Avaliação da ação do uso tópico de heparina encapsulada em nanopartículas poliméricas recobertas com quitosana em modelo de úlcera de pele em ratos

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J KZ I P I Y O I N \ PV W M N J I OP Q O Q U I Y O M Y M J KQ ffffffffffffffffffffffffffffffffffffffffffffffffffffff   Ž †   ‚ ‹ ˆ • — š j M P L I Y O Q \ I U J M O Q U Q Y T M J Q SL I P Q J M N Q Y KU Q KN Y M P U Q KN I J KQ R v O KL M N J M N J KZ I P I Y O I N \ PV W M N J I OP Q O Q U I Y O M Y M N J KQ  fffffffffffffffffffffffffffffffffffffffffffffffffffff Ž †   ‚ ‹ ˆ • » š j M P L I Y O Q \ I U J M O Q U Q Y T M J Q SL I P Q J M N Q Y KU Q KN Y M P U Q KN I J KQ R v O KL M N J M N J KZ I P I Y O I N \ PV W M N J I OP Q O Q U I Y O M Y M J KQ   fffffffffffffffffffffffffffffffffffffffffffffffffffff  Ž †   ‚ ‹ ˆ • © š | M O M N J I V U Q Y KU Q S Y M P U Q S J M \ P V W M L M Y OP M SI OP Q O Q J M L M U \ I S W V P M ffffffffffffffffffffffffffffffffffffffffffffffffffffffffffffffffffffffffffffffffffffffffffffffffffffffffffffffff  Ž †   ‚ ‹ ˆ “ ” š | M O M N J I V U Q Y KU Q S Y M PU Q S J M \ P V W M  OP Q O Q J M L M U \ I S L M U I Y M } QW Q P KY Q SK` P I ffffffffffffffffffffffffffffffffffffffffffffffffffffffffffffffffffffffffffffffffffffffffffffffffffffffffffffffff ò Ž †   ‚ ‹ ˆ “ • š | M O M N J I V U Q Y KU Q S Y M P U Q S J M \ P V W M  OP Q O Q J M L M U \ I S L M Y O I Y J M Y Q Y W Q PO [L V SQ N ` Q w KQ N fffffffffffffffffffffffffffffffffffffffffffffffffffffffffffffffffffffffffffffffffffffff  Ž †   ‚ ‹ ˆ “ “ š | M O M N J I V U Q Y KU Q S Y M P U Q S J M \ P V W M  OP Q O Q J M L M U \ I S L M Y O I Y J M Y Q Y M W Q P O [L V SQ N L M U I Y M } Q W Q P KY Q fffffffffffffffffffffffffffffffffffffffffffffffffffffffffffffffffff  Ž †   ‚ ‹ ˆ “ ˜ š | M O M J Q S U KY Q L M P Q J Q L M U ó { I ` KJ I Y L KQ Y J M M N P I NV SO Q J M N J M N Q Y KU Q KN Y M P U Q KN OP Q O Q J M N L M U \ I S W V P M r L M Y OP M SI s ffffffffffffffffffffffffffffffffffffffffffffffffffffff  Ž †   ‚ ‹ ˆ “ ° š | M O M J Q S U KY Q L M P Q J Q L M U ó { I ` KJ I Y L KQ Y J M M N P I NV SO Q J M N J M N Q Y KU Q KN J KQ R v O KL M N OP Q O Q J M N L M U \ I S W V P M r L M Y OP M SI s ffffffffffffffffffffffffffffffffffffffffffffffffff  Ž †   ‚ ‹ ˆ “ ™ š | M O M N J Q N S U KY Q N L M P Q J Q N L M U ó { I ` KJ I Y L KQ Y J M M N P I NV SO Q J M N J M N Q Y KU Q KN Y M P U Q KN OP Q O Q J M N L M U \ I S L M Y O I Y J M I Y M } Q W Q P KY Q SK` P I fffffffffffffffffffff  Ž †   ‚ ‹ ˆ “ ´ š | M O M J Q S U KY Q L M P Q J Q L M U ó { I ` KJ I Y L KQ Y J M M N P I NV SO Q J M N J M N Q Y KU Q KN J KQ R v O KL M N OP Q O Q J M N L M U \ I S L M Y O I Y J M I Y M } Q W Q P KY Q SK` P I fffffffffffffffffffffffffffffff  Ž †   ‚ ‹ ˆ “ — š | M O M N J Q N S U KY Q N L M P Q J Q N L M U ó { I ` KJ I Y L KQ Y J M M N P I NV SO Q J M N J M N Q Y KU Q KN J M \ P V W M OP Q O Q J M L M U \ I S L M Y O I Y J M Y Q Y M W Q PO [L V SQ N ` Q w KQ N fffffffffffffff  Ž †   ‚ ‹ ˆ “ » š | M O M J Q S U KY Q L M P Q J Q L M U ó { I ` KJ I Y L KQ Y J M M N P I NV SO Q J M N J M N Q Y KU Q KN Y M P U Q KN OP Q O Q J M N L M U \ I S L M Y O I Y J M Y Q Y M W Q PO [L V SQ N L M U I Y M } Q W Q P KY Q ffffffffff 

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J KQ R v O KL M N J M N J KZI P I Y O I N \ P V W M N J I OP Q O Q U I Y O M fffffffffffffffffffffffffffffffffffffffffffff  Ž †   ‚ ‹ ˆ ° ˜ š y I NV SO Q J M N J Q Q O K` KJ Q J I J Q L Q O Q SQ N I Y M N Q Y KU Q KN Y M P U Q KN I J KQ R v O KL M N J M N J KZ I P I Y O I N \ PV W M N J I OP Q O Q U I Y O M fffffffffffffffffffffffffffffffffffffffffffffffffffffffffffffffffffff  Ž †   ‚ ‹ ˆ ° ° š  V P ` Q J I L Q SKR P Q b k M J Q J M N Q \ I U J I T KJ P M } KW P M SKY Q M R O KJ Q W M P U v O M J M L M SM P KU vOP KL M ffffffffffffffffffffffffffffffffffffffffffffffffffffffffffffffffffffffffffffffffffffffffffffffffff  Ž †   ‚ ‹ ˆ ° ™ š y I N V SO Q J M N J Q J M N Q \ I U J I T KJ P M } KW P M SKY Q Y M N Q Y KU Q KN Y M PU Q KN I J KQ R v O KL M N J M N J KZI P I Y O I N \ P V W M N J I OP Q O Q U I Y O M fffffffffffffffffffffffffffffffffffffffffffff 

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< @ A NO D H BO ? N N F ? NJ A N H > =J =A N C < N BG < K O < N L < K i J A K O ? =BK hD H BO ? N L ; =A N@ D H BO ? N < ? J OC ? N < =< @ < K O ? N H < =J =A C < N G ? N A K E J < N F ? <K H ? K OC A G ? N < @ K › @ < C ? M A C Bg M < = < G < h? C@ A OC A K N BO D C BA U a ? =G A C BL ^ . . . ` : V J =A W X Y Z [cL ^ . . _ b c : I B; ? G < C @ < ? J ; A K mH J =? A G B; ? N ? > A H A @ A G A @ A BN ; C ? hJ K G A G A ; < =< L < > h ? C@ A G A ; ? C =D d J =? N G < =B; D H BO ? N G < =B@ BO A G ? N ; ? C N < ; O ? N G < H ? =g E < K ? H ? @ M A N ? N N A K E J mK < ? N L =BK h g O BH ? N < K < C M ? N c œ N A G B; D H BO ? N N F ? A C C < G ? K G A G ? N < E C A K G < N L H ? K O < K G ? < @ N < J H BO ? ; =A N@ A J @ A E C A K G < i J A K O BG A G < G < =B; mG < ? N c œ J N ? G < h g C @ A H ? N ; ? C M BA O D ; BH A > @ J BO ? A OC A O BM ? L ; ? BN A => @ G ? OC A O A @ < K O ? G < G ? < K l A N H J O ” K < A N L K F ? > BK M A N BM ? L < ; < C @ BO < i J < @ < G BH A @ < K O ? N A d N ? CM BG ? N ; ? N N A @ A OJ A C K A A J N e K H BA G < @ < O A d ? =BV A l F ? I < ; g O BH A U   C A J NK BO V X Y Z [cL ^ . . ¡ bc   ? C < N O < @ ? O BM ? L A M BA G < A G @ BK BN OC A l F ? O D ; BH A O < @ N BG ? @ J BO ? BK M < NO BE A G A c / 0¢ 0 1 £ 7 ¤ 9 ¤ ¥¦ § 8 ¨ © ª ¦ « 2 ¤ ¬ 8 £ 3 7 3 £ ¤ ¬ 8 7 3 9 ¦ ª ¥ : A G @ BK BNOC A l F ? O D ; BH A G < @ < G BH A @ < K O ? N > H ? K OC ? =A G A ; ? C ; C ? ; C B< G A G < N A K A O k @ BH A N G A ; < =< U < Q c O B; ? G < ; < =< < A OJ A = H ? K G Bl F ? b L H A C A H O < C mNO BH A N G ? N hg C @ A H ? N U < Q c =B; ? h B=BH BG A G < b < A N H A C A H O < C mN O BH A N G A h ? C@ J =A l F ? U < Q c O A @ AK I ? G A ; A CO mH J =A b c ˜ Q BNO < @ d A N BH A @ < K O < ^ h? C @ A N G < ; < C@ < A l F ? G ? N h g C @ A H ? N K ? < NOC A O ? H D CK < ? f A C ? O A OC A K N < ; BG > C @ BH A < A C ? O A M BA ; ? C ? N c : h BE J C A ^ B=J NOC A < N O A N G J A N h ? C@ A N G < ; < C @ < A l F ? U ­ C ? @ @ < C < ® < J d < CO L ^ . . ¯ bc p qr s t u  w x € }u { z ut u u z y| y}t u ~  € ‚s }°| y u  y ‚ € ƒ z € {}€ { …u  uz }u  €  y ± qz z € „ v ² ‘ ³ ’ “

BK O < C H < =J =A C < < K M ? =M < A G BhJ N F ? G < @ ? => H J =A N A OC A M > N G A @ A OC BV =B; mG BH A < Q BNO < K O < < K OC < ? N H ? CK < D H BO ? N c : N C ? O A N OC A K N E =A K G J =A C < OC A K N h ? =BH J =A C O A @ d > @ H ? K OC Bd J < @ ; A C A A ; < K < OC A l F ? H J O ” K < A L K ? C @ A =@ < K O < < @ ; < i J < K A ; ? C H < K O A E < @ L H ? @ A ; < K A N . LR T G A ; < C@ < A l F ? O ? O A =L G < M BG ? š NJ A ; < i J < K A < Q O < K N F ? L N < K G ? BK N BE K Bh BH A K O < ; A C A A @ A B? C BA G A N h ? C @ J =A l ™ < N O D ; BH A N c ® ? < K O A K O ? L i J A K G ? N F ? J O B=BV A G A N h? C@ J =A l ™ < N @ BH C ? < K A K ? ; A CO BH J =A G A N L < NO A N C ? O A N ; ? G < @ G < N < @ ; < K I A C B@ ; ? C O A K O < ; A ; < = U: =M A C < V P ´ ? @ A K X Y Z [cL ^ . . ¡ b c : N E =” K G J =A N N < d g H < A N N F ? @ A BN ; < C@ < g M < BN i J < ? N H ? CK < D H BO ? N < ? N h g C @ A H ? N ; ? G < @ A =H A K l A C A G < C @ < A OC A M > N G ? h? =mH J =? L ; A N N A K G ? ; < =A E = ”K G J =A N < d g H < A L ? J ; < K < OC A K G ? K ? < ; BO > =B? ; < =A d A BK I A h? =BH J =A C U µ A C C W L ^ . . R b c ® ? < NOJ G ? h < BO ? ; ? C : =M AC < V P´ ? @ g K X Y Z [\ U^ . . ¡ b N ? d C < A ; < K < OC A l F ? G < K A K ? ; A CO mH J =A N ; ? =B@ > C BH A N < @ ; < =< G < ; ? C H ? L h ? B G < @ ? K N OC A G ? A OC A M > N G < @ BH C ? N H ? ; BA H ? K h ? H A = G < M A C C < G J C A A [Z ¶ X · L i J < A =? H A =BV A l F ? G A N K A K ? ; A C O mH J =A N > G < ; < K G < K O < G ? O A @ A K I ? c : N K A K ? ; A CO mH J =A N G < @ < K ? C G B”@ < OC ? L <@ O ? C K ? G < ^ . K @ L h BH A C A @ A H J @ J =A G A N K A N C < E B™ < N h ? =BH J =A C < N L < K i J A K O ? A N K A K ? ; A C O mH J =A N @ A B? C < N L < @ O ? C K ? G < ¸ ¹ ¹ º » ¼ ½¾ ¿ À » Á º  ¾ º ÿ À Ä À Å º ¾ Å Æ ÅÇ È ¾ Å É Ä À Ê Á ÈÁ ¼ Á º Ë ¾ Ì ¾ Ç Í Á Á Í ÎÄ Ï º  ÎÀ Ä Á À Ð Å ¾ ¿ Ñ Ë ¾ =? K E < G A N C < E B™ < N h ? =BH J =A C < N c / 0Ò 0 Ó 4 ¬ 3 § 8 ¥ 3 Ô ¤ 8 Õ 3 ¦ 3 ¥ : N › =H < C A N N F ? G < h BK BG A N H ? @ ? ? C ? @ ; B@ < K O ? G A < NOC J OJ C A A K A O k @ BH A K ? C @ A = < A ; < C G A G A hJ K l F ? G ? O < H BG ? A =O < C A G ? c Ö g A H J C A G A N › =H < C A N > J @ G BK ” @ BH ? < H ? @ ; =< Q ? ; C ? H < N N ? L i J < C < NJ =O A < @ NJ A C < NO A J C A l F ? A K A O k @ BH A < hJ K H B? K A = U • A V A CJ N X Y Z [cL R × × ¡ bc : H J C A G A N › =H < C A N K ? C @ A =@ < K O < ? H ? CC < G < J @ A @ A K < BC A < h BH B< K O < H A C A H O < C BV A G A ; ? C i J A OC ? h A N < N G BNO BK O A N f I < @ ? NO A N BA L BK h =A@ A l F ? L ; C ? =Bh< C A l F ? < C < @ ? G < =A @ < K O ? c ® A ; < =< K ? C @ A =L < N O < ; C ? H < N N ? G < H J C A > BK BH BA G ? =? E ? A ; D N A BK  › C BA c ØK BH BA =@ < K O < L ? H ? CC < J @

J @ A J @ < K O ? G A ; < C @ < A d B=BG A G < H A ; B=A C c Ù BA K O < G < NO A @ A B? C ; < C @ < A d B=BG A G < L ? N H ? @ ; ? K < K O < N G ? N A K E J < < Q OC A M A N A @ ; A C A ? =? H A = G A BK  › C BA L < A N ; =A i J < O A N A ? < K OC A C < @ H ? K O A O ? H ? @ ? N < =< @ < K O ? N G A @ A OC BV < Q OC A H < =J =A C =Bd < C A @ H BO ? H BK A N < hA O ? C < N G A H ? A E J =A l F ? L H A C A H O < C BV A K G ? A h A N < G < I < @ ? NO A N BA L BK h =J < K H BA K G ? K A BK h B=OC A l F ? G < =< J H D H BO ? N ; < =A =Bd < C A l F ? G < h A O ? C < N i J B@ B? O g O BH ? N c : BK h=A @ A l F ? BK BH BA = ? H ? C C < H ? @ A @ BE C A l F ? G ? N K < J OC D h B=? N A ? =? H A = G A BK  › C BA C < A =BV A K G ? A h A E ? H BO ? N < G < @ A O < C BA BN < NOC A K I ? N L C < NO ? N H < =J =A C < N < d A H O > C BA N L N < K G ? H A C A HO < C BV A G ? ; ? C < C BO < @ A L < G < @ A < G ? C c ˜ NO A @ BE C A l F ? H < N N A A ; D N A =E J K N G BA N L < @ O ? C K ? G < ^ P S G BA N G A BK  › C BA L N < A h < C BG A K F ? < NO BM <C H ? K O A @ BK A G A c : => @ G ? @ A BN L ? N K < J OC D h B=? N A E < @ H ? @ ? i J B@ B? A OC A O BM ? N ; A C A ? J OC A N H > =J =A N i J < < NO F ? < K M ? =M BG A N K A h A N < BK h=A @ A O D C BA U – A H Ú A W < – B==< C L ^ . . - b c : ; C ? Q B@ A G A @ < K O < - G BA N A ; D N A BK  › C BA L ? N @ A H C D hA E ? N < K OC A @ K A g C < A =< N B? K A G A < H ? K O BK J A @ ? ; C ? H < N N ? G < h A E ? H BO ? N < < @ H J C N ? c œ N @ A H C D h A E ? N A ; C < N < K O A @ M g C BA N hJ K l ™ < N BK H =J BK G ? A G < h < N A G ? I ? N; < G < BC ? L ; C ? @ ? l F ? < C < N ? =J l F ? G A BK h=A @ A l F ? L C < @ ? l F ? G A N H > =J =A N A ; ? ; O D O BH A N L N J ; ? C O < ; A C A A ; C ? =Bh < C A l F ? H < =J =A C U; C D Q B@ A h A N < G A H BH A OC BV A l F ? b < C < NO A J C A l F ? G ? O < H BG ? A ; D N A BK  › C BA c ˜ =< N ; C ? @ ? M < @ A N mK O < N < G < K J @ < C ? N ? N h A O ? C < N G < H C < N H B@ < K O ? H ? @ ? f ­ n a PÛ ¼ ­ n a P Ü ¼ Ý Þ Ý ¼ ß à Þ Ý Á á â Þ Ý ¼ ? N i J A BN N F ? C < N; ? K N g M < BN ; < =A ; C ? =Bh < C A l F ? H < =J =A C < A N mK O < N < G < @ ? => H J =A N G A @ A OC BV < Q OC A H < =J =A C U´ < BK — < < ž ? C E L ^ . R ^ b c Ö g A h A N < ; C ? =Bh < C A O BM A BK BH BA PN < H ? @ A @ BE C A l F ? G < hBd C ? d =A NO ? N < A G < ; ? N Bl F ? G < J @ A K ? M A @ A OC BV < Q OC A H < =J =A C N ? d ? H ? K OC ? =< G < H BO ? H BK A N C < E J =A O D C BA N H ? @ ? Øa ® Pã Á ­ n a P Û L H ? @ A N < H C < l F ? G < M g C BA N N J d NO ” K H BA N d g N BH A N K < H < N N g C BA N ; A C A A H BH A OC BV A l F ? L BK H =J BK G ? ; C ? O < ? E =BH A K ? N L g H BG ? I BA =J C k K BH ? < E =BH ? N A @ BK ? E =BH A K ? N L ; C BK H B; A =@ < K O < ? H ? =g E < K ? < h Bd C ? K < H O BK A c ˜ NO A i J A K O BG A G < G < H ? =g E <K ? > ? i J < G < O < C @ BK A A h? C l A G < O < K N F ? G A › =H < C A < C < ; C < N < K O A A d A N < ; A C A J @ A K ? M A @ A OC BV G < O < H BG ? H ? K < H O BM ? ; A C A ?

< C < NO A J C A l F ? G A M A N H J =A OJ C A U Ù BE < =@ A K K < ˜ M A K N L ^ . . ¡ ` ´ < BK — < < ž ? C E L ^ . R ^ bc œ O < H BG ? G < E C A K J =A l F ? > H A C A H O < C BV A G ? ; ? C J @ A A =O A G < K N BG A G < G < h Bd C ? d =A NO ? N L E C AK J =D H BO ? N L @ A H C D h A E ? N L H A ; B=A C < N L < h < BQ < N G < H ? =g E < K ? hC ? J Q A @ < K O < ? C E A K BV A G ? N L G < M BG ? š NJ A E C A K G < i J A K O BG A G < G < H ? @ ; ? K < K O < N H < =J =A C < N > H I A @ A G ? G < O < H BG ? G < E C AK J =A l F ? c ­ A @ d > @ L H ? @ ? A A K E B? E e K < N < K F ? < NO g H ? @ ; =< O A @ < K O < hBK A =BV A G A A BK G A L < NO < O < H BG ? > A =O A @ < K O < M A N H J =A C L ; ? C BN N ? d < @ A M < C @ < =I A G ? U´ < BK — < < ž ? C E L ^ . R ^ bc : A K E B? E e K < N < > ? O < C@ ? J O B=BV A G ? ; A C A A h ? C@ A l F ? G < K ? M ? N M A N ? N N A K E J mK < ? N A ; A CO BC G < M A N ? N ; C > P< Q BNO < K O < N L ; A C A C < H ? K < H O A C A ; < C hJ N F ? K J OC BO BM A c ä J @ ; C ? H < N N ? i J < < K M ? =M < H > =J =A N <K G ? O < =BA BN L h Bd C ? d =A NO ? N L @ A H C D h A E ? N < A @ A OC BV < Q OC A H < =J =A C c œ N @ A H C D hA E ? N ; C ? G J V < @ h A O ? C < N G < H C < N H B@ < K O ? ; A C A < NO B@ J =A C A A K E B? E e K < N < < A @ A OC BV < Q OC A H < =J =A C > J @ C < N < C M A O D C B? G < hA O ? C < N ; C D P A K E B? E e K BH ? N i J < N F ? =Bd < C A G ? N G J C A K O < A G < E C A G A l F ? ; C ? O < ? =mO BH A h < BO A ; < =A N H > =J =A N < K G ? O < =BA BN L G BN N ? =M < K G ? A =” @ BK A d A N A =L N < K G ? < NO A N L H A ; A V < N G < ; C ? =Bh< C A C < @ BE C A C ; A C A A g C < A G A BK  › C BA c œ ; C B@ < BC ? ; A N N ? ; A C A A h ? C @ A l F ? G < K ? M ? N M A N ? N L > A =BE A l F ? G ? N h A O ? C < N G < H C < N H B@ < K O ? A ? N C < H < ; O ? C < N G A N H > =J =A N < K G ? O < =BA BN G < M A N ? N < Q BNO < K O < N L AO BM A K G ? A N N B@ A H A N H A O A G < N BK A =BV A l F ? BK OC A H < =J =A C c œ N d C ? O ? N C < H > @ PH ? K N O BOJ mG ? N h ? C@ A @ ; < i J < K ? N H AK A BN OJ d J =A C < N i J < N < κ à Á ¿ ÈÎå À »  ¾ » ¾ Ç Ã¿ ¾ Å ½ ¾ ¿ » À º Ä ¾ Ç » Æ ÈÀ Ñ ¾ Ä Á Í À Å ¾ Å É æ ß ¾ Åà Á ¿ ξ ¿» Á º à Á ¼ ¾ Å º ¾ Í ¾ Å Í À Å ¾ Å Å Á OC A K N h ? C@ A @ < @ A CO >C BA N < M e K J =A N < h BH A @ @ A G J C ? N ; < =A < NO A d B=BV A l F ? G < NJ A N ; A C < G < N A OC A M > N G ? C < H CJ O A @ < K O ? G < ; < C D H BO ? N < H > =J =A N @ J N H J =A C < N =BN A N c a BK A =@ < K O < L ? h =J Q ? N A K E J mK < ? H ? @ ; =< O A ? ; C ? H < N N ? A K E B? E e K BH ? U – ? C E A K < ® BE A K L ^ . R - ` ´ < BK — < < ž ? C E L ^ . R ^ b c ® < NO A h A N < L ? K › @ < C ? G < hBd C ? d =A NO ? N @ A G J C ? N > C < G J V BG ? ; < =A G Bh < C < K H BA l F ? < @ @ B? hBd C ? d =A N O ? N L A h B@ G < ; C ? @ ? M < C A H ? K OC A l F ? G A h < C BG A L G B@ BK J BK G ? A N N B@ ? N < J O A @ A K I ? L < ; ? C hB@ L O < C @ BK A @ H ? @ H ? K N < H J O BM A A ; ? ; O ? N < c

h BN B? =D E BH A N c ç J A K G ? ? N O < H BG ? N N ? hC < @ BK  › C BA L ? N h Bd C ? d =A NO ? N O ? C K A @ P N < AO BM ? N < N < G Bh< C < K H BA @ < @ @ B? hBd C ? d =A NO ? N L ? N i J A BN ; C ? G J V < @ H ? K OC A l ™ < N < A O BM A @ A ; C ? G J l F ? G < ; C ? O < mK A N G A @ A OC BV < Q OC A H < =J =A C ; A C A hA H B=BO A C ? h < H I A @ < K O ? G A BK  › C BA c œ N hBd C ? d =A NO ? N N F ? H > =J =A N hJ N Bh ? C@ < N L < A @ ; =A @ < K O < G BNOC Bd J mG ? N K A @ A B? C BA G ? N O < H BG ? N L < @ < N ; < H BA = K ? N O < H BG ? N H ? K < H O BM ? N c : G Bh< C < K H BA l F ? G < hBd C ? d =A N O ? N < @ @ B? h Bd C ? d =A NO ? N > J @ < M < K O ? H I A M < K A h ? C@ A l F ? G ? O < H BG ? H ? K < H O BM ? G A H BH A OC BV A l F ? c a < K ? O B; BH A @ < K O < L ? N @ B? h Bd C ? d =A NO ? N N F ? H > =J =A N BK O < C @ < G Bg C BA N < K OC < hBd C ? d =A NO ? N < H > =J =A N G < @ › N H J =? =BN ? c ˜ =< N BK BH BA @ N < J A ; A C < H B@ < K O ? K A hA N < BK BH BA = G A h ? C @ A l F ? G ? O < H BG ? G < E C A K J =A l F ? < < Q ; C < N N A @ Ü P A H O BK A G < @ › N H J =? =BN ? L J @ @ A C H A G ? C G < G Bh< C < K H BA l F ? G A N H > =J =A N @ J N H J =A C < N =BN A N L i J < ; ? G < N < C J O B=BV A G ? ; A C A NJ A BG < K O Bh BH A l F ? U • B < è A K E L ^ . R R bc   ? C h B@ L < NO A @ A OC BV > ? C E A K BV A G A L H ? K NO BOJ BK G ? < K O F ? L A hA N < G < C < @ ? G < =A @ < K O ? L i J < ? H ? C C < G ? G BA ^ R P R A K ? A ; D N A BK  › C BA L ? K G < ? H ? CC < A N J d NO BOJ Bl F ? G ? H ? =g E < K ? O B; ? Ø Ø Ø ; < =? H ? =g E < K ? O B; ? Ø U@ A BN h? C O < b < ? C B< K O A G ? < @ ; < i J < K ? N h< BQ < N ; A C A =< =? N c œ H ? CC < A ; ? ; O ? N < G A N H > =J =A N G ? O < H BG ? G < E C A K J =A l F ? L G B@ BK J Bl F ? G ? ; C ? H < N N ? A K E B? E e K BH ? < h =J Q ? N A K E J mK < ? < A A O BM BG A G < @ <O A d D =BH A G A =< N F ? G B@ BK J B < h BK A =@ < K O < H < N N A U ´ < BK — < < ž ? C E L ^ . R ^ bc   ? C O A K O ? L ; A C A ? ; C ? H < N N ? G < H BH A OC BV A l F ? K ? C@ A = N F ? K < H < N N g C B? N M g C B? N < M < K O ? N H < =J =A C < N < @ A C H A G ? C < N d B? =D E BH ? N c   ? C > @ L < Q BNO < @ H ? K G Bl ™ < N ; A O ? =D E BH A N i J < C < NJ =O A @ < @ hBd C ? N < < › =H < C A N K F ? PH J C A G A N c ® < N O < H A N ? L < NO < < h BH B< K O < ; C ? H < N N ? > ; < C G BG ? L < A N › =H < C A N h BH A @ H C ? K BH A @ < K O < BK h =A @ A G A N L < NO A G ? H A C A H O < C BV A G ? ; < =A BK h B=OC A l F ? < Q H < N N BM A G < K < J OC D h B=? N L A N N ? H BA G ? š N < N ; > H B< N C < AO BM A N G < ? Q BE e K B? < < K V B@ A N G < N OC J mG A N U Ù B< E < =@ A K K < ˜ M A K N L ^ . . ¡ b c

I B; < C E =BH < @ BA L C < N; ? K N g M < = ; < =? G A K ? < @ H > =J =A N H ? @ J @ d A BQ ? Yé · ê ëì í X · L H ? @ ? ? N K < J C k K B? N c ˜ NO A A K ? C@ A =BG A G < > A H A J N A G < A =E J @ A N G A N H ? @ ; =BH A l ™ < N O A C G BA N G A @ A K Bh < NO A l F ? G ? G BA d < O < N L H ? @ ? › =H < C A N H J O ” K < A N < A K ? C @ A =BG A G < N M A N H J =A C < N L G < H ? CC < K O < N G A G BN hJ K l F ? G ? N BNO < @ A K < CM ? N ? AJ O k K ? @ ? L C < NJ =O A K G ? < @ < NO A N < M A N H J =A C < d A BQ A H BH A OC BV A l F ? U– BNI C A X Y Z [cL ^ . . _ b c : N › =H < C A N G < ; > < @ G BA d > O BH ? N A; C < N < K O A @ J @ A BK H BG e K H BA G < R S T c : K < J C ? ; A O BA L A H BC H J =A l F ? ; ? d C < < A NJ N H < ; O Bd B=BG A G < A BK h < H l ™ < N H ? K OC Bd J < @ ; A C A ? G < N < K M ? =M B@ < K O ? G ? ; > G BA d > O BH ? L H A C A H O < C BV A G ? ; ? C G < h? C @ BG A G < N L J =H < C A l ™ < N < BK h< H l F ? c   ? C N < OC A O A C G < J @ A G ? < K l A N BN O e @ BH A A N N ? H BA G A š < N O A N < =? H A =L > B@ ; ? C O A K O < ? ; C ? H < N N ? G < A K E B? E e K < N < K A =< N F ? L A h B@ G < i J < ? BK mH B? G ? ; C ? H < N N ? G < H BH A OC BV A l F ? ; ? N N A N < G < N < K M ? =M < C U – ? I A @ @ A G X Y Z [cL ^ . . _ bc / 0î 0 ï 3 2 8 § ¤ 9 8 : I < ; A C BK A O < @ N BG ? J O B=BV A G A I g G > H A G A N K A ; C g O BH A H =mK BH A H ? @ ? A K O BH ? A E J =A K O < L O A K O ? K ? OC A O A @ < K O ? H ? @ ? K A ; C ? h B=A Q BA G A OC ? @ d ? N < c – J BO ? N < NOJ G ? N N ? d C < A I < ; A C BK A @ ? NOC A @ N < J ; A ; < = K A BK Bd Bl F ? G A H A N H A O A G < H ? A E J =A l F ? L @ A N G A G ? N @ A BN C < H < K O < N O < @ N < J h ? H ? A @ ; =BA G ? L BK H =J BK G ? NJ A N A l ™ < N A K O BP BK h=A @ A O D C BA N c ž J A A l F ? A K O BP BK h =A @ A O D C BA ; C ? M > @ G A BK O < CM < K l F ? K ? N ; A N N ? N P H I A M < G ? C < H C J O A @ < K O ? G ? N =< J H D H BO ? N G A M A N H J =A OJ C A ; A C A A g C < A G A BK  › C BA L ; < =A H A; A H BG A G < G < @ ? G J =A C A Ø • P ¯ L A i J A = O < @ J @ < h < BO ? C < E J =A O D C B? N ? d C < ? J OC A N H BO ? H BK A N BK h=A @ A O D C BA N L ; < =A BK A O BM A l F ? G < H BO ? H BK A N ; C D P BK h=A @ A O D C BA N H ? @ ? ? ­ ® a P Ü ¼ Å Á ÈÁ  à κ À Å Å Á  ¿ Á à À Ä À Å Ê ¾ ¿ ÈÁ Ç Â ð  Îà ¾ Å Â ¾ » ¾ ñ à P R R d L BK O < E C BK A N H ? @ ? ? ò : – P R L < A O < K J A l F ? G A A O BM A l F ? G ? H ? @ ; =< @ < K O ? c : => @ G BN N ? L I g J @ < h < BO ? A K E B? E e K BH ? G < C BM A G ? G A BK O < C A l F ? H ? @ ? ó ˜ n a < H ? @ hA O ? C < N G < HC < N H B@ < K O ? G ? N h Bd C ? d =A NO ? N U ´ A M B— J @ A C X Y Z [cL ^ . . ¯ bc

I < ; A C BK A K F ? hC A H B? K A G A L ; < =A NJ A @ A B? C d B? G BN; ? K Bd B=BG A G < L @ A B? C M BG A P@ > G BA L @ A B? C C < =A l F ? A K O BPõ A Ÿ A K O BP ØØ A L < @ < K ? C G < N < K M ? =M B@ < K O ? G < ; =A i J < O ? ; < K BA BK G J V BG A ; < =A I < ; A C BK A U´ AM B— J @ A C X Y Z [cL ^ . . ¯ b c : < K ? Q A ; A C BK A > J @ A I < ; A C BK A G < d A BQ ? ; < N ? @ ? =< H J =A C < @ ; C < E A G A K ? OC A O A @ < K O ? G A ­ ó   L < h? B J O B=BV A G A K ? G < N < K M ? =M B@ < K O ? G < NO < ; C ? < O ? c p qr s t u ö w ÷ {}ts }s t u  u ø yz utq| u  y ù uqú € z y { € ƒ € „y ‚s „ut ˜ NOJ G ? N @ ? NOC A C A @ i J < A ô µ   – > H A ; A V G < BK Bd BC A A G < N F ? G < =<J H D H BO ? N ; ? =B@ ? C h ? K J H =< A C < N š N H > =J =A N < K G ? O < =BA BN < G B@ BK J BC A < Q ; C < N N F ? G < @ ? => H J =A N G < A G < N F ? H < =J =A C K A N › =H < C A N G < H ? CC <K O < N G A ­ ó   c ˜ @ A G Bl F ? L A G B@ BK J Bl F ? G A C < N; ? NO A BK h=A @ A O D C BA BK BH BA = H A J N A G A ; < =A ô µ   – ; ? G < N < C G < M BG ? š @ < K ? C BK M A N F ? G < @ A H C D hA E ? N K A BK  › C BA ` I g C < =A O ? N G < BK G J l F ? G < A ; ? ; O ? N < G < h Bd C ? d =A NO ? N L B@ ; ? C O A K O < ; C ? H < N N ? K A hA N < hBK A = G A H BH A OC BV A l F ? L H ? @ ? J @ @ < H A K BN@ ? I ? @ < ? NO g O BH ? A hB@ G < @ A K O < C A ; ? ; J =A l F ? H < =J =A C < N; < C A G A K ? N O < H BG ? N =< N B? K A G ? N Uò BM < =< — X Y Z [cL ^ . . o b Ù < M BG ? A < NO A N H A C A H O < C mNO BH A N L A ô µ   – ; ? G < N < C J O B=BV A G A K ? OC A O A @ <K O ? G < › =H < C A N H C k K BH A N G < G Bh < C < K O < N < O B? =? E BA N c ´ A M B— J @ A C X Y Z [\ U ^ . . ¯ b < NOJ G A C A @ ? J N ? G A ô µ   – ; A C < K O < C A = < @ ; A H B< K O < N H ? @ i J < B@ A G J C A G < ^ . A - S T G A NJ ; < C hmH B< H ? C ; ? C A = c œ N N < J N C < N J =O A G ? N @ ? NOC A C A @ i J < K ? E C J ; ? OC A O A G ? H ? @ ô µ   – I ? J M < G B@ BK J Bl F ? G ? < G < @ A < < C BO < @ A < @ S G BA N L A J @ < K O ? G A C < < ; BO < =BV A l F ? L G B@ BK J Bl F ? G A ؕ P ¯ < C < H ? K NO BOJ Bl F ? O ? O A = G ? O < H BG ? < @ ^ _ G BA N L H ? @ G B@ BK J Bl F ? G ? N N BK A BN H BH A OC BH BA BN c ® ? < NOJ G ? h < BO ? ; ? C Ú J N < µ B< K — B<û BH V U ^ . . ¯ b h ? B ? d N < CM A G ? ? < h < BO ? G A ô   µ – N J d H J O ” K < A < @ C A O ? N A ; D N J @ A BK H BN F ? G < ¡ H @ K ? G ? C N ? c ˜ NO < N A K B@ A BN h? C A @ G BM BG BG ? N

C < H < d BA N ? =J l F ? N A =BK A < ? N < E J K G ? C < H < d BA ô   µ – c ® ? N < E J K G ? E C J ; ? h? B H ? K N O A O A G ? ? A J @ < K O ? G A H ? K H < K OC A l F ? G < H ? =g E <K ? L @ ? NOC A K G ? A N N B@ ? < h < BO ? ; ? N BO BM ? G A ô   µ – K ? OC A O A @ < K O ? G < h < C BG A N G A ; < =< c ˜ @ ? J OC ? < N OJ G ? h < BO ? ; ? C Ú û < ? K X Y Z [c U ^ . . - b h? B M < C BhBH A G A A A l F ? G A i J BO ? N A K A N ? =› M < = < @ g E J A Uè ž ò b < G ? H ? @ ; =< Q ? I < ; A C BK A < i J BO ? N A K A N ? =› M < = < @ g E J A Uè ž ò Ÿ ò ô b L H ? @ ? A H < =< C A G ? C < N G ? ; C ? H < N N ? G < H BH A OC BV A l F ? < @ C A O ? N c : ; D N J @ A BK H BN F ? K ? G ? C N ? G < R LS H @ L ? N A K B@ A BN h ? C A @ G BM BG BG ? N < @ - E C J ; ? N f H ? K OC ? =< UE C J ; ? R bL è ž ò U E C J ; ? ^ b < H ? @ ; =< Q ? è ž ò Ÿ ò ô U E CJ ; ? - b c ­ ? G ? N ? N E C J ; ? N h ? C A @ A M A =BA G ? N A ; D N R S G BA N G A =< N F ? c œ E CJ ; ? H ? K OC ? =< O BK I A J @ h < C B@ < K O ? H ? @ A @ A C E < @ d < @ G < hBK BG A < C < H ? d < C O A ; ? C J @ A H C ? N O A c œ E C J ; ? ^ A ; C < N < K O ? J J @ h < C B@ < K O ? G < @ < K ? C O A @ A K I ? H ? @ G B@ BK J Bl F ? G A H C ? NO A < @ A C E < K N @ A =PG < h BK BG A N L A ; A C < K O A K G ? J @ A C < E < K < C A l F ? A ; A CO BC G A @ A C E < @ c œ E CJ ; ? - @ ? NOC ? J J @ A =< N F ? @ J BO ? ; C D Q B@ A G A H J C A G ? h < C B@ < K O ? c œ N H ? C O < N I BNO ? =D E BH ? N @ ? NOC A C A @ i J < K ? E C J ; ? - I ? J M < A C < E < K < C A l F ? i J A N < H ? @ ; =< O A G A N < NOCJ OJ C A N G ? N A K < Q ? N ; C < N < K O < N < @ J @ A G < C @ < K ? C @ A =L < K i J AK O ? i J < K ? E C J ; ? H ? K OC ? =< < K ? E C J ; ? ^ I ? J M < A A J N e K H BA < G B@ BK J Bl F ? G ? K › @ < C ? G < < NOC J OJ C A N A K < Q A N K A ; < =< L C < N ; < H O BM A @ < K O < UÚ û < ? K X Y Z [cL ^ . . - bc : A ; =BH A l F ? NJ d H J O ” K < A G A I < ; A C BK A > =B@ BO A G A ; < =A G ? C L BK A O BM A l F ? G ? h g C @ A H ? < @ R ^ A ^ ¡ I ? C A N L < C BN H ? N H ? @ ? N A K E C A @ < K O ? L OC ? @ d ? H BO ? ; < K BA L C < A l ™ < N G < I B; < C N < K N Bd B=BG A G < < ? NO < ? N; ? C ? N < c Ù < M BG ? A O ? G ? N < N N < N h A O ? C < N L A ô µ   – A ; =BH A G A O ? ; BH A @ < K O < L OC A V A ; ? N N Bd B=BG A G < G < G B@ BK J BC ? N C BN H ? N ? d N < C M A G ? N ; ? C @ < B? G A A ; =BH A l F ? NJ d H J O ” K < A c œ N < h < BO ? N ? d N < C M A G ? N G ? J N ? O D ; BH ? G < ô µ   – N F ? f ; C ? ; C B< G A G < N A K O BPBK h=A @ A O D C BA N L A =mM B? G A G ? C L ; C ? O < l F ? H < =J =A C L K < ? A K E B? E e K < N < L C < M <C N F ? G A < NO A N < L < ; BO < =BV A l F ? L C < NO A J C A l F ? G ? H ? =g E < K ? < H BH A OC BV A l F ? G A ; < =< U´ A M B— J @ A C X Y Z [cL ^ . . ¯ ` µ A CC < O ? X Y Z [c ^ . R . b c

@ A B? C < N i J < - S . Ù A L < L ; ? CO AK O ? L A ; < K < OC A l F ? G < ô µ   – > @ J BO ? d A BQ A L G < M BG ? A ? N < J ; < N ? @ ? =< H J =A C @ A B? C U - P × — Ù A b L I BG C ? hB=BH BG A G < < H A C E A K < E A O BM A U ž ? K E < Ú B@ L ^ . . ¯ bc Ø NO ? ; ? G < N < C @ BK B@ BV A G ? A OC A M > N G A < K H A ; NJ =A l F ? G A I < ; A C BK A < @ K A K ? ; A C O mH J =A N ; ? =B@ > C BH A N L ; C ? @ ? M < K G ? J @ A ; < K < OC A l F ? A G < i J A G A G < NO < H ? @ ; ? N O ? K A ; < =< L < O A @ d > @ A @ A K J O < K l F ? G ? ; C BK H m; B? A O BM ? K ? =? H A = G A A ; =BH A l F ? c / 0ü 0 ý ¤ ¥ ¦ 3 7 8 ¥ £ 3 4¤Õ 3 § 8 ¨ © ª ¬ ª 9 ¦ § ª 4 8 £ 8 3 9 8 9 ª 2 8 § ¦ þ ¬ 6 4 8 ¥ 2 ª 4¤ 7 ÿ § ¤ ¬ 8 ¥ : N K A K ? ; A C O mH J =A N ; ? =B@ > C BH A N h ? C A @ BK OC ? G J V BG A N K ? @ < C H A G ? H ? N@ > O BH ? < @ R × × S ; < =A • œ C < A = U – ò ­ L ^ . R . bc ˜ NO A N ; A CO mH J =A N N F ? N BNO < @ A N H A C C < A G ? C < N G < hg C @ A H ? N i J < A ; C < N < K O A @ G B” @ < OC ? BK h < C B? C A R
@ c œ O < C@ ? K A K ? ; A CO mH J =A BK H =J B A N K A K ? H g ; NJ =A N < A N K A K ? < N h < C A N L A N i J A BN G Bh< C < @ < K OC < N B N < E J K G ? A H ? @ ; ? N Bl F ? < ? C E A K BV A l F ? < NOC J OJ C A = U h BE J C A ¡ b c : N K A K ? H g ; N J =A N N F ? H ? K NO BOJ mG A N ; ? C J @ BK M D =J H C ? ; ? =B@ > C BH ? G BN; ? NO ? A ? C < G ? C G < J @ K › H =< ? ? =< ? N ? L ; ? G < K G ? ? h g C @ A H ? < NO A C G BN N ? =M BG ? K < NO < K › H =< ? < Ÿ ? J A G N ? C M BG ? š ; A C < G < ; ? =B@ > C BH A c   ? C ? J OC ? =A G ? L A N K A K ? < N h < C A N L i J < K F ? A ; C < N < K O A @ D =< ? < @ NJ A H ? @ ; ? N Bl F ? L N F ? h? C @ A G A N ; ? C J @ A @ A OC BV ; ? =B@ > C BH A L ? K G < ? h g C@ A H ? ; ? G < h BH A C C < O BG ? ? J A G N ? C M BG ? U ž H I A h hA V BH — X Y Z [cL ^ . . - bc p qr s t u ³ w x yz t y {y| }u ~  € y { s yƒ }q‚ u  y | u| € ‚ z {s „u { y | u| € y {yt u { z € „qƒ tq‚ u {w u’ tƒ u ‚ €  q{{ € „ q  € | € |  ‚ „y € € „y € {€  u { | u| € ‚ z {s „u {  ù ’ tƒ u ‚ € u  {€ t q € z ut y  y z € „qƒ tq‚ u  u { | u| € ‚ z {s „u { ‚’ tƒ u ‚ € t y}q € | u ƒ u}tq‡ z € „qƒ tq ‚ u  u { | u| € y {yt u {   ’ tƒ u ‚ € u  {€ t q  € € s q {z yt { € ƒ € „y ‚s „utƒ y| } y | u ƒ u}tq‡ z € „qƒ tq ‚ u  u { | u| € y {yt u { … ‚ø u u‡ q‚ ‰ Š ‹ Œ“    ö’ “

N J d NO ” K H BA N A O BM A N > B@ ; ? C O A K O < ; A C A A =O < C A C A N ; C ? ; C B< G A G < N h mN BH ? Pi J m@ BH A N L hA H B=BO A K G ? L ; ? C < Q < @ ; =? L NJ A ; < K < OC A l F ? K A ; < =< c : N K AK ? ; A C O mH J =A N ; ? =B@ > C BH A N ; A C A J N ? d B? =D E BH ? N F ? ; C <; AC A G A N H ? @ ; ? =m@ < C ? N d B? H ? @ ; A O mM < BN < d B? G < E C A G g M < BN c ˜ Q BNO < @ M g C B? N @ > O ? G ? N C < =AO A G ? N K A =BO < C A OJ C A ; A C A A ; C < ; A C A l F ? G < K A K ? ; A C O mH J =A N ; ? =B@ > C BH A N c @ G < N N < N @ > O ? G ? N > d A N < A G ? K A ; ? =B@ < C BV A l F ? ê ¶ Yé G < @ ? K k @ <C ? N G BN; < C N ? N H ? @ ? ? H BA K ? A H C B=A O ? G < A =i J B=A c œ J OC ? @ > O ? G ? d A N < BA PN < K A ; C < H B; BO A l F ? G < ; ? =m@ < C ? N ; C > P h ? C @ A G ? N L O A BN H ? @ ? ; ? =BUg H BG ? =g O BH ? b U   • : bL ; ? =BUg H BG ? =g O BH ? P H ? Pg H BG ? E =BH D =BH ? b U   • n : b L ; ? =BU

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PH A ; C ? =A H O ? K A b U   ò • b < L A BK G A L ? N H ? ; ? =m@ < C ? N G ? g H BG ? @ < O A H C m=BH ? < G < > NO < C A H C m=BH ? ? J @ < O A H C m=BH ? c ØK G < ; < K G < K O < @ < K O < G ? @ > O ? G ? G < ; C < ; A C A l F ? L ? N ; C ? G J O ? N h BK A BN N F ? ? d O BG ? N H ? @ ? NJ N; < K N ™ < N H ? =? BG A BN A i J ? N A N U ž H I A h h A V BH — X Y Z [cL ^ . . - bc : N K AK ? ; A C O mH J =A N ; ? =B@ > C BH A N O e @ A H A C A H O < C mNO BH A G < =Bd < C A l F ? NJ NO < K O A G A i J < M < @ A OC A BK G ? A A O < K l F ? G ? N ; < N i J BN A G ? C < N ; ? C ; C ? ; ? C H B? K A C J @ A A =O < C K A O BM A A OC A O BM A ; A C A J @ A =Bd < C A l F ? ; ? C =? K E ? ; < C m? G ? G < A E < K O < N O < C A; e J O BH ? N c œ N N BNO < @ A N G < =Bd < C A l F ? ? h <C < H < @ BK › @ < C A N M A K O A E < K N i J A K G ? H ? @ ; A C A G ? N A ? J OC ? N G < G ? N A E < K N H ? K M < K H B? K A BN L O A BN H ? @ ? f R b @ A B? C < hBH g H BA O < C A ; e J O BH A L H ? @ =Bd < C A l F ? ; C ? E C < N N BM A < H ? K OC ? =A G A G ? h g C @ A H ? ` ^ b G B@ BK J Bl F ? N BE K Bh BH A O BM A G A O ? Q BH BG A G < < @ A B? C O < @ ; ? G < ; < C@ A K e K H BA K A H BC H J =A l F ? ` - b K A OJ C < V A < H ? @ ; ? N Bl F ? G ? N M < mH J =? N L A => @ G < ; C ? O < l F ? H ? K OC A @ < H A K BN@ ? N G < BK NO A d B=BG A G < < G < H ? @ ; ? N Bl F ? G ? h g C@ A H ? UBK A O BM A l F ? ; C < @ A OJ C A b ` ¡ b A G @ BK BNOC A l F ? N < E J C A L @ BK B@ BV A K G ? ? J A d ? =BK G ? C < A l ™ < N BK h=A @ A O D C BA N =? H A BN ` S b G B@ BK J Bl F ? G ? K › @ < C ? G < G ? N < N G < M BG ? š =Bd < C A l F ? ; C ? E C < N N BM A ` ¯ b ; ? N N Bd B=BG A G < G < G BC < H B? K A @ < K O ? A A =M ? N < N; < H mhBH ? N UÙ J C A K X Y Z [cL ^ . R . b c @ A g C < A i J < O < @ N BG ? @ J BO ? BK M < NO BE A G A > A A ; =BH A l F ? O D ; BH A G < K A K ? ; A CO mH J =A N L ; ? C A J @ < K O A C ? ; ? G < C G < ; < K <OC A l F ? G < h g C @ A H ? N ? J @ ? => H J =A N d B? A O BM A N c : => @ G BN N ? L h ? B H =A C A @ < K O < G < @ ? K NOC A G ? i J < A N K A K ? ; A CO mH J =A N ; ? =B@ > C BH A N N F ? H A ; A V < N G < @ ? G Bh BH A C