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Drosophila melanogaster Hox transcription factors access the RNA polymerase II machinery through direct homeodomain binding to a conserved motif of mediator subunit Med19.

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Academic year: 2017

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Figure 2. Med19 mutations affect cell viability and Hox-related developmental processes
Figure 3. Synergistic interactions between Med19 and Hox mutations. Dose-sensitivity for Med19 was tested relative to Hox gain-of-function mutations of Antp (A–C), Dfd (D–F), and Ubx (G–I)

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