1. Os pacientes com câncer gástrico apresentaram maior frequência do gene cagA comparado aos pacientes com gastrite, estando associado com a evolução para câncer gástrico.
2. Pacientes infectados por cepas contendo o gene cagA apresentaram maior grau de inflamação e atividade neutrofílica, além de apresentarem maior associação com o desenvolvimento de metaplasia intestinal.
3. As cepas de H. pylori que apresentaram polimorfismo da região (EPIYA) considerado de alto risco foi predominante nos pacientes com câncer gástrico apresentando significância estatística positiva para o desenvolvimento desta doença.
4. Pacientes infectados por cepas de alto risco quanto ao polimorfismo da região EPIYA não mostraram associação com o aumento do grau de inflamação e atividade neutrofílica, contudo apresentou-se associado com o desenvolvimento de metaplasia intestinal.
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