Influenza H5N1 and H1N1 virus replication and innate immune responses in bronchial epithelial cells are influenced by the state of differentiation.

Methods and Findings: The activity of DAS181 against several pandemic influenza A(H1N1) virus isolates was examined in MDCK cells, differentiated primary human respiratory

aeruginosa reduced VX-809, and VX809 + VX-770 stimulated Cl secretion in a CF cell line (CFBE cells) and in CF primary cultures of human bronchial epithelial (HBE) cells homozygous

Effect of cigarette smoke on the permeability and IL-1beta and sICAM-1 release from cultured human bronchial epithelial cells of never- smokers, smokers, and patients with chronic

aeruginosa, containing secreted virulence factors, induces ER stress in primary bronchial epithelial cells as evidenced by splicing of XBP1 mRNA and induction of CHOP, GRP78 and

The adaptive immune response to seasonal influenza viruses has been extensively characterized using a murine model of intranasal (I/N) infection with mouse-adapted influenza

Methods: Normal human primary breast epithelial cells and immortalized non-malignant mammary epithelial MCF-10A cells were grown in a three-dimensional overlay culture on

This endobronchial spread requires apical infection of differentiated human bronchial epithelial cells and apical release of infectious virus progeny as demonstrated for HAdV-B14p1

In the present study, we compared a influenza A(H1N1)pdm09 virus, a seasonal H3N2 strain and a prototypic H1N1 strain, and examined whether immunosuppression is involved in the