1 VIII MitoMeeting 2015
On behalf of MitoMeeting organizing committee we are pleased to invite you to the 8th Annual Meeting of Mitochondria. The meeting will be held between the 07 and 10th of July 2015 in Guapé MG, Brazil. All participants will be stimulated to informally present their data in English as mini-oral presentations (10+5 min) or conferences (20+5 min). The scientific program is full of exciting issues. In addition, Guapé is surrounded by beautiful touristic places including the Paredão Water Falls, Farms, Escarpas do Lago, Furnas Lake, etc.
Organizing Committee:
Aníbal E. Vercesi – UNICAMP (anibal@unicamp.br) Helena Oliveira – UNICAMP (ho98@unicamp.br)
José Roberto Meyer Fernandes – UFRJ (meyer@bioqmed.ufrj.br) Antonio Galina – UFRJ (antoniogalina@yahoo.com.br)
Leonardo R Silveira –IB-UNICAMP (leors@unicamp.br) Gilberto Eiji Shiguemoto –UFSCAR (gileiji@gmail.com)
Logistics: Paulinho (UFRJ) and Cynthia (SBBq)
2 SCIENTIFIC PROGRAMME
Tuesday – July 07th 19h Anibal E. Vercesi, FCM-UNICAMP
Welcome to the 2015 Mitomeeting 19:15 – 19:45 “Tribute to Leopoldo DeMeis”
Wagner Seixas, UFRJ
19:45 – 20:45 Leopoldo DeMeis Conference Lício Velloso, FCM-UNICAMP
The control of body adiposity - mitochondria and beyond.
Wednesday – July 08th - MORNING SECTIONS Chair: Alicia Kowaltowski – IQ-USP, São Paulo 09:00 - 09:20 h Alicia Kowaltowski, IQ-USP
Caloric restriction modulates insulin release by changing mitochondrial morphology and dynamics
09:25–09:35 h Julia Pellogia, IQ-USP
Impact of mitochondrial bioenergetics on skin aging 09:40–09:50 h Marcel Lara, IQ-USP
Mitochondrial ion transport in the brown adipose tissue 09:55–10:05 h Maria Fernanda Forni, IQ-USP
Mitochondrial dynamics determine stem cell fate 10:10–10:20 h Luis Alberto Luevano-Martinez, IQ-USP
Caloric restriction remodels mitochondrial membranes and cardiolipin Coffee break
Chair: Wagner Seixas Silva, UFRJ 10:35–10:55 h Wagner Seixas Silva, UFRJ
Thyroid states regulate subcelular glucose phosphorylation activity in rodents 11:00–11:10 h Diogo Noin de Oliveira, FCM-UNICAMP
Identification of oxidized lipids in mitochondria of non-obese diabetic mice 11:15 – 11:25
h
Cibele Zanardi Esteves, FCM-UNICAMP
Identification of high-fat compounds and extra virgin olive oil-supplemented diets in mouse liver extracts and isolated mitochondria using mass spectrometry 11:30 – 11:50
h
Rodrigo Catharino, FCM-UNICAMP
Parasitomics and mitochondia: Applications in mass spectrometry 11:55 – 12:05
h
Gabriela Souza, FCM-UNICAMP.
Inflammation-induced mitochondria dysfunction: interplay between IL-10 and TNF-alpha
LUNCH
Wednesday – July 08th - AFTERNOON SECTIONS Chair: Leonardo R Silveira – IB - UNICAMP 14:20 – 14:40h Leonardo R Silveira, IB-UNICAMP
Regulation of insulin response and mitochondrial function by Hypoxia-inducible fator 1 alpha (HIF1α)
14:45–14:55 h Tanes Lima, FMRP-USP
Network organization of mitochondrial biogenesis during C2C12 differentiation:
Who are the major players?
3 Wednesday – July 08th - AFTERNOON SECTIONS
Chair: Leonardo R Silveira – IB - UNICAMP 15:00-15:10 h Carlos Sponton, IB-UNICAMP
Skeletal muscle crosstalk mediated by exosomes: a new paradigm in the control of mitochondrial function and insulin resistance
15:15–15:25 h Igor H. Sampaio, FMRP-USP
The role of mitochondrial membrane potential on mitochondrial function and insulin response in skeletal muscle cells
15:30–15:40 h Renato Branco , IB-UNICAMP
Protein malnutrition followed by diet-induced obesity programs mitochondrial metabolism and impairs taurine reestablishment of insulin secretion
15:45–15:55 h Nayara Leite, IB-Unicamp
Early protein malnutrition increases amplifying pathway of insulin secretion in obese mice
Coffee break Chair: Antonio Galina, UFRJ 16:10–16:30 h Tiago Rezende Figueira, USP-RP, Educação Física
The mitochondrial nicotinamide nucleotide transhydrogenase can be switched off during phosphorylating respiration in isolated liver mitochondria
16:30-16:40 h Anderson Teixeira Santos, UFRJ
Culture time has impact on mitochondrial physiology in L6 myoblast 16:45–16:55 h Gilberto Eiji Shiguemoto, UFSCAR
Ovarectomy and mitochondrial dysfunction in left ventricule fibers of rats 17:00–17:20 h Marcos Chiaratti, UFSCAR
Role of mitochondrial fusion in female fertility and in inheritance of mitochondrial DNA
17:25–17:35 h Carolina Macabelli, UFSCAR
Induced pluripotent stem cells derived from patients with MELAS A3243G as a model for studying mitochondrial inheritance
17:40-17:50 h Thiago Machado, UFSCAR
Transplantation of cytoplasm subjected to oxidative stress as a model for study of mitochondrial disease inheritance
DINNER NIGHT SECTIONS
Chair: Paulo Arruda – CBMEG - UNICAMP 20:00–20:10 h Pedro Barreto, CBMEG-UNICAMP
Plant Mitohormesis: Mitochondrial UCP1-induced hypoxia links altered carbon fixation and energy expenditure to increased stress tolerance in Nicotiana tabacum
20:15-20:25 h Renato Maia, CBMEG-UNICAMP
The effects on chloroplastic metabolism caused by the overexpression of mitochondrial UCP1 in plants
20:30–20:50 h Paulo Arruda, CBMEG-UNICAMP
How to design drought resistant plants based on mitochondrial metabolism manipulation
4 THURSDAY – JULY 9th
MORNING SECTIONS
Chair: Roberto Docampo, University Georgia Athens and FCM-UNICAMP 09:00–09:30 h Roberto Docampo
Interactions of acidocalcisomes and mitochondria of trypanosomes 09:35–09:55 h Miguel Angel, Fapesp
Characterization of Trypanosoma cruzi mutant cell lines for overexpression and ablation of Mitochondrial Calcium Uniporter
10:00–10:20 h Noelia Lander, Fapesp
Gene silencing by CRISPR/Cas9 system for the study of Calcium homeostasis in Typanosoma cruzi
10:25–10:30 h Mayara Santos Bertolini, FCM-UNICAMP
Overexpression of MCU-I in T cruzi (Master´s degree project) 10:35–10:40 h Ana Patrícia Kutschat, Michigan University
Genetic encoded Ca2+ indicators (Summer training) Coffee break
Chair: Sérgio Akira Uyemura, FCFRP-USP 11:10–11:30 h Kildare Miranda, UFRJ
Asymmetric intra-organelar distribution of ions in the acidocalcisome:
implications on polyphosphate-cation complexes 11:35-11:45 h Vinicius Kannen, FCFRP-USPRP
Fluoxetine: an antidepressant acting against colon cancer.
11:50–12:00 h Mariana Figueiredo Rodrigues, UFRJ
Glycolytic and oxidative pathways in melanoma metastatic cells LUNCH
AFTERNOON SECTIONS
Chair: Ariel Silber, Dept Parasitology, ICB-USP 14:00–14:20 h Ariel Silber, ICB - USP
The role of amino acids in the energetic metabolism and oxidative imbalance in Trypanosoma cruzi.
14:25–14:35 h Brian Alejandro Suarez Mantilla, ICB-USP The role of proline in the diet of Trypanosomes 14:40–14:50 h María Julia Barisón, ICB-USP
The participation of Histidine in the bioenergetics of Trypanosoma cruzi 14:55–15:05 h Viviane Faiões, Fiocruz RJ (Research project)
Evaluation of new quinones derivatives as specific inhibitors of complex I, II or III in Leishmania infantum respiratory chain
15:10–15:20 h Ana Catarina Rezende, UFAL
Liver mitochondrial bioenergetics of the fish Liphiosurus alexandri (Pacamã) Coffee break
5 THURSDAY – JULY 09th
AFTERNOON SECTIONS
Chair: Nadja C. de Souza Pinto, IQ-USP, São Paulo 16:00-16:20 h Nadja C. de Souza Pinto, IQ-USP
DNA repair defects in symptomatic and asymptomatic Alzheimer’s disease.
16:25–16:35 h Carolina Berra, IQ-USP
Mitochondrial (dys)function in cells lacking or overexpressing AAG.
16:40-16:50 h Daniela Cosentino Gomes, UFRJ
Nox4: a hydrogen peroxide-generating oxygen sensor 16:55–17:05 h Nathalia Rocco Machado, UFRJ
Possible sources of hydrogen peroxide generation stimulated by heme in Leishmania amazonenses
DINNER NIGHT SECTIONS
Chair: José Roberto Meyer Fernandes – UFRJ 20:00–20:20 h José Roberto Meyer Fernandes, UFRJ
Inorganic phosphate uptake in Trypanosoma brucei brucei 20:25–20:35 h Luiz Fernando Carvalho Kelly, UFRJ
Biochemical characterization of phosphate uptake in free-living Amoeba Acanthamoeba castellanii
FRIDAY – July 10th MORNING SECTION
Chair: Anibal E. Vercesi – FCM - UNICAMP 09:00–09:20 h Anibal E. Vercesi, FCM-UNICAMP
Forty years of Mitochondrial Permeability Transition 09:25–09:45 h Helena Oliveira Coutinho, IB-UNICAMP
Deficiency of mitochondrial nicotinamide nucleotide transhydrogenase (NNT) predisposes C57BL6 mice to metabolic syndrome
09:55–10:10 h Claudia Navarro, FCM-UNICAMP
Liver mitochondria isolated from nicotinamide transhydrogenase deficient mice are more sensitive than controls to dysfunctions induced by hiperlipdemic diets 10:15–10:35 h Anibal Vercesi Filho. Instituto Zootecnia, SP
Morro Dágua projet: Zebu cattle and Milk Casein A2A2 Early lunch: 11:30 hs
6 List of participants
1. Alicia Kowaltowski – IQ – USP 2. Ana Catarina Rezende – UFAL 3. Ana Patrícia Kutschat – Michigan
University/Unicamp
4. Anderson Teixeira Santos – Master Student – UFRJ
5. Aníbal E. Vercesi – FCM-UNICAMP 6. Anibal Vercesi Filho – Instituto
Estadual de Zootecnia, SP 7. Antonio Galina – UFRJ
8. Ariel Silber – Dept Parasitology – ICB - USP
9. Brian Alejandro Suarez Mantilla - Post Doc - ICB - USP
10. Carlos Sponton – pos-doc - IB- UNICAMP
11. Carolina Berra – PhD student - IQ – USP
12. Carolina Macabelli - Master Student - UFSCAR
13. Cibele Zanardi Esteves – FCM – UNICAMP
14. Claudia Navarro – FCM - UNICAMP 15. Daniela Cosentino Gomes - Pos-doc
– UFRJ
16. Diogo Noin de Oliveira – FCM – UNICAMP
17. Eliana Araújo – FCM - UNICAMP 18. Gabriela Souza – Pos-doc – FCM -
UNICAMP
19. Gilberto Eiji Shiguemoto – UFSCAR 20. Helena Oliveira – IB-UNICAMP 21. Igor H. Sampaio – Master Student –
FMRP - USP
22. José Roberto Meyer Fernandes – UFRJ
23. Julia Pellogia – I.C. - IQ-USP, São Paulo.
24. Kildare Miranda - UFRJ
25. Leonardo R Silveira – IB-UNICAMP 26. Lício Velloso – FCM - UNICAMP
27. Luis Alberto Luevano-Martinez – IQ- USP
28. Luiz Fernando Carvalho Kelly – Master Student – UFRJ
29. Marcel Lara – I.C. – IQ – USP 30. Marcos Chiaratti - UFSCAR 31. Maria Fernanda Forni – IQ-USP 32. María Julia Barisón - Doutoranda -
ICB - USP
33. Mariana Figueiredo Rodrigues – Doctoral student – UFRJ
34. Mayara Santos Bertolini – FCM - UNICAMP
35. Miguel Angel – Pos-doc – FCM- UNICAMP
36. Nadja C. de Souza Pinto - IQ - USP 37. Nathalia Rocco Machado – Master
Stundent – UFRJ
38. Nayara Leite – IB – Unicamp 39. Noelia Lander – Pos-doc – FCM-
UNICAMP
40. Paulo Arruda - CBMEG - UNICAMP 41. Pedro Barreto, pos-doc – CBMEG –
UNICAMP
42. Renato Branco – IB – UNICAMP 43. Renato Maia, I.C - CBMEG -
UNICAMP
44. Roberto Docampo – Georgia University, Athens, FCM-UNICAMP 45. Rodrigo Catharino FCM - UNICAMP 46. Sérgio Akira Uyemura - FCFRP –
USP-RP
47. Tanes Lima - doutorando - FMRP- USP-RP
48. Thiago Machado - PhD Student - UFSCAR
49. Tiago Rezende Figueira – Ed. Física - USP-RP
50. Vinicius Kannen - PhD student - FCFRP – USP-RP
51. Viviane Faiões – Fiocruz - RJ 52. Wagner Seixas Silva – UFRJ
7 Staff
53- Cynthia Bando, SBBq, SP 54- D. Delci, São Paulo (cozinha) 55- Paulinho, Rio de Janeiro, UFRJ 56- Fabiana, Guapé (cozinha/limpeza) 57- Sil Life – Gustavo
58- Sinc do Brasil - Juarez
59- 62 Equipe da Pousada do Lago (Everaldo, D. Cida, Juninho 1 e 2)
Thanks everyone for attending 2015 Mitomeeting and we looking forward to seeing you in 2016!
Organizing Committee