus) with multipotent differential potential. PLoS ONE, San Francisco, v.9, n.6, p.e95575, June. 2014.

FERNANDES, R. A.; COSTOLA-SOUZA, C.; SARMENTO, C. A. P.; GONÇALVES, L.; FAVARON, P. O.; MIGLINO, M. A. Placental tissues as sources of stem cells— Review. Open Journal of Animal Sciences, v. 2, n. 3, p.166-173, June. 2012. FISCHER, B.; CHAVATTE-PALMER, P.; VIEBAHN, C.; SANTOS, A. N.;

DURANTHON, V. Rabbit as a reproductive model for human health. Reproduction, Cambridge, v. 144, n. 1, p. 1–10, July. 2012.

FRANCIOLLI, A. L. R. Medicina veterinária regenerativa: multipotencialidade das células da membrana amniótica e do saco vitelino no modelo equino (Equus

caballus, Linnaeus 1758). 2012. 191 f. Tese (Doutorado em Ciências) – Faculdade

de Medicina Veterinária e Zootecnia, Universidade de São Paulo, São Paulo, 2012. HILTUNEN, A.; VUORIO, E.; ARO, H. T. A standardized experimental fracture in mouse tibia. Journal of Orthopaedic Research, New York, v. 11, n. 2, p. 305-312,

Mar.1993.

HONDA, A.; HIROSE, M.; HATORI, M.; MATOBA, S.; MIYOSHI, H.; INOUE, K.; OGURA, A. Generation of induced pluripotent stem cells in rabbits: potential

experimental models for human regenerative medicine. The Journal of Biological

HORI, J.; WANG, M.; KAMIYA, K.; TAKAHASHI, H.; SAKURAGAWA, N.

Immunological characteristics of amniotic epithelium. Cornea,New York, v. 25, n. 10, p. S53-58, Dec. 2006.

HU, M. J.; RUAN, G.P.; YAO, X.; RUAN, G. H.; WANG, J. X.; PANG, R. Q.; CAI, X. M.; ZHU, X. Q.; HE, J.; PAN, X. H. Induced autologous stem cell transplantation for treatment of rabbit type 1 diabetes. Cell Biology International, London, v. 37, n. 6, p .624–632, June. 2013.

ILANCHERAN, S.; MICHALSKA, A.; PEH, G.; WALLACE, E. M.; PERA, M.; MANUELPILLAI, U. Stem cells derived from human fetal membranes

display multi-lineage differentiation potential. Biology of Reproduction, New York, v. 77, n. 3, p. 577-588, Sept. 2007.

INSAUSTI, C. L.; ALCARAZ, A.; GARCIA-VIZCAINO, E. M.; MROWIEC, A.; LÓPEZ- MARTÍNEZ, M. C.; BLANQUER, M.; PIÑERO, A.; MAJADO, M. J.; MORALEDA, J. M.; CASTELLANOS, G.; NICOLÁS, F. J. Amniotic membrane induces

epithelialization in massive posttraumatic wounds. Wound Repair and

Regeneration, St.Louis, v. 18, n. 4, p. 368–377,July-Aug. 2010.

IN 'T ANKER, P.S.; SCHERJON, S.A.; KLEIJBURG-VAN DER KEUR, C.; DE GROOT-SWINGS, G.M.; CLAAS, F.H.; FIBBE, W.E.; KANHAI, H.H. Isolation of mesenchymal stem cells of fetal or maternal origin from human placenta. Stem

Cells, Dayton, v.22, n.7, p.1338–1345, Dec. 2004.

ISMAIL, A.; RAMSIS, R.; SHERIF, A.; THABET, A.; EL-GHOR, H.; SELIM, A. Use of human amniotic stem cells for common bile duct reconstruction: Vascularized support of a free amnion graft. Medical Science Monitor : International Medical Journal of

Experimental and Clinical Research, Warsaw, v. 15, n. 9, p. BR243-247, Sept.

2009.

KAKISHITA, K.; NAKAO, N.; SAKURAGAWA, N.; ITAKURA, T. Implantation of human amniotic epithelial cells prevents the degeneration of nigral

dopamine neurons in rats with 6-hydroxydopamine lesions. Brain Research, Amsterdam, v. 980, n. 1, p .48-56, Aug. 2003.

KANYSHKOVA, T. G.; BUNEVA, V. N.; NEVINSKY, G. A. Lactoferrin and its biological functions. Biochemistry, New York, v. 66, n. 1, p. 1-7, Jan. 2001. KOLF, C. M.; CHO, E.; TUAN, R. S. Mesenchymal stromal cells. Biology of adult mesenchymal cells: regulation of niche, self-renewal and differentiation. Arthritis

Research Therapy, v. 9, p. 204, 2007.

KONG, X .Y.; CAI, Z.; PAN, L.; ZHANG, L.; SHU, J.; DONG, Y. L.; YANG, N.; LI, Q.; HUANG, X. J.; ZUO, P. P. Transplantation of human amniotic cells exerts

neuroprotection in MPTP-induced Parkinson disease mice. Brain Research, Amsterdam, v. 1205, p. 108-115, Apr. 2008.

KUBO, M.; SONODA, Y.; MURAMATSU, R.; USUI, M. Immunogenicity of human amniotic membrane in esperimental xenotransplantation. Investigative

Ophthalmology & Visual Science, St. Louis, v. 42, n. 7, p .1539-1546, June. 2001.

LANGE-CONSIGLIO, A.; CORRADETTI, B.; BIZZARO, D.; MAGATTI, M.; RESSEL, L.; TASSAN, S.; PAROLINI, O.; CREMONESI, F. “Characterization and potential applications of progenitor-like cells isolated from horse amniotic membrane,” Journal

of Tissue Engineering and Regenerative Medicine, Chichester, v. 6, n. 8, p. 622–

635, Aug. 2012.

LI, H.; NIEDERKORN, J. Y.; NEELAM, S.; MAYHEW, E.; WORD, R. A.; MCCULLEY, J. P.; ALIZADEH, H. Immunosuppressive factors secreted by human amniotic

epithelial cells. Investigative Ophthalmology & Visual Science, St. Louis, v. 46, n. 3, p. 900-907, Mar. 2005

LI, W.; HE, H.; KAWAKITA, T.; ESPANA, E. M.; TSENG, S.C. Amniotic membrane induces apoptosis of interferon-gamma activated macrophages invitro.

Experimental Eye Research, London, v. 82, n. 2, p. 282-292, Feb. 2006.

LIU, H. G.; LING-LING, E.; WANG, D. S.; WU, F. S. X.; SHI, Z. P.; YAN, L.V.; WANG, J. Z. Reconstruction of Alveolar Bone Defects Using Bone Morphogenetic Protein 2 Mediated Rabbit Dental Pulp Stem Cells Seeded on Nano-Hydroxyapatite/ Collagen/Poly(L-lactide. Tissue Engineering: Part A, New Rochelle, v. 17, n. 19-20, p. 2417-2433, Oct. 2011.

MAGATTI, M.; DE MUNARI, S.; VERTUA, E.; GIBELLI, L.; WENGLER, G. S.; PAROLINI, O. Human amnion mesenchyme harbors cells with allogeneic T-cell suppression and stimulation capabilities. Stem Cells, Dayton, v. 26, n. 1, p. 182–92, Jan. 2008.

MARCUS, A. J.; COYNE, T. M.; RAUCH, J.; WOODBURY, D.; BLACK, I. B. Isolation, characterization, and differentiation of stem cells derived from the rat amniotic membrane. Differentiation, London, v.76, n.2, p.130–144, July. 2008. MARCUS, A. J.; WOODBURY, D. Fetal stem cells from extra-embryonic tissues: do not discard. Journal of Cellular and Molecular Medicine, Bucharest, v. 12, n. 3, p.

730-742, June. 2008.

MARDONES, R.; MARTÍNEZ, R.; PAREDES, M. J.; ZALAQUETT, E. Chondrogenic differentiation of bone marrow mesenchymal stem cells. First successful Latin-

American report. International Journal of Morphology, v. 28, n. 3, p. 749-754,

Sept. 2010.

MATTIOLI, M.; GLORIA, A.; TURRIANI, M.; MAURO, A.; CURINI, V.; RUSSO, V.; TETÈ, S.; MARCHISIO, M.; PIERDOMENICO, L.; BERARDINELLI, P.; COLOSIMO, A.; MUTTINI, A.; VALBONETTI, L.; BARBONI, B. Stemness characteristics and osteogenic potential of sheep amniotic epithelial cells.Cell Biology International,

MAURO, A.; TURRIANI, M.; IOANNONI, A.; RUSSO, V.; MARTELLI, A.; DI

GIACINTO, O.; NARDINOCCHI, D.; BERARDINELLI, P. Isolation, characterization, and in vitro differentiation of ovine amniotic stem cells. Veterinary Research

Communications, Amsterdam, v. 34, n. 1, p. S25–S28, June. 2010.

MIHU, C. M.; CIUCA, D. R.; SORITAU, O.; SUSMAN, S.; MIHU, D. Isolation and characterization of mesenchymal stem cells from the amniotic membrane. Romanian

Journal of Morphology and Embryology, Bucuresti, v. 50, n. 1, p. 73–77, 2009.

MIKI, T.; LEHMANN, T.; CAI, H.; STOLZ, D.B.; STROM, S.C. Stem cell

characteristics of amniotic epithelial cells. Stem Cells, Dayton, v.23, n.10, p.1549– 1559, Nov-Dec. 2005.

MIKI, T.; MITAMURA, K.; ROSS, M.A.; STOLZ, D. B.; STROM, S. C. Identification of stem cell marker-positive cells by immunofluorescence in term

human amnion. Journal of Reproductive Immunology, Amsterdam, v. 75, n. 2, p

.91-96, Oct. 2007.

MIKI, T.; STROM, S. C. Amnion-derived pluripotent/multipotent stem cells.

Stem Cell Reviews and Reports, Totowa, v. 2, n. 2, p. 133–142, 2006.

MIMEAULT, M.; BATRA, S. K. Concise review: Recent advances on the significance of stem cells in tissue regeneration and cancer therapies. Stem Cells, Dayton, v. 24, n. 11, p. 2319–2345, Nov. 2006.

MINGUELL, J. J.; PEREIRA, A.; BARTHOLOMEW , P.; LASALA, G. P. The

intrathecal Infusion of mesenchymal stem cells into healthy rabbits is safe and devoid of neurological or clinical complications. Stem Cell Research & Therapy, v. 2, n. 1, p. 2-11, July. 2011.

MITHOEFER, K.; WILLIAMS, R. J.; WARREN, R. F.; POTTER, H. G.; SPOCK, C. R.; JONES, E. C.; WICKIEWICZ, T. L.; MARX, R. G. The microfracture technique for the treatment of articular cartilage lesions in the knee. A prospective cohort study. The

Journal of Bone and Joint Surgery, Boston, v. 87, n. 9, p. 1911-1920, Sept. 2005.

MOORE, K. L.; PERSUAD, T. V. N. Embriologia clínica. 7. ed. Rio de Janeiro: Elsevier, 2004. 609 p.

MOSSMAN, H. W. Vertebrate fetal membranes. Rutgers University Press: New Brunswick, 1987. 383 p.

MRUGALA, D.; DOSSAT, N.; RINGE, J.; DELORME, B.; COFFY, A.;

BONY, C.; CHARBORD, P.; HA¨ UPL, T.; DAURES, J. P.; NOE¨L, D.; JORGENSEN, C. Gene expression profile of multipotente mesenchymal stromal cells: identification of pathways common to TGFb3/BMP2-induced chondrogenesis. Cloning Stem

Cells, Larchmont, v. 11, n. 1, p. 61-76, Mar. 2009.

MUKAIDA, T.; YOSHIDA, K.; KIKYOKAWA, T.; SOMA, H. Surface structure of the placental membranes. Journal Clinical Electron Microscopy, v. 10, p. 447–448, 1977.

NEUPANE, M.; CHANG, C. C.; KIUPEL, M.; YUZBASIYAN-GURKAN, V. Isolation and characterization of canine adipose–derived mesenchymal Stem Cells. Tissue

Engineering Part A, New York, v. 14, n. 6, p. 1007-1015, June. 2008.

NUNAMAKER, V. M. D. Experimental model of fracture repair. Clinical

Orthopaedics and Related Research, New York, v. 355S, p. 57- 65, Oct. 1998.

OKAZAKI, T.; CASEY, M. L.; OKITA, J. R.; MACDONALD, P. C.; JOHNSTON, J. M. Initiation of human parturition. XII. Biosynthesis and metabolism of prostaglandins in human fetal membranes and uterine decidua. American Journal of Obstetrics and

Gynecology, St. Louis, v. 139, n. 4, p .373-381, Feb. 1981.

PARK, S. B.; SEO, M. S.; KIM, H. S.; KANG, K. S. Isolation and characterization of canine amniotic membrane-derived multipotent stem cells. PLoS ONE, San

Francisco, v. 7, n. 9, p. e44693, Sept. 2012.

PAROLINI, O.; ALVIANO, F.; BAGNARA, G. P.; BILIC, G.; BÜHRING, H.J.;

EVANGELISTA, M.; HENNERBICHLER, S.; LIU, B.; MAGATTI, M.; MAO, N.; MIKI, T.; MARONGIU, F.; NAKAJIMA, H.; NIKAIDO, T.; PORTMANN-LANZ, C.B.;

SANKAR, V.; SONCINI, M.; STADLER, G.; SURBEK, D.; TAKAHASHI, T.A.; REDL, H.; SAKURAGAWA, N.; WOLBANK, S.; ZEISBERGER, S.; ZISCH, A.; STROM, S.C. Concise review: isolation and characterization of cells from human term placenta: outcome of the first international workshop on placenta derived stem cells. Stem

Cells, Dayton, v. 26, n. 2, p. 300-311, Feb. 2008.

PAROLINI, O.; CARUSO, M. Review: Preclinical studies on placenta-derived cells and amniotic membrane: an update. Placenta, London, v. 32, n. 2, p. S186–95, Mar. 2011.

PAROLINI, O.; SONCINI, M. Human placenta: a source of progenitor/stem

cells? Journal of Reproductive Medicine and Endocrinology, v. 3, n. 3, p. 117– 126, Nov. 2006.

PAROLINI, O.; SONCINI, M.; EVANGELISTA, M.; SCHMIDT, D. Amniotic membrane and amniotic fluid-derived cells: potential tools for regenerative medicine?

Regenerative Medicine, London, v. 4, n. 2, p. 275–291, Mar. 2009.

PAROLINI, O.; SOUZA-MOREIRA, L.; O'VALLE, F.; MAGATTI, M.; HERNANDEZ- CORTES, P.; GONZALEZ-REY, E.; DELGADO, M. Therapeutic effect of human amniotic membrane-derived cells on experimental arthritis and other inflammatory disorders. Arthritis Rheumatol, Malden, v. 66, n.2, p. 327-339, Feb. 2014.

PERA, M.F.; REUBINOFF B, TROUNSON A. Human embryonic stem cells.Journal of Cell Science. London, v.13, p.5-10, Jan. 2000.

PORTMANN-LANZ, C. B.; SCHOEBERLEIN, A.; HUBER, A.; SAGER, R.; MALEK, A.; HOLZGREVE, W.; SURBEK, D. V. Placental mesenchymal stem cells as

potential autologous graft for pre- and perinatal neuroregeneration American

Journal of Obstetrics and Gynecology, St. Louis, v. 194, n. 3, p. 664–673, Mar.

ROSSI, D.; PIANTA, S.; MAGATTI, M.; SEDLMAYR, P.; PAROLINI, O. Characterization of the conditioned medium from amniotic membrane cells:

Prostaglandins as key effectors of Its immunomodulatory activity. PLoS ONE, San Francisco, v. 7, n. 10, p .e46956, Oct. 2012.

RUTIGLIANO, L.; CORRADETTI, B.; VALENTINI, L.; BIZARRO, D.; MEUCCI, A.; CREMPNESI, F.; LANGE-CONSIGLIO, A. Molecular characterization and in vitro differentiation of feline progenitor-like amniotic epithelial cells. Stem Cell Research

and Therapy, London, v. 4, n. 5, p. 133, Oct. 2013.

SAKURAGAWA, N.; ELWAN, M. A.; UCHIDA, S.; FUJII, T.; KAWASHIMA, K. Non-neuronal neurotransmitters and neurotrophic factors in amniotic epithelial cells: expression and function in humans and monkey. Japanese Journal of

Pharmacology, Kyoto, v. 85, n. 1, p. 20–23, Jan. 2001.

SAKURAGAWA, N.; ENOSAWA ,S.; ISHII, T.; THANGAVEL, R.; TASHIRO, T.; OKUYAMA, T.; SUZUKI, S. Human amniotic epithelial cells are promising transgene carriers for allogeneic cell transplantation into liver. Journal of Human Genetics, Tokyo, v. 45, n. 3, p. 171–176, Jan. 2000.

SANKAR, V.; MUTHUSAMY, R. “Role of human amnioticepithelial cell

transplantation in spinal cord injury repair research”. Neuroscience, Oxford, v. 118, n. 1, p. 11–17, Apr. 2003.

SEJPAL, K.; BAKHTIARI, P.; DENG, S. X. Presentation, diagnosis and management of limbal stem cell deficiency. Middle East African Journal of

Ophthalmology, Mumbai, v. 20, n. 1, p .5–10, Jan-Mar. 2013.

SEO, M. S.; PARK, S. B.; KIM, H. S.; KANG, J. G.; CHAE, J. S.; KANG, K. S. Isolation and characterization of equine amniotic membrane-derived mesenchymal stem cells. Journal of Veterinary Science, Suwon, v .14, n. 2, p. 151-159, Feb. 2013.

SONCINI, M.; VERTUA, E.; GIBELLI, L.; ZORZI, F.; DENEGRI, M.; ALBERTINI, A.; WENGLER, G. S.; PAROLINI, O. Isolation and characterization of mesenchymal cells from human foetal membranes. Journal of Tissue Engineering and

Regenerative Medicine, Chichester, v. 1, n. 4, p. 296–305, July-Aug. 2007.

SOUTHERN, H. N. The ecology and population dynamic of the wild rabbit

(Oryctolagus cuniculus). Annals of Applied Biology, v. 27, n. 4, p. 509-526, Nov.

1940.

TABATABAEI, M.; MOSAFFA, N.; NIKOO, S.;, BOZORGMEHR, M.; GHODS, R.; KAZEMNEJAD, S.; REZANIA, S.; KESHAVARZI, B.; AREFI, S.; RAMEZANI- TEHRANI, F.; MIRZADEGAN, E.; ZARNANI, A. H. Isolation and partial

characterization of human amniotic epithelial cells: the effect of trypsin. Avicenna

TODA, A.; OKABE, M.; YOSHIDA, T.; NIKAIDO, T. The potential of amniotic membrane/amnion-derived cells for regeneration of various tissues. Journal of

Pharmacological Sciences, Kyoto,v. 105, n. 3, p. 215-228, Nov. 2007.

TIEDEMANN, K. The Amniotic, Allantoic and Yolk Sac Epithelia of the Cat: SEM ant TEM Studies. Anatomy and Embryology, v. 158, p. 75-94, 1979.

TROUNSON, A. The production and directed differentiation of human

Embryonic stem cells. Endocrine Reviews, Baltimore, v. 27, n. 2, p. 208–219, Jan. 2006.

UCCELLI, A.; MORETTA, L.; PISTOIA, V. Mesenchymal stem cells in health and disease. Nature Reviews Immunology, London, v. 8, n. 9, p .726–736, Sept. 2008. URANIO, M. F.; VALENTINI, L.; LANGE-CONSIGLIO, A.; CAIRA, M.; GUARICCI, A. C.; L'ABBATE, A.; CATACCHIO, C. R.; VENTURA, M.; CREMONESI, F.;

DELL'AQUILA, M. E. Isolation, proliferation, cytogenetic, and molecular

characterization and in vitro differentiation potency of canine stem cells from foetal adnexa: a comparative study of amniotic fluid, amnion, and umbilical cord matrix.

Molecular Reproduction and Development, New York, v. 78, n. 5, p. 361–373,

May. 2011.

VIDANE, A. S.; SOUZA, A. F.; SAMPAIO, R. V.; BRESSAN, F. F.; PIERI, N. C.; MARTINS, D. S.; MEIRELLES, F.V.; MIGLINO, M. A.; AMBRÓSIO, C. E. Cat

amniotic membrane multipotent cells are nontumorigenic and are safe for use in cell transplantation. Stem Cells and Cloning: advances and applications, Auckland, v. 27, n. 7, p. 71-78, Aug. 2014.

VILLAFUERTE, R. Oryctolagus cuniculus. In: PALOMO, L.J.; GISBERT, J. (Ed).

Atlas de los mamíferos terrestres de España. dirección general de conservación de la naturaleza. Madrid: Secem-Secemv, 2002.

WANG, X. Y.; LAN, Y.; HE, W. Y.; ZHANG, L.; YAO, H. Y.; HOU, C. M.; TONG, Y.; LIU, Y. L.; YANG, G.; LIU, X. D.; YANG, X.; LIU,

B.; MAO, N. Identification of mesenchymal stem cells in aorta-gonad-mesonephros and yolk sac of human embryos. Blood, New York, v. 111, n. 4, p. 2436-2443, Feb. 2008.

WANG, Z. J.; AN, R. Z.; ZHAO, J. Z.; ZHANG, Q.; YANG, J.; WANG, J. B.; WEN, G. Y.; YUAN, X. H.; QI, X. W.; LI, S.J.; YE, X. Z. Repair of articular cartilage defects by tissue-engineered cartilage constructed with adipose-derived stem cells and acellular cartilaginous matrix in rabbits. Genetics and Molecular Research, Ribeirão Preto, v. 13, n. 2, p.4599-4606, June. 2014.

WEISSBERG, P. L.; QASIM, A. Stem cell therapy for myocardial repair, Heart, v. 91, n. 5, p. 696-702, June. 2005.

WENCESLAU, C. V.; MIGLINO, M. A.; MARTINS, D. S.; AMBROSIO, C. E.; LIZIER, N. F.; PIGNATARI, G. C.; KERKIS, I. Mesenchymal progenitor cells from canine fetal

tissues: yolk sac, liver, and bone marrow. Tissue Engineering: Part A, New York, v. 17, n. 18, p. 2164-2176, Sept. 2011.

WINCK, C. P. Estabelecimento e caracterização de células-tronco fetais de

membrana amniótica canina em diferentes estágios gestacionais. 2012. 74 f.

Dissertação (Mestrado em Ciências)- Faculdade de Medicina Veterinária e Zootecnia, Universidade de São Paulo, São Paulo, 2012.

WOLBANK, S.; PETERBAUER, A.; FAHRNER,S.; VAN GRIENSUEN, M.;

STADLER, G.; REDL, H.; GABRIEL, C. Dose-dependent immunomodulatory effect of human stem cells from amniotic membrane: a comparison with

human mesenchymal stem cells from adipose tissue. Tissue Engineering, New York, v. 13, n. 6, p. 1173–1183, June. 2007.

YOUNG, H.E. Existence of reserve quiescent stem cells in adults,

From amphibians to humans. Current Topics in Microbiology and Immunology, Berlin, v. 280, p. 71-109, 2004

ZHANG, W.; ZHANG, F.; SHI, H.; TAN, H.; HAN, S.; YE, G.; PAN, S.; SUN, F.; LIU, X. Comparisons of rabbit bone marrow mesenchymal stem cell isolation and culture methods in vitro. PLoS ONE, San Francisco, v. 9, n. 2, p. e88794, Feb. 2014. ZHANG, H.; IWAMA, M.; AKAIKE, T.; URRY, D. W.; PATTANAIK, A.; PARKER, T. M.; KONISHI, I.; NIKAIDO, T. Human amniotic cell sheet harvest using a novel temperature-responsive culture surface coated with protein-based polymer. Tissue Engineering, New York, v. 12, n. 2, p. 391-401, Feb. 2006.

ZHOU, S.; CHEN, J.; FENG, J. The effects of amniotic membrane on

polymorphonuclear cells. Chinese Medical Jornal, Pekinj, v. 116, n. 5, p. 788-790, May. 2003.

ZHU, X.; WANG, X.; CAO, G.; LIU, F.; YANG, Y.; LI, X.; ZHANG, Y.; MI, Y.; LIU, Y.; ZHANG, L. Stem cell properties and neural differentiation of sheep amniotic epithelial cells. Neural Regeneration Research, Shenyang, v. 8, n. 13, p .1210-1219, May. 2013.

Documentos relacionados