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Lecture Notes in Computational Vision

and Biomechanics

Volume 14

Series Editors

João Manuel R. S. Tavares, Porto, Portugal R. M. Natal Jorge, Porto, Portugal

Editorial Advisory Board Alejandro Frangi, Sheffield, UK Chandrajit Bajaj, Austin, USA Eugenio Oñate, Barcelona, Spain

Francisco Perales, Palma de Mallorca, Spain Gerhard A. Holzapfel, Stockholm, Sweden J. Paulo Vilas-Boas, Porto, Portugal Jeffrey A. Weiss, Salt Lake City, USA John Middleton, Cardiff, UK

Jose M. García Aznar, Zaragoza, Spain Perumal Nithiarasu, Swansea, UK Kumar K. Tamma, Minneapolis, USA Laurent Cohen, Paris, France

Manuel Doblaré, Zaragoza, Spain Patrick J. Prendergast, Dublin, Ireland Rainald Löhner, Fairfax, USA Roger Kamm, Cambridge, USA Shuo Li, London, Canada

Thomas J. R. Hughes, Austin, USA Yongjie Zhang, Pittsburgh, USA

For further volumes:

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The research related to the analysis of living structures (Biomechanics) has been a source of recent research in several distinct areas of science, for example, Mathematics, Mechanical Engineering, Physics, Informatics, Medicine and Sport. However, for its successful achievement, numerous research topics should be considered, such as image processing and analysis, geometric and numerical modelling, biomechanics, experimental analysis, mechanobiology and enhanced visualization, and their application to real cases must be developed and more investigation is needed. Additionally, enhanced hardware solutions and less invasive devices are demanded.

On the other hand, Image Analysis (Computational Vision) is used for the extraction of high level information from static images or dynamic image sequences. Examples of applications involving image analysis can be the study of motion of structures from image sequences, shape reconstruction from images and medical diagnosis. As a multidisciplinary area, Computational Vision considers techniques and methods from other disciplines, such as Artificial Intelligence, Signal Processing, Mathematics, Physics and Informatics. Despite the many research projects in this area, more robust and efficient methods of Computational Imaging are still demanded in many application domains in Medicine, and their validation in real scenarios is matter of urgency. These two important and predominant branches of Science are increasingly considered to be strongly connected and related. Hence, the main goal of the LNCV&B book series consists of the provision of a comprehensive forum for discussion on the current state-of-the-art in these fields by emphasizing their connection. The book series covers (but is not limited to):

• Applications of Computational Vision and Biomechanics

• Biometrics and Biomedical Pattern Analysis

• Cellular Imaging and Cellular Mechanics

• Clinical Biomechanics

• Computational Bioimaging and Visualization

• Computational Biology in Biomedical Imaging

• Development of Biomechanical Devices

• Device and Technique Development for Biomedical Imaging

• Digital Geometry Algorithms for Compu-tational Vision and Visualization

• Experimental Biomechanics

• Gait & Posture Mechanics

• Multiscale Analysis in Biomechanics

• Neuromuscular Biomechanics

• Numerical Methods for Living Tissues

• Numerical Simulation

• Software Development on Computational Vision and Biomechanics

• Grid and High Performance Computing for Computational Vision and Biomechanics

• Image-based Geometric Modeling and Mesh Generation

• Image Processing and Analysis

• Image Processing and Visualization in Biofluids

• Image Understanding

• Material Models

• Mechanobiology

• Medical Image Analysis

• Molecular Mechanics

• Multi-Modal Image Systems

• Multiscale Biosensors in Biomedical Imaging

• Multiscale Devices and Biomems for Biomedical Imaging

• Musculoskeletal Biomechanics

• Sport Biomechanics

• Virtual Reality in Biomechanics

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Shuo Li

João Manuel R. S. Tavares

Editors

Shape Analysis in Medical

Image Analysis

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Editors Shuo Li

GE Healthcare and University of Western Ontario London, ON Canada

João Manuel R. S. Tavares

Departamento de Engenharia Mecânica Faculdade de Engenharia, Universidade

do Porto Porto Portugal

ISSN 2212-9391 ISSN 2212-9413 (electronic) ISBN 978-3-319-03812-4 ISBN 978-3-319-03813-1 (eBook) DOI 10.1007/978-3-319-03813-1

Springer Cham Heidelberg New York Dordrecht London Library of Congress Control Number: 2013957553  Springer International Publishing Switzerland 2014

This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmissrion or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. Exempted from this legal reservation are brief excerpts in connection with reviews or scholarly analysis or material supplied specifically for the purpose of being entered and executed on a computer system, for exclusive use by the purchaser of the work. Duplication of this publication or parts thereof is permitted only under the provisions of the Copyright Law of the Publisher’s location, in its current version, and permission for use must always be obtained from Springer. Permissions for use may be obtained through RightsLink at the Copyright Clearance Center. Violations are liable to prosecution under the respective Copyright Law. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use.

While the advice and information in this book are believed to be true and accurate at the date of publication, neither the authors nor the editors nor the publisher can accept any legal responsibility for any errors or omissions that may be made. The publisher makes no warranty, express or implied, with respect to the material contained herein.

Printed on acid-free paper

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Preface

This book presents novel and cutting-edge topics in Advances of Shape Analysis in Medical Image Analysis in order to solidify knowledge in the related fields and define their key stakeholders.

The 13 chapters included in this book were written by invited experts of international recognition and address important issues in shape analysis in medical image analysis, including: techniques for image segmentation, registration, mod-elling and classification and applications in biology, cardiac, brain, spine, chest, lung, and clinical practice.

The book covers the most recent advances in this area. Therefore, this book is of crucial effectiveness for researchers, students, end-users, and manufacturers from several multidisciplinary fields, as the ones related with artificial intelligence, bioengineering, biomechanics, computational mechanics, computational vision, computer sciences, human motion, mathematics, medical imaging, imaging-based intervention, medicine, pattern recognition, and physics.

The editors would like to take this opportunity to thank all invited authors for sharing their works, experiences, and knowledge, making possible their dissemi-nation through this book.

Shuo Li João Manuel R. S. Tavares

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Contents

Part I Methods and Models

Shape Analysis for Brain Structures . . . 3 Bernard Ng, Matthew Toews, Stanley Durrleman and Yonggang Shi

Shape Analysis in Molecular Imaging . . . 51 Fei Gao and Pengcheng Shi

Variational Shape Representation for Modeling, Elastic

Registration and Segmentation. . . 95 Amal A. Farag, Ahmed Shalaby, Hossam Abd El Munim

and Aly Farag

Image Computing Based on Bayesian Models (BM) . . . 123 Zhong Xue and Stephen Wong

Shape-Constrained Deformable Models and Applications

in Medical Imaging. . . 151 Jürgen Weese, Irina Wächter-Stehle, Lyubomir Zagorchev

and Jochen Peters

Part II Application Cases

Accurate Pathology Segmentation in FLAIR MRI

for Robust Shape Characterization . . . 187 April Khademi, Alan R. Moody and Anastasios Venetsanopoulos

Groupwise Registration of Brain Images for Establishing

Accurate Spatial Correspondence of Brain Structures . . . 229 Zhenyu Tang and Yong Fan

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Modeling of Lung Nodules from LDCT of the Human Chest:

Algorithms and Evaluation for CAD Systems. . . 259 Amal A. Farag, Mostafa Farag, James Graham, Salwa Elshazly,

Mohamed al Mogy and Aly Farag

Analyzing the Shape and Motion of the Lungs and Heart

in Dynamic Pulmonary Imaging . . . 291 Jianming Liang, Tim McInerney and Demetri Terzopoulos

Epithelial Cell Segmentation via Shape Ranking. . . 315 Alberto Santamaria-Pang, Yuchi Huang, Zhengyu Pang, Li Qing

and Jens Rittscher

Computational Modeling of the Spine . . . 339 Tobias Klinder, Samuel Kadoury and Cristian Lorenz

Shape Constraints for the Left Ventricle Segmentation

from Cardiac Cine MRI Based on Snake Models. . . 373 Yuanquan Wang, Yuwei Wu and Yunde Jia

An Optical Flow Approach to Assessment of Ventricular Shape

Change Based on Echocardiography . . . 413 Vahid Tavakoli, Nirmanmoh Bhatia, Rita Longaker, Motaz Alshaher,

Marcus Stoddard and Amir A. Amini

Editors Biography. . . 441

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