Flagellin Encoded in Gene-Based Vector Vaccines Is a Route-Dependent Immune Adjuvant.

In the early stage of the disease, free antibodies to OspC and flagellin are measurable, whereas only later are responses to outer-surface protein A (OspA a

In the present study, a recombinant PCV2 Cap protein fused with flagellin was expressed in baculovirus expression system and the recombinant flagellin- Cap fusion protein was used

(2009) Protective HLA class I alleles that restrict acute-phase CD8+ T-cell responses are associated with viral escape mutations located in highly conserved regions of

In terms of T cell responses, we observed an early robust response to NS3 and NS4 (mostly CD4; data not shown), which was maintained at a lower level during chronic disease,

In the present study we investigated the flagellin-specific serum (IgG) and fecal (IgA) antibody responses elicited in BALB/c mice immunized with isogenic mutant derivatives

So, in this study, we examined the effect of aging on two crucial types of immune responses including mucosal immune responses in oral cavity and systemic

These results indicated that the three tested Salmonella flagellins are endowed with similar adjuvant effects toward immune responses mediated by activated antigen- specific CD8 +

For the present work, we evaluated the synergic serum immunoglobulin G (IgG) and fecal IgA antibody responses elicited in BALB/c mice who were intramuscularly primed with a DNA vaccine,