Ubiquitin ligase RNF123 mediates degradation of heterochromatin protein 1α and β in lamin A/C knock-down cells.

Human Scribble (Vartul) Is Targeted for Ubiquitin- Mediated Degradation by the High-Risk Papillomavirus E6 Proteins and the E6AP Ubiquitin- Protein Ligase. A strategy for

To determine whether the E3 ubiquitin ligases were capable of promoting Glis3 ubiquitina- tion as a result of their interaction, FLAG-Glis3 or the PY 461 mutant was co-expressed

We have demonstrated here that TRIM21 is tyrosine phosphorylated only in this domain indicating a possible role for the tyrosine phosphorylation of TRIM21 regulating its ability to

Recent- ly, GRAIL (the E3-ubiquitin ligase gene related to anergy in lymphocytes) was shown to be responsible for the Th2 hypore- sponsiveness in a mouse model of

An accumulation of SUMO chains also causes the extreme genome instability and cell cycle phenotypes of fission yeast that lack the SUMO-targeted E3 ubiquitin ligase (STUbL) Slx8-Rfp1

These genetic and biochemical results suggest that the Rtt101 Mms22 E3 ligase counteracts a function of Mrc1 that is linked to the replicative helicase at stalled replication forks,

Roc1b binds to the catalytic core of Cullin-3, and Klhl10 binds specifically to a unique testis-specific N- terminal Cullin-3 (TeNC) domain of Cul3 Testis that is required

Animals with loss of function mutations in either of two alleles (g48 and ye143) of the gene encoding the APC subunit EMB-27 APC6 showed increased chemotaxis towards diacetyl