Animal models in research
Animal models in biological and biomedical research - experimental and ethical concerns
... an animal model. Chagas was in a small town in the countryside of minas Gerais (later named lassance, after the engineer ernesto lassance Cunha) working on a campaign against malaria during the ...
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Animal models of intellectual disability: towards a translational approach
... translational research called ‘‘bench-to-bedside and ...concerns research aimed at enhancing the adoption of best practices in the ...improvements in medical intervention for people with Down ...
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Experimental animal models of induced intraocular hypertension
... done in the same way as a figure or table by referring to the video or animation content and noting in the body text where it should be ...content. In order to ensure that your video or animation ...
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Animal models of anxiety: an ethological perspective
... strategy in preclinical anxiety research is not only indicated by the apparent limitations of existing animal mod- els, but also by the need for novel, safe and effective treatments for the full ...
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Experimental models in vaccine research: malaria and leishmaniasis
... Different animal models, especially mice and ham- sters, have been used and adapted to mimic human VL and to test vaccine ...candidates. In mice, chronic VL is successfully established after ...
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Animal models of alcohol and drug dependence
... reproduced in a laboratory setting without unavoidable ...modeled in laboratory animals. In this way, a wide range of techniques have been developed to model specific aspects of drug-taking ...
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Estimating the predictive validity of diabetic animal models in rosiglitazone studies
... Since models differ in physiological and genetic relevance, there is no single diabetic animal model which would fit for all scientific purposes; ideally, more than one species or strain are used ...
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Benefits of physical exercise on Parkinson’s disease disorders induced in animal models
... the research often is done in experimental models, especially ...PD in animal ...involving animal models and physical exercises, as well as other studies, which allowed an ...
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Tissue engineering in animal models for urinary diversion: a systematic review.
... tissue in urinary ...evaluated in (large) controlled and standardized animal ...constructs in animal models for urinary ...study, animal characteristics, study ...
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Animal models of obesity in rodents. An integrative review
... METHODS: Research was conducted in the CAPES Portal database using the following keywords “obesity animal models, diet and rodents”, published between the years 2010 to ...analyzed in ...
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Animal models in biological and biomedical research – experimental and ethical concerns
... Animal models have been used in experimental research to increase human knowledge and contribute to finding solutions to biological and biomedical ...of animal rights, has brought a ...
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Validating animal models for preclinical research: a scientific and ethical discussion
... 8. Regenberg, A., Mathews, D. J., Blass, D. M., Bok, H., Coyle, J. T., Duggan, P., Faden, R., Finkel, J., Gearhart, J. D., Hillis, A., Hoke, A., Johnson, R., Johnston, M., Kahn, J., Kerr, D., King, P., Kurtzberg, J., ...
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The role of animal models for research on severe malaria.
... role in pathology may have been ...experiments in this ...used in ECM, particularly when these were applied prior to the physiological signs of cerebral disease in mice, although the validity ...
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Pathogenesis of Epilepsy: Challenges in Animal Models
... Undoubtedly, animal models have provided useful information in addressing critical research issues, including mechanism of epileptogenesis, which are impossible to study in humans due ...
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Participatory Surveillance and Mathematical Models in Epidemiologic Research: Successes and Challenges
... living in malaria endemic regions typically carry Plasmod- ium falciparum parasites throughout life, clinical symptoms decrease markedly with age (Doolan et ...PfEMP1 in malaria pathogenesis has motivated ...
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Antiedematogenic activity of the indole derivative N-salicyloyltryptamine in animal models
... the in vitro LPS-induced release of the inflammation mediators TNF- α e ...2012). In turn, the release of IL-1 β by macrophages triggers inflammation and pain-related responses in different cell ...
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Models: an analysis of meanings in the literature on research in science education
... subject models contributes towards an innovative psychological reflection on human ...frequency in science education research studies, but with different ...model, in its distinct meanings, is ...
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Animal models of human atherosclerosis: current progress
... especially in the industrialized ...chronic in flammation act together leading to the formation and progression of atherosclerotic ...Adequate animal models are currently indispensable for ...
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Technologies for controlling ultrasound targeted drug delivery in brain using animal models
... parameter in the design of nasal drug delivery systems, as particles with a diameter greater than 10 μm remain in the nasal cavity and small particles in general tend to go all the way through the ...
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Erythrina mulungu in rats submitted to animal models of anxiety and depression
... data in the literature concerning the chemical constituents of ...observed in ETM one-way escape with EV and EM are due to their possibly different chemical ...components. In the FST, as expected, ...
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