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DOI:

10.1590/0004-282X20150018

ARTICLE

OPINION

Dengue and brain hemorrhage

Hemorragia cerebral e dengue

Dear editor,

he recent report on “Dengue and brain hemorrhage” is very

interesting

1

. Daher et al. reported an interesting case of difuse

brain hemorrhage in a dengue patient

1

. In fact, the brain hem

-orrhage in dengue is an interesting neurological complication

of dengue. An interesting namely expanded dengue syndrome

should be discussed. his condition is an extremely severe den

-gue presentation, it has the component of brain hemorrhage

and other unusual complications such as subacute thyroiditis

2

.

he challenge in management of intracranial hemorrhage due

to dengue is the profound thrombocytopenia. he resolution

of bleeding can be spontaneous in some cases

2

. However, in

the case with vital site bleeding, the consideration of surgical

management is needed. If there is no proper management, the

fatal outcome is common

3

. For those cases, the use of platelet

transfusion can be useful and the surgical managements usu

-ally provide good outcome

4

.

Beuy Joob

1

, Viroj Wiwanitkit

2

1Sanitation 1 Medical Academic Center, Bangkok Thailand; 2Hainan Medical University, China.

Correspondence: Beuy Joob; Sanitation 1 Medical Academic Center, Bangkok, Thailand; E-mail: beuyjoob@hotmail.com

Conflict of interest: There is no conflict of interest to declare.

Received 28 October 2014; Received in final form 03 December 2014; Accepted 23 December 2014.

References

1. Daher RT, Marussi VH, Pedroso JL, Oliveira AS, Amaral LL. Dengue virus infection presenting with diffuse brain hemorrhage. Arq Neuropsiquiatr. 2014;72(10):815. http://dx.doi.org/10.1590/0004-282X20140131 2. Assir MZ, Jawa A, Ahmed HI. Expanded dengue syndrome:

subacute thyroiditis and intracerebral hemorrhage. BMC Infect Dis. 2012;12:240. http://dx.doi.org/10.1186/1471-2334-12-240

3. Wiwanitkit V. Magnitude and pattern of neurological pathology in fatal dengue hemorrhagic fever: a summary of Thai cases. Neuropathology. 2005;25(4):398. http://dx.doi.org/10.1111/j.1440-1789.2005.00653.x 4. Kumar R, Prakash O, Sharma BS. Intracranial hemorrhage in dengue fever:

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