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Conserved Senescence Associated Genes and Pathways in Primary Human Fibroblasts Detected by RNA-Seq.

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Academic year: 2017

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Fig 1. Experimental design, growth curves and transition into senescence. (A) Experimental plan of culturing fibroblast cell strains derived from a single vial and maintained in culture as triplicates from an early PD until senescence at late PDs
Fig 2. Fifty most up-regulated genes with age in each of the five fibroblast strains. The red background represents genes commonly up-regulated with age in foreskin fibroblasts (HFF, BJ) and green background reveals genes commonly up-regulated among all th
Fig 3. Fifty most down-regulated genes with age in each of the five fibroblast strains
Fig 4. Significantly differentially regulated pathways with age across the five fibroblast strains
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