МИНИМАЛИЗАЦИИ ОБРАБОТКИ ПОЧВЫ ПОД ЯЧМЕНЬ И НУТ В ВОРОНЕЖСКОЙ ОБЛАСТИ

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-INTERNATIONAL RESEARCH JOURNAL

ISSN 2303-9868 PRINT

ISSN 2227-6017 ONLINE

№4 (35) 2015

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: editors@research-journal.org : www.research-journal.org

15.05.2015.

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XXXVIII

International Research Journal.

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- / PHYSICS AND MATHEMATICS 4

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/ BYOLOGY 12

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(IL-2, IL-7 IL-15) -IN VITRO ... 21

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/ ENGENEERING 28

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- / PHYSICS AND MATHEMATICS

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Karamova A.I.1,Petrov D.A.2

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Candidate of Physical and Mathematical Sciences, Bashkir State University

PARALLEL ALGORITHMS FOR LOCAL VARIATION METHOD FOR OPTIMAL CONTROL PROBLEMS

Abstract

The article describes the technology for solving the problem of optimal control in the form of parallel optimization processes with the choice of the best approximation. This algorithm is tested on test cases with known analytical solutions.

Keywords: optimal management, parallel technology.

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References

1. Verzhbickij V.M. Osnovy chislennyh metodov. - M.: Vysshaja shkola, 2002.

2. Kireev V.I., Panteleev A.V. Chislennye metody v primerah i zadachah. - M.: Vysshaja shkola, 2008.

3. Perepjolkin E.E., Sadovnikov B.I., Inozemceva N.G. Vychislenija na graficheskih processorah (GPU) v zadachah matematicheskoj i teoreticheskoj fiziki. - M.: URSS, 2014.

4. Sanders D., Kjendrot Je. Tehnologija CUDA v primerah. - M.: DMK Press, 2011.

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Prokhorova O.V.

Dr.Sci.Tech, docent,

Samara state university of architecture and civil engineering

METHOD OF THE PRIME NUMBERS SEQUENCE GENERATION

Abstract

The article describes the method of the prime numbers sequence generation. Author states necessary and sufficient conditions fo r prime and composite numbers. Solutions of the prime numbers generation with the verification required conditions and the decomposition of the composite number on the prime multipliers were shown.

Keywords: prime and composite numbers, generation of the prime numbers, set of the significant numbers.

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References

1. Prohorova O.V. Informacionnaja bezopasnost' i zashhita informacii: uchebnik. Samara: SGASU, 2014. – 114 s.

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Tikhomirov I.V.

PhD in Physics and mathematics, Omsk State Technical University

THE ABRIKOSOV VORTICES CONTAINING MULTIPLE FLUX QUANTA OF THE MAGNETIC FIELD

Abstract

In this paper, we investigated a single vortex in a thin superconducting film containing multiple flux quanta. Obtained the exact expression for the free energy of the vortex taking into account the distribution of the order parameter near the core of the vortex. It is shown that the merging of the vortices containing one quantum of flux, in a dense swirl of liquid.

Keywords: vortex liquid, superconducting film, the Abrikosov vortex, the superconductor of the second kind.

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References

1. De Zhen P.Sverhprovodimost' metallov i splavov. – M.: Mir, 1968. 2. Hu C.R., Phys.Rev. B, 6, 1972, p. 1756.

3. Shmidt V.V. Vvedenie v fiziku sverhprovodnikov. – M.:MCNMO, 2000.

/ BYOLOGY

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Vertiprahov V.G.1, Fomenko E.G.2, Bondarchuk M.L.3,

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Doctor of Biological Sciences, 2Candidate of BIological Sciences, Transbaikal State University, 3

Postgraduate, Institute of Veterinary Medicine of Eastern Siberia

(13)

13

Abstract

The article presents the results of experiments on pigs-weaners to study the effects of tissue slides prepared by V. P. Filatov from the pancreas and spleen, on the average daily weight gain on the background of the different density of the feed. The results indicate that the positive dynamics of mass gain observed in piglets in the experimental groups on the background miscapitalized diet and stunted due to functional insufficiency of the digestive system.

Keywords: pigs-weaners, low protein diet, the mass gain.

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References

1. Daricheva N. N., Ermolaev V. A. Tissue therapy in veterinary medicine: Monograph. – Ulyanovsk, UGSKHA, 2011. -168 S. 2. Kuznetsov V. K. Statistical processing of results of observations. //Vopr. Rheumatism. -1975. - No. 3. – S. 57-61.

3. Zubin I. N. Nonspecific mastitis in farm animals Zabaikalskogo region: Monograph/ I. N. Zubin, M. F. Zyubina, B. N. Gomboev, B. T. Garmaev, R. Z. Siraziev. – Chita, 2015. - 187 s.

4. Zubin I. N., Smirnov P. N., Naprimerov V. A. Mastitis in cattle: a study/ Zubin I. N., Smirnov P. N., Naprimerov V. A. - Novosibirsk, 2007 – 232 s.

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Kereya A.V.1, Bolshakov M.A.2, Zamoshchina T.A.3, Kutenkov O.P.4, Rostov V.V.5, Svetlik M.V.6, Khodanovich M.Y.7

1

Postgraduate student, 2Doctor of Biological Sciences, Professor, National Research Tomsk State University; 3Doctor of Biological Sciences, Professor, Siberian State Medical University; 4Lead Engineer, 5Doctor of Physical and Mathematical Sciences, Professor, Institute

of High Current Electronics Siberian Branch of the Russian Academy of Sciences 6

PhD in Biological Sciences, 7Doctor of Biological Sciences, Professor, National Research Tomsk State University

MOTOR ACTIVITY OF LABORATORY MICE AFTER NANOSECOND REPETITIVELY-PULSED MICROWAVE AND X-RAY IRRADIATION

Abstract

The purpose was to study the effect of nanosecond repetitive-pulsed microwaves (RPM) and X-ray on brain activity of mice. The effect was evaluated by the change of ten daily dynamics of general motor activity of mice. The experiments show that after the irradiation of the brain within 10 days of 4000 pulses every day of RPM (peak power density 1500 W/cm2) and X-ray (total dose of 1 Gy) physical activity changes non-monotonically. The effect depended on the type of electromagnetic radiation and the pulse repetition frequency.

Key words: repetitively-pulsed electromagnetic radiation, physical activity of mice.

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4. Akoev I.G., Pashovkina M.S., Dolgacheva L.P., Semenova T.P., Kalmykov V.L. Ferment activities of some tissues and blood of animals and man under action of microwaves and hypothesis about a possible role of free-radicals in mechanisms of the nonlinear effects and in the modifications on the affective animal behavior // RКНТКЭТШЧ ЛТШХШРв. RКНТШОМШХШРв. β00β. VШХ. 4β. № γ. S. γββ–330.

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References

1. Kereya A.V., Bol'shakov M.A., Zamshchina T.A., Knjazeva I.R., Kutenkov O.P., Semenova Ju.N. Povedencheskie i metabolicheskie reakcii laboratornyh myshej na vozdejstvie nanosekundnogo impul'sno-periodicheskogo mikrovolnovogo izluchenija na golovnoj mozg // Izvestija vysshih uchebnyh zavedenij. Fizika. 2014. T. 57. № 1β/β. S. 198–203

2. Kereya A.V., Bol'shakov M.A., Zamshchina T.A., Knjazeva I.R., Kutenkov O.P., Semenova Ju.N., Rostov V.V. O vlijanii nanosekundnogo impul'sno-periodicheskogo rentgenovskogo izluchenija na dejatel'nost' golovnogo mozga laboratornyh myshej // Vestnik Tomskogo gosudarstvennogo universiteta. β014. № γ79. S. β09–213.

3. Zhuravlev G.I. Izmenenija jelektrofiziologicheskih reakcij krolikov pri slabom jelektromagnitnom izluchenii // Fundamental'nye issledovanija. β008. № 6. S. β6–30.

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19

5. AНОв А.R. TТssЮО ТЧЭОrКМЭТШЧ аТЭС ЧШЧТШЧТгТЧР ОХОМЭШЦКРЧОЭТМ ПТОХНs // PСвsТМКХ RОЯТОа. 1981. VШХ.61. № β. P. 4γ5–514.

6. Bolshakov M.A., Alekseev S.I. Bursting responses of Lymnaea neurons to microwave radiation // Bioelectromagnetics. 1992. Vol. 13(2). P. 119–129.

7. Njagu A.I., Loganovskij K.N. Nejropsihiatricheskie jeffekty ionizirujushhih izluchenij // Izd.: Chornobil'interinform, 1997. 349s. 8. Pejmer S.I., Dudkin A.O., Sverdlov A.G. Neposredstvennoe dejstvie malyh doz radiacii na nejrony // Doklady AN SSSR. 1985. T.

β84. №6. S. 1481–1484.

9. Martin C., Martin S., Viret R., Denis J., Mirguet F., Diserbo M., Multon E., Lamproglou I. Low dose of the gamma acute radiation syndrome (1.5 Gy) does not significantly alter either cognitive behavior or dopaminergic and serotoninergic metabolism // Cellular and molecular biology. 2001. May, 47(3):459–65.

10. PrКЯТХК ЩrШЯОНОЧТУК rКЛШЭ Т ТsЩШХ'гШЯКЧТУК УОФsЩОrТЦОЧЭКХ'ЧвС гСТЯШЭЧвС»,ЮЭЯОrгСНОЧЧвО PrТФКгШЦ MГ SSSR № 775 ШЭ 1β КЯРЮsЭК

1977 g.; Hel'sinskaja Deklaracija Vsemirnoj Medicinskoj Associacii ot 1964 g., dopolnennaja v 1975, 1983 i 1989 gg; Euro guide on the accommodation and care of animals used for experimental and other scientific purposes, 2007, 17 s. www.felasa.eu.

11. Klimov A.I., Kovalchuk O.V., Rostov V.V., Sinyakov A.N. Measurement of Parameters of X-Band High-Power Microwave

SЮЩОrrКНТКЭТЯО PЮХsОs // IEEE TrКЧsКМЭТШЧs ШЧ PХКsЦК SМТОЧМ. β008. VШХ. γ6. № 6. P.1–4.

12. Artemov K.P., El'chaninov A.A., Kutenkov O.P., Rostov V.V., Turchanovskij I.Ju. Impul'sno-periodicheskij istochnik

rОЧЭРОЧШЯsФШРШ ТгХЮМСОЧТУК // PrТЛШrв Т ЭОСЧТФК УОФsЩОrТЦОЧЭК. β004. № 5. S. 67–68.

13. Suhanov D.Ja., Zelenskaja A.E.; Krivova N.A., Khodanovich M.Ju. Reklamno-tehnicheskoe opisanie // Programma ocenki

НЯТРКЭОХ'ЧШУ КФЭТЯЧШsЭТ Фrвs Я ШРrКЧТМСОЧЧШЦ ЩrУКЦШЮРШХ'ЧШЦ ЩrШsЭrКЧsЭЯО ЩШ МТПrШЯШЦЮ ЯТНОШТгШЛrКгСОЧТУЮ «MШЮsО EбЩrОss». TШЦsk, 2010. S. 1–4.

14. Krivova N.A., Khodanovich M.Ju., Zamoshchina T.A., i dr. Vlijanie dioksida titana na nekotorye funkcii central'noj nervnoj sistemy

Фrвs // VОsЭЧТФ TШЦsФШРШ РШsЮНКrsЭЯОЧЧШРШ ЮЧТЯОrsТЭОЭК. BТШХШРТУК. β011. № β (14). S. 96–109.

15. Zamoshchina T.A., Krivova N.A., Khodanovich M.Ju., Truhanov K.A., Tuhvatulin R.T., Zaeva O.B., Zelenskaja A.E., Gul' E.V. Vlijanie modeliruemyh gipomagnitnyh uslovij dal'nego kosmicheskogo poleta na ritmicheskuju organizaciju povedencheskoj aktivnosti krys

// AЯТКФШsЦТМСОsФКУК Т УОФШХШРТМСОsФКУК ЦОНТМТЧК. β01β.T. 46. № 1. S.17–23.

16. Pavlova L.N., Zhavoronkov L.P., Dubovik B.V., Glushakova V.S., Posadskaja V.M. Jeksperimental'naja ocenka reakcij CNS na

ЯШгНОУsЭЯТО ТЦЩЮХ'sЧвС JОMI ЧТгФШУ ТЧЭОЧsТЯЧШsЭТ // RКНТКМТУК Т rТsФ. β010. TШЦ 19. № γ. S. 104–119.

17. Bol'shakov M.A., Alekseev S.I. Vlijanie impul'snogo mikrovolnovogo obluchenija na jelektricheskuju aktivnost' nejronov molljuskov // Izvestija AN SSSR. Ser. biol., 1987. S. 312–314

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Novoselova E.I.1, Volkova O.O.2

1

Doctor of Biological Sciences, 2Postgraduate, Bashkirian State University

INFLUENCE OF LEAD AND ZINC ON THE ACTIVITY OF CATALASE ALLUVIAL MEADOW SOIL

Abstract

The work presents experimental data about the effect of different concentrations of lead and zinc in the catalase activity in a laboratory circumstances. The influence of lead in doses of 5, 10, 20, 40 mg / kg of soil, zinc - 50, 110, 220, 440 mg / kg on catalase of activity alluvial meadow soil. The enzyme activity was determined after 3, 90, 180, 360 days from the start of the experiment. An inverse relationship between the activity of catalase and a dose of lead and zinc is identified. The responsiveness of catalase to doses of the metals under the IMAC value is shown.

Keywords: heavy metals, pollution, lead, zinc, soil enzymes, catalase.

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References

1. Val'kov V.F., Kolesnikov S.I., Kazeev K.Sh. Vlijanie zagrjaznenija tjazhelymi metallami na fitotoksichnost' chernozema // Agrohimija. – 1997. – № 6. – S. 50-54.

2. Vodjanickij Ju.N. Formy cinka v zagrjaznennyh pochvah (obzor literatury) // Pochvovedenie. – 2010. –№γ. – S. 293-301. 3. Galliulin R.V., Galiulina R.A. Konceptual'naja model' fermentativnoj indikacii zagrjaznenija pochvy tjazhelymi me-tallami //

GОШУОФШХШРТМСОsФТО ЩrШЛХОЦв гКРrУКгЧОЧТУК ШФrЮгСКУЮ¬sССОУ srОНв ЭУКгСОХвЦТ ЦОЭКХХКЦТ. – Tula:TGU, 2006. – S. 100-104.

4. Egoshina T.L., Shihova L.N. Svinec v pochvah i rastenijah severo-vostoka evropejskoj chasti Rossii // Vestnik OGU. – 2008. –

№10. – S. 135-141

5. Zvjagincev D.G., Kurakov A.V., Umarov M.M., Filipp Z. Mikrobiologicheskie i biohimicheskie pokazateli zagrjaznenija svincom dernovo-podzolistoj pochvoj //Pochvovedenie. – 1997. –№9. – S. 1124-1131.

6. Kazeev K.Sh., Kolesnikov S.I., Val'kov V.F. Biologicheskaja diagnostika i indikacija pochv: metodologija i metody issledovanij. – Rostov n/D: RGU, 2003. – 216s.

7. Kamenshhikova V.I., Fedotova O.A. Vlijanie tjazhelyh metallov na biologicheskuju aktivnost' podzolistoj pochvy // Vestnik Permskogo universiteta. – 2004. –№β. – S. 163-165.

8. MКrПОЧТЧК τ.E. IгЦОЧОЧТО sЭrЮФЭЮrв ФШЦЩХОФsК ЦТФrШ¬sФШЩТМСОsФТС РrТЛШЯ ЩrТ гКРrУКгЧОЧТТ ЩШМСЯ ЭУКгСОХвЦТ ЦОЭКХХКЦТ // VОsЭЧТФ MGU. – 1985. – № β. – 46-50 s.

9. Mineev V.G. Jekologicheskie problemy agrohimii. – M.: MGU, 1988. – 284 s

10. Novoselova E.I., Bashkatov S.A. Vlijanie zagrjaznenija kadmiem na fermentativnuju aktivnost' chernozema obyknovennogo // Vestnik BashGU. – 2014. –№ 4. – S. 1204-1206.

11. Orientirovochno-dopustimye koncentracii (ODK) himicheskih veshhestv v pochve. Gigienicheskie normativy. Gn 2.1.7.2041-09. 12. Popova L.D. Kompleksnaja jekologo-himicheskaja ocenka i normirovanie kachestva pochvenno- rastitel'nogo pokrova gorodskih

УОФШsТsЭОЦ.КЯЭШrОП. НТs. …НШФЭ. ЛТШХ. ЧКЮФ. – Pertrozavodsk, – 2015. – 34s.

13. Rusanov A.M., Teslja A.V., Prihozhaj N.I., Turlibekova D.M. Soderzhanie valovyh i podvizhnyh form tjazhelyh metallov v pochvah g. Orska // Vestnik OGU. – 2012. – №4. – S. 226-230

14. Haziev F.H. Metody pochvennoj jenzimologii. – M.: Nauka, 2005. – 252 s.

15. Shhelchkova M.V., Struchkova L.K., Fedorov I.A. Kompleksnoe vlijanie tjazhelyh metallov na fermentativnuju aktivnost' i jeffektivnoe plodorodie merzlotnoj lugovo-chernozemnoj pochvy // Vestnik SVFU. – 2010. –№4. – S. 16-21.

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Sokhonevich N. A.1, Yurova K. A.2, Khaziakhmatova O. G.3, LТЭЯТЧШЯ L.S.4 1

Junior Researcher, 2Postgraduate student, 3Postgraduate student, 4Head of the Laboratory, Doctor of Medical Sciences, Immanuel Kant Baltic Federal University, Kaliningrad, Russia.

Work performed under the scholarship of the President of the Russian Federation (SP-454.2013.4) and subsidies for the implementation of puЛХТМ аШrФs "EstКЛХТsСЦОЧt ШП sМТОЧtТПТМ rОsОКrМС» (№θ0γ).

EFFECTS OF CYTOKINES (IL-2, IL-7 and IL-15) ON THE ACTIVATION PROCESS AND PROLIFERATION OF NAIVE T CELLS IN VITRO

Abstract

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peripheral healthy blood donors. In general, it was found that the in vitro effects of cytokines - rIL-2, rIL-7 and rIL-15, equally affect the activation process of naive CD4 + and CD8 + - T cell subpopulations which associating with CD69 and CD25 molecules expression.CD45RA + CD4 + T cells were resistant to the proliferative effect of rIL-2, rIL-7 and rIL-15 compared with CD45RA + CD8 + T lymphocytes.

Keywords: naive T cells, cytokines, activation, proliferation.

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rIL-β (1,0 / ), CD8+

( , γ0%) rIL-β ( . β).

, , CD4+ - in vivo in

vitro [9].

IL-15, IL-β, ,

. , IL-15 , IL-2 [10].

CD45RA+ - rIL-15, CD4+/CD8+CD69+

(1,0 / ).

. 1 – CD4+/CD8+CD69+ ( .) CD4+/CD8+CDβ5+ - ( .) (%) CD45RA+CDγ+ -

(23)

23

. 1 – CD4+/CD8+CD69+ ( .) CD4+/CD8+CDβ5+ - ( .) (%)

CD45RA+CDγ+ -

in vitro . r2_-

, CD4+_/CD8+_CD45RA+_CD25+_- _-

rIL-15 ( . 1). -

rIL-15, , , IL-2/IL-15R

.[11]. , CD45RA+CD8+ - rIL-15 – CD71+

- , , β

( . β).

. Alves N.L. . Д1βЖ

, IL-15 CD8+ - .

, IL-15 in vitro , IL-2 [13],

: - IL-15Rα IL-2/15R ,

- , , IL-15,

Д1βЖ.

IL-7, IL-β IL-15, - ДβЖ.

, rIL-7 CD69+ (r2=0,65, p<0,05) CD25+ (r2=0,72, p<0,05)

- ( . 1), , CD71 ( .β).

CD45RA+_CD8+_- _, _rIL-₇ _CD69+_T- ₍_r2_=0,80,

p<0,05). CD8+CD25+ CD8+CD71+ -rIL-7 (1,0 10-9 _{/ )}_.

. 2 – CD4+/CD8+CD71+ - (%) CD45RA+CDγ+ - in vitro

. r2-

IL-7 .

, in vivo IL-7 CD4+ CD8+ - .

, IL-7R- - ,

- Д14Ж. in vitro , - ,

, - Д15Ж,

(24)

CD45RA+ - , (CD25, CD71),

IL-7 α- IL-2R (CDβ5) - , , ,

Д17Ж.

, , in vitro rIL-2, rIL-7 rIL-15

CD4+ CD8+- - . CD45RA+CD4+ T- , CD45RA+CD8+ - , (rIL-2, rIL-7 rIL-15),

, in vivo in vitro.

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// . – 2014. - . 6. № 1. - . 7-26.

5. . . . . - .: - , 2010. - 752 c.

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17. . ., . . -β - // . –

2008. - №4. – . 515-521.

References

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2. Litvinova L.S., Sokhonevich N.A., Gutsol A.A. et al. Influence of Immunoregulatory Cytokines IL-2, IL-7 and IL-15 upon Activation, Proliferation and Apoptosis of Immune Memory T-cells in vitro // Cell and Tissue Biology. - 2013. - V. 7(6). - . 5γ9–544.

3. Huang W., August A. The signaling symphony: T cell receptor tunes cytokine-mediated T cell differentiation // J Leukoc Biol. – 2015. – V. 97(3). – P. 477-485.

4. Litvinova L.S., Gutsol A.A., Sokhonevich N.A. i dr. Osnovnye poverkhnostnye markery funktsional'noy aktivnosti T-limfotsitov // Meditsinskaya immunologiya. – 2014. - T. 6. № 1. - S. 7-26.

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