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1 VIII MitoMeeting 2015

On behalf of MitoMeeting organizing committee we are pleased to invite you to the 8th Annual Meeting of Mitochondria. The meeting will be held between the 07 and 10th of July 2015 in Guapé MG, Brazil. All participants will be stimulated to informally present their data in English as mini-oral presentations (10+5 min) or conferences (20+5 min). The scientific program is full of exciting issues. In addition, Guapé is surrounded by beautiful touristic places including the Paredão Water Falls, Farms, Escarpas do Lago, Furnas Lake, etc.

Organizing Committee:

Aníbal E. Vercesi – UNICAMP (anibal@unicamp.br) Helena Oliveira – UNICAMP (ho98@unicamp.br)

José Roberto Meyer Fernandes – UFRJ (meyer@bioqmed.ufrj.br) Antonio Galina – UFRJ (antoniogalina@yahoo.com.br)

Leonardo R Silveira –IB-UNICAMP (leors@unicamp.br) Gilberto Eiji Shiguemoto –UFSCAR (gileiji@gmail.com)

Logistics: Paulinho (UFRJ) and Cynthia (SBBq)

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2 SCIENTIFIC PROGRAMME

Tuesday – July 07th 19h Anibal E. Vercesi, FCM-UNICAMP

Welcome to the 2015 Mitomeeting 19:15 – 19:45 “Tribute to Leopoldo DeMeis”

Wagner Seixas, UFRJ

19:45 – 20:45 Leopoldo DeMeis Conference Lício Velloso, FCM-UNICAMP

The control of body adiposity - mitochondria and beyond.

Wednesday – July 08th - MORNING SECTIONS Chair: Alicia Kowaltowski – IQ-USP, São Paulo 09:00 - 09:20 h Alicia Kowaltowski, IQ-USP

Caloric restriction modulates insulin release by changing mitochondrial morphology and dynamics

09:25–09:35 h Julia Pellogia, IQ-USP

Impact of mitochondrial bioenergetics on skin aging 09:40–09:50 h Marcel Lara, IQ-USP

Mitochondrial ion transport in the brown adipose tissue 09:55–10:05 h Maria Fernanda Forni, IQ-USP

Mitochondrial dynamics determine stem cell fate 10:10–10:20 h Luis Alberto Luevano-Martinez, IQ-USP

Caloric restriction remodels mitochondrial membranes and cardiolipin Coffee break

Chair: Wagner Seixas Silva, UFRJ 10:35–10:55 h Wagner Seixas Silva, UFRJ

Thyroid states regulate subcelular glucose phosphorylation activity in rodents 11:00–11:10 h Diogo Noin de Oliveira, FCM-UNICAMP

Identification of oxidized lipids in mitochondria of non-obese diabetic mice 11:15 – 11:25

h

Cibele Zanardi Esteves, FCM-UNICAMP

Identification of high-fat compounds and extra virgin olive oil-supplemented diets in mouse liver extracts and isolated mitochondria using mass spectrometry 11:30 – 11:50

h

Rodrigo Catharino, FCM-UNICAMP

Parasitomics and mitochondia: Applications in mass spectrometry 11:55 – 12:05

h

Gabriela Souza, FCM-UNICAMP.

Inflammation-induced mitochondria dysfunction: interplay between IL-10 and TNF-alpha

LUNCH

Wednesday – July 08th - AFTERNOON SECTIONS Chair: Leonardo R Silveira – IB - UNICAMP 14:20 – 14:40h Leonardo R Silveira, IB-UNICAMP

Regulation of insulin response and mitochondrial function by Hypoxia-inducible fator 1 alpha (HIF1α)

14:45–14:55 h Tanes Lima, FMRP-USP

Network organization of mitochondrial biogenesis during C2C12 differentiation:

Who are the major players?

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3 Wednesday – July 08th - AFTERNOON SECTIONS

Chair: Leonardo R Silveira – IB - UNICAMP 15:00-15:10 h Carlos Sponton, IB-UNICAMP

Skeletal muscle crosstalk mediated by exosomes: a new paradigm in the control of mitochondrial function and insulin resistance

15:15–15:25 h Igor H. Sampaio, FMRP-USP

The role of mitochondrial membrane potential on mitochondrial function and insulin response in skeletal muscle cells

15:30–15:40 h Renato Branco , IB-UNICAMP

Protein malnutrition followed by diet-induced obesity programs mitochondrial metabolism and impairs taurine reestablishment of insulin secretion

15:45–15:55 h Nayara Leite, IB-Unicamp

Early protein malnutrition increases amplifying pathway of insulin secretion in obese mice

Coffee break Chair: Antonio Galina, UFRJ 16:10–16:30 h Tiago Rezende Figueira, USP-RP, Educação Física

The mitochondrial nicotinamide nucleotide transhydrogenase can be switched off during phosphorylating respiration in isolated liver mitochondria

16:30-16:40 h Anderson Teixeira Santos, UFRJ

Culture time has impact on mitochondrial physiology in L6 myoblast 16:45–16:55 h Gilberto Eiji Shiguemoto, UFSCAR

Ovarectomy and mitochondrial dysfunction in left ventricule fibers of rats 17:00–17:20 h Marcos Chiaratti, UFSCAR

Role of mitochondrial fusion in female fertility and in inheritance of mitochondrial DNA

17:25–17:35 h Carolina Macabelli, UFSCAR

Induced pluripotent stem cells derived from patients with MELAS A3243G as a model for studying mitochondrial inheritance

17:40-17:50 h Thiago Machado, UFSCAR

Transplantation of cytoplasm subjected to oxidative stress as a model for study of mitochondrial disease inheritance

DINNER NIGHT SECTIONS

Chair: Paulo Arruda – CBMEG - UNICAMP 20:00–20:10 h Pedro Barreto, CBMEG-UNICAMP

Plant Mitohormesis: Mitochondrial UCP1-induced hypoxia links altered carbon fixation and energy expenditure to increased stress tolerance in Nicotiana tabacum

20:15-20:25 h Renato Maia, CBMEG-UNICAMP

The effects on chloroplastic metabolism caused by the overexpression of mitochondrial UCP1 in plants

20:30–20:50 h Paulo Arruda, CBMEG-UNICAMP

How to design drought resistant plants based on mitochondrial metabolism manipulation

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4 THURSDAY – JULY 9th

MORNING SECTIONS

Chair: Roberto Docampo, University Georgia Athens and FCM-UNICAMP 09:00–09:30 h Roberto Docampo

Interactions of acidocalcisomes and mitochondria of trypanosomes 09:35–09:55 h Miguel Angel, Fapesp

Characterization of Trypanosoma cruzi mutant cell lines for overexpression and ablation of Mitochondrial Calcium Uniporter

10:00–10:20 h Noelia Lander, Fapesp

Gene silencing by CRISPR/Cas9 system for the study of Calcium homeostasis in Typanosoma cruzi

10:25–10:30 h Mayara Santos Bertolini, FCM-UNICAMP

Overexpression of MCU-I in T cruzi (Master´s degree project) 10:35–10:40 h Ana Patrícia Kutschat, Michigan University

Genetic encoded Ca2+ indicators (Summer training) Coffee break

Chair: Sérgio Akira Uyemura, FCFRP-USP 11:10–11:30 h Kildare Miranda, UFRJ

Asymmetric intra-organelar distribution of ions in the acidocalcisome:

implications on polyphosphate-cation complexes 11:35-11:45 h Vinicius Kannen, FCFRP-USPRP

Fluoxetine: an antidepressant acting against colon cancer.

11:50–12:00 h Mariana Figueiredo Rodrigues, UFRJ

Glycolytic and oxidative pathways in melanoma metastatic cells LUNCH

AFTERNOON SECTIONS

Chair: Ariel Silber, Dept Parasitology, ICB-USP 14:00–14:20 h Ariel Silber, ICB - USP

The role of amino acids in the energetic metabolism and oxidative imbalance in Trypanosoma cruzi.

14:25–14:35 h Brian Alejandro Suarez Mantilla, ICB-USP The role of proline in the diet of Trypanosomes 14:40–14:50 h María Julia Barisón, ICB-USP

The participation of Histidine in the bioenergetics of Trypanosoma cruzi 14:55–15:05 h Viviane Faiões, Fiocruz RJ (Research project)

Evaluation of new quinones derivatives as specific inhibitors of complex I, II or III in Leishmania infantum respiratory chain

15:10–15:20 h Ana Catarina Rezende, UFAL

Liver mitochondrial bioenergetics of the fish Liphiosurus alexandri (Pacamã) Coffee break

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5 THURSDAY – JULY 09th

AFTERNOON SECTIONS

Chair: Nadja C. de Souza Pinto, IQ-USP, São Paulo 16:00-16:20 h Nadja C. de Souza Pinto, IQ-USP

DNA repair defects in symptomatic and asymptomatic Alzheimer’s disease.

16:25–16:35 h Carolina Berra, IQ-USP

Mitochondrial (dys)function in cells lacking or overexpressing AAG.

16:40-16:50 h Daniela Cosentino Gomes, UFRJ

Nox4: a hydrogen peroxide-generating oxygen sensor 16:55–17:05 h Nathalia Rocco Machado, UFRJ

Possible sources of hydrogen peroxide generation stimulated by heme in Leishmania amazonenses

DINNER NIGHT SECTIONS

Chair: José Roberto Meyer Fernandes – UFRJ 20:00–20:20 h José Roberto Meyer Fernandes, UFRJ

Inorganic phosphate uptake in Trypanosoma brucei brucei 20:25–20:35 h Luiz Fernando Carvalho Kelly, UFRJ

Biochemical characterization of phosphate uptake in free-living Amoeba Acanthamoeba castellanii

FRIDAY – July 10th MORNING SECTION

Chair: Anibal E. Vercesi – FCM - UNICAMP 09:00–09:20 h Anibal E. Vercesi, FCM-UNICAMP

Forty years of Mitochondrial Permeability Transition 09:25–09:45 h Helena Oliveira Coutinho, IB-UNICAMP

Deficiency of mitochondrial nicotinamide nucleotide transhydrogenase (NNT) predisposes C57BL6 mice to metabolic syndrome

09:55–10:10 h Claudia Navarro, FCM-UNICAMP

Liver mitochondria isolated from nicotinamide transhydrogenase deficient mice are more sensitive than controls to dysfunctions induced by hiperlipdemic diets 10:15–10:35 h Anibal Vercesi Filho. Instituto Zootecnia, SP

Morro Dágua projet: Zebu cattle and Milk Casein A2A2 Early lunch: 11:30 hs

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6 List of participants

1. Alicia Kowaltowski – IQ – USP 2. Ana Catarina Rezende – UFAL 3. Ana Patrícia Kutschat – Michigan

University/Unicamp

4. Anderson Teixeira Santos – Master Student – UFRJ

5. Aníbal E. Vercesi – FCM-UNICAMP 6. Anibal Vercesi Filho – Instituto

Estadual de Zootecnia, SP 7. Antonio Galina – UFRJ

8. Ariel Silber – Dept Parasitology – ICB - USP

9. Brian Alejandro Suarez Mantilla - Post Doc - ICB - USP

10. Carlos Sponton – pos-doc - IB- UNICAMP

11. Carolina Berra – PhD student - IQ – USP

12. Carolina Macabelli - Master Student - UFSCAR

13. Cibele Zanardi Esteves – FCM – UNICAMP

14. Claudia Navarro – FCM - UNICAMP 15. Daniela Cosentino Gomes - Pos-doc

– UFRJ

16. Diogo Noin de Oliveira – FCM – UNICAMP

17. Eliana Araújo – FCM - UNICAMP 18. Gabriela Souza – Pos-doc – FCM -

UNICAMP

19. Gilberto Eiji Shiguemoto – UFSCAR 20. Helena Oliveira – IB-UNICAMP 21. Igor H. Sampaio – Master Student –

FMRP - USP

22. José Roberto Meyer Fernandes – UFRJ

23. Julia Pellogia – I.C. - IQ-USP, São Paulo.

24. Kildare Miranda - UFRJ

25. Leonardo R Silveira – IB-UNICAMP 26. Lício Velloso – FCM - UNICAMP

27. Luis Alberto Luevano-Martinez – IQ- USP

28. Luiz Fernando Carvalho Kelly – Master Student – UFRJ

29. Marcel Lara – I.C. – IQ – USP 30. Marcos Chiaratti - UFSCAR 31. Maria Fernanda Forni – IQ-USP 32. María Julia Barisón - Doutoranda -

ICB - USP

33. Mariana Figueiredo Rodrigues – Doctoral student – UFRJ

34. Mayara Santos Bertolini – FCM - UNICAMP

35. Miguel Angel – Pos-doc – FCM- UNICAMP

36. Nadja C. de Souza Pinto - IQ - USP 37. Nathalia Rocco Machado – Master

Stundent – UFRJ

38. Nayara Leite – IB – Unicamp 39. Noelia Lander – Pos-doc – FCM-

UNICAMP

40. Paulo Arruda - CBMEG - UNICAMP 41. Pedro Barreto, pos-doc – CBMEG –

UNICAMP

42. Renato Branco – IB – UNICAMP 43. Renato Maia, I.C - CBMEG -

UNICAMP

44. Roberto Docampo – Georgia University, Athens, FCM-UNICAMP 45. Rodrigo Catharino FCM - UNICAMP 46. Sérgio Akira Uyemura - FCFRP –

USP-RP

47. Tanes Lima - doutorando - FMRP- USP-RP

48. Thiago Machado - PhD Student - UFSCAR

49. Tiago Rezende Figueira – Ed. Física - USP-RP

50. Vinicius Kannen - PhD student - FCFRP – USP-RP

51. Viviane Faiões – Fiocruz - RJ 52. Wagner Seixas Silva – UFRJ

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7 Staff

53- Cynthia Bando, SBBq, SP 54- D. Delci, São Paulo (cozinha) 55- Paulinho, Rio de Janeiro, UFRJ 56- Fabiana, Guapé (cozinha/limpeza) 57- Sil Life – Gustavo

58- Sinc do Brasil - Juarez

59- 62 Equipe da Pousada do Lago (Everaldo, D. Cida, Juninho 1 e 2)

Thanks everyone for attending 2015 Mitomeeting and we looking forward to seeing you in 2016!

Organizing Committee

Referências

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