Complete biallelic insulation at the H19/Igf2 imprinting control region position results in fetal growth retardation and perinatal lethality.

The KRT14 gene DNA methylation analysis was performed using Methylation-Specific PCR (MSP), and the KRT19 gene DNA methylation analysis was performed

Role of histone acetylation and DNA methylation in the maintenance of the imprinted expression of the H19 and Igf2 genes. Dean,

We quantified DNA methylation at imprinted gene DMRs in a large panel of human conceptal tissues, in matched buccal cell specimens collected at birth and at one year of age, and in

Taken together, these results suggest that elevated expression of H19/IGF2 is caused by a specific chromatin structure that is regulated by the DNA methylation status of IGF2 DMRs

Furthermore, besides considering changes in DNA methylation as mechanisms of disease, the role of epigenetics in general and DNA methylation in particular in

On the other hand, the lack of effects of maternal undernutrition on spleen growth in both male and female offspring with severe growth retardation in the current study

during ecodormancy break at late January (Figure 4 in Chapter IV) could be related to changes in DNA methylation, we analyzed the methylation pattern of a PrdCBF2 promoter region

With maturating differentiation the degree of methylation of the transcription factor binding sites in DNA isolated from the intermediate cell layers within the enhancer