The responsibility for printing errors in the report and the paper texts lies with the authors of the reports. In addition, the management of resistant E.coli cells against mutagenic UV radiation at the given stage of the mutation process is largely due to the activity status of the uvr and rec F gene products and relatively less - rec A and lex A genes . Products. The modifying effect of kiwi extract in the final stages of mutagenesis is realized by the interaction between the two main ways to eliminate the induced primary damage to the DNA.
One of them is related to the state of the activity of the error-free DNA repair system, which is under the control of the constitutive enzyme of excision and post-replicate repair: products of uvr B (uvr AB-dependent exonuclease), rec F -gene (repairs but not recombination function of the unidentified product), rec BC gene (UV-induced endonuclease) and is always active in one of the two centers of the recA gene (protein RecA). It indicates that the related part of kiwi extract in two main processes of eliminating the primary damage of DNA determines the sufficiently high efficiency of modifications of induced mutagenesis in the last stages of mutation formation. Department of Botany, Plant Physiology and Genetics of Academic Sciences of the Republic of Tajikistan.
Planting improved material in small isolated houses or in the field (at altitudes above 2500 m above sea level).
Study of an initial selection material in a mountain zone and selection of healthy clones for ELISA tests (at altitude m . above sea level). Hybridization and reception of hybrids F1 of a potato in a mountain zone (at an altitude of 2500-2700 m above sea level).
Strains with the prion [PSI+] and with the normal conformation of Sup35 were investigated in the alpha-test. F3h-2 could acquire a new functional specialization in the common ancestor of the B, G and S genomes and in rye. THE INFLUENCE OF FUNCTIONING OF THE GENES FOR THE RECOGNITION AND REPAIR OF DNA DAMAGE ON LIFESPAN.
The frequency of the "illegitimate" hybridization is a criterion for the instability of the genome in the alpha test. Different phenotypes of hybrids in the alpha test correspond to different molecular events in the mating type switch. The effect of the late emergence of colonies of irradiated yeast cells was investigated in the dependence of radiation quality.
The aim of the study was to find hereditary mutations in the genes BRCA1, BRCA2, CHEK2, NBN, BLM1 in patients with inflammatory breast cancer.
RADIOBIOLOGY
Zingerone can potentially be used for selective protection of the normal tissue in connection with radiotherapy of tumor diseases. The aim of this work was to investigate the biological effect of IRL (850 nm, 101 Hz, 22 mW/cm2) on the induction of adaptive response in hemopoietic organs (bone marrow and thymus) and the rate of Ehrlich carcinoma growth on the offspring of mice (F1, F2 and F3). It was found that more pronounced negative changes of orientation and exploratory activity and of the levels of emotionality were observed in the groups after exposure to ionizing radiation and immobilization.
Of course, in the basis of the primary mechanism of action of radiohormesis doses is ionization of the atoms and molecules of the irradiated object, i.e. decrease in the size of the fraction SP is apparently due to the rapid transition of the SC into the progenitor cell pool. BYPASS EFFECTS, ADAPTIVE RESPONSE AND HORMESIS: BEING ON THE RIGHT PART OF THE STRESS RESPONSE CURVE.
However, the effect of additional stress factor ("cage") associated with the continuous chronic radiation exposure leads to insufficient production of erythropoiesis. Understanding the mechanisms that produce low-dose ionizing radiation-specific biological effects represents one of radiation biology's greatest challenges. Now we have knowledge not only of the main mechanisms of the radiation-induced effects (repair of DNA damage, detoxification of free radicals, cell cycle control and apoptosis), but also of certain regulatory processes of epigenetic response, which are based on the transposition activity of transposable (mobile ) elements (TEs).
In this regard, the identification of the biophysical mechanisms responsible for the observed cognitive impairments caused by radiation is one of the main questions in this field. Changes in the levels of the following compounds were assessed in the prefrontal cortex, hippocampus, striatum, nucleus accumbens and hypothalamus: noradrenaline (NA); The most significant differences in the character of age-related changes were observed in the prefrontal cortex, hypothalamus and nucleus accumbens.
Overall, the obtained results show that irradiation affects the dynamics of the temporal changes in the exchange of monoamines and their metabolites. 1218 individuals died in the cohort of offspring from the exposed fathers, 2223 - in the control group. MATHEMATICAL MODELING OF RADIATION-INDUCED DNA DOUBLE-STRAND BREAK REPAIR IN MAMMALIAN AND HUMAN CELLS.
STATISTICAL RECONSTRUCTION OF BACKGROUND RADIATION DOSES OF RURAL INHABITANTS OF THE URALS BASED ON EPR DOSIMETRY.
RADIOECOLOGY
Our results for the assessment of the distribution and redistribution of radionuclides in the agroecosystem showed a significant tendency of the formation of radiation exposure in humans. A comparative study of the seed progeny of dandelion (Taraxacum officiale) and plantain (Plantago major) was carried out with samples from cenopopulations grown for a long time under conditions of radioactive contamination (Eastern Ural radioactive trace area, EURT) or contamination chemical. (area of influence of the Nizhnii Tagil Metallurgical Plant, NTMP). Institute of Radiation Safety and Ecology of the National Nuclear Center of the Republic of Kazakhstan.
According to monitoring data, the artificial distribution of radionuclides in the central part of the lake has a stable character. LEGALITIES OF 90Sr AND 137Cs MIGRATION IN THE ECOSYSTEMS OF SEVASTOPOL BAY OF THE BLACK SEA. VERIFICATION OF THE 137Cs SOURCE USING PLUTONIUM ISOTOPIC ANALYSIS IN DEEP-WATER SEDIMENTS OF THE BLACK SEA.
Maximum concentrations of tritium in snow cover were found directly in streams of the STS (creeks at «Degelen» site and Shagan river) and they reach concentrations of tritium in surface water (40 kBq/kg). The main radioactive contamination of the vegetation cover of Semipalatinsk test site (STS) was formed as a result of surface (including excavation) nuclear tests, radioactive fallout (near and remote) and migration of radionuclides from surface and groundwater and testing of radioactive warfare agents ( WRA). The dose to the whole body exceeds the upper limit of the DCRL (1 mGy/day) at the most contaminated area.
Currently, the most polluted part of the EURT refers to the East-Ural State Reserve. CONCENTRATIONS OF RADIONUCLIDES IN ORGANISMS OF SOME SPECIES OF WILD ANIMALS LIVING IN THE TERRITORY OF THE. The territory of the test site varies both in landscape peculiarities and the nature of radioactive contamination.
They were taken at a distance of 50 and 100 m from the lake's shoreline. In the north-eastern part of the «Atomic» lake tritium prevails in organically bound form (81-85%), while in the opposite direction in the south-eastern part tritium prevails in the form of surface adsorbed water (38-41%) and tightly bound. form (34-45%). Brunch «Institute of Radiation Safety and Ecology» of RSE NNC RK, Kurchatov city, Kazakhstan.
The aim of the present work was therefore to calculate the internal doses in the tooth enamel.
EVOLUTION
The sex ratio was estimated in 117 specimens of three-spined stickleback (Gasterosteus aculeatus L., 1758) collected during the summer seasons in 2008–2014 in the coastal zone of different parts of the White Sea. These patterns are probably explained by stickleback migrations in the coastal area during spawning and post-spawning periods. This study was supported by the Program "Fundamentals of Biological Resource Management", the Program "Biodiversity of Natural Systems" (subprogramme . "Genepools of living nature and their conservation") and St.
In this paradigm, each pair in each genome can be described by one of two states: whether these genes are within the same operon or not. Such a consideration does not take into account the transitivity of the relation 'being in the same operon', and therefore conflicts may arise. Our approach considers operon as a collection of genes and is free from inconsistencies in the pairwise consideration.
We reconstruct the evolution of operon structure using Monte-Carlo minimization of the total number of events weighted by tree distances. Our approach was successfully tested on simulated data and then used for operon structure analysis of several metabolic systems in gammaproteobacteria. THE CENTRAL NERVOUS SYSTEM OF MAMMALS ACTS AS A MUTAGE/ANTI-MUTAGE FACTOR (POSSIBLE ROLE IN . MICROEVOLUTION) Daev E.V., Dukelskaya A.V.
The mutagenic/antimutagenic effects of mouse volatile pheromones serve as evidence that the central nervous system (CNS) of male house mice alters the level of genome instability in target cells of some peripheral organs. That will selectively affect the viability of the organisms and the genetic heterogeneity of their germ cells. World Congress of Landscape Ecology, IALE, Ottawa, Canada, 1991), we consider CNS as a time-saving factor for spatial genetic structure formation in house mouse populations with possible extension to other mammalian species.
One observation is that the emergence of young, aggressive pathogens (such as Yersinia pestis) is often accompanied by an increase in reassortment rates. The radioprotective effect of UvrDDr expression is also manifested in strains with recQ mutation in the major helicase of recombinational repair RecQ and with mutation in helicase IV encoding the helD gene.
