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Negligible immunogenicity of induced pluripotent stem cells derived from human skin fibroblasts.

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Academic year: 2017

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Fig. 1. Characterization of hiPSCs. (A) Expression of human ES cell-specific cell surface markers on hiPSCs were analyzed by flow cytometry
Fig. 3. Effect of IFN-c on hiPSCs. (A) Expression of MHC proteins and costimulatory molecules by hiPSCs treated with 100 ng/ml of IFN-c for 48h
Fig. 4. hiPSCs do not effectively induce activation and proliferation responses on allogeneic lymphocytes
Fig. 5. Cytokine expression profile in MLR. Culture supernatants were collected from the MLR after 24 hours of culture and examined for expression of cytokines secreted by Th1 (A), Th2 (B), and Th17 (C) (n57)
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