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3. REVISÃO DE LITERATURA

6.1. Limitações do estudo

Estudos de casos retrospectivos são úteis no estudo de doenças ou eventos raros, entretanto várias limitações e vieses podem estar relacionados com esse tipo de estudo. O fato de o estudo incluir apenas um centro também pode ter contribuído para a formação de viés, entretanto, relatos de centros diferentes são importantes para aumentar o conhecimento da doença e seu tratamento, baseado em procedimentos agressivos e potencialmente críticos como a hemipelvectomia.

CONCLUSÕES

As principais conclusões deste estudo são:

1. Anestesia geral associada a bloqueio peridural foi a técnica anestésica mais utilizada nas cirurgias de hemipelvectomia analisadas.

2. O volume administrado de cristaloides e de concentrado de hemácias no intraoperatório, o tempo operatório e de internação hospitalar pós-cirurgia foram significativamente menores daqueles até então encontrados.

3. Dor aguda e crônica foram complicações importantes no período pós- operatório.

4. A hemipelvectomia externa foi mais prevalente que a interna e apresentou menor sobrevida em 60 meses, porém não houve diferença significativa entre os dados perioperatórios nas duas técnicas cirúrgicas.

5. O estágio avançado da doença dos pacientes estudados pode ter determinado o tempo médio reduzido de sobrevida após a cirurgia.

6. Apenas os estágios avançados 3 e 4 da doença foram preditores significativos para a redução da sobrevida após hemipelvectomia.

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