down regulation
Down-regulation of myogenin can reverse terminal muscle cell differentiation.
... that down- regulation of endogenous myogenin gene expression in muscle cells can lead to reversal of muscle cell differentiation and the creation of mononucleated ...
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Histones Induce the Procoagulant Phenotype of Endothelial Cells through Tissue Factor Up-Regulation and Thrombomodulin Down-Regulation.
... The high circulating levels of histones found in various thrombotic diseases may compro- mise the anticoagulant barrier of endothelial cells. We determined how histones affect endo- thelial procoagulant tissue factor ...
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Down-regulation of 5-HT1B and 5-HT1D receptors inhibits proliferation, clonogenicity and invasion of human pancreatic cancer cells.
... receptors, using Western blot analysis. We investigated the expression of TCF8, as one of the EMT-inducing transcription factors belongs to ZEB1 family, which triggers epithelial dediffer- entiation by impairing the ...
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Correction: Inhibition of Nickel Nanoparticles-Induced Toxicity by Epigallocatechin-3-Gallate in JB6 Cells May Be through Down-Regulation of the MAPK Signaling Pathways.
... 1. Gu Y, Wang Y, Zhou Q, Bowman L, Mao G, Zou B, et al. (2016) Inhibition of Nickel Nanoparticles- Induced Toxicity by Epigallocatechin-3-Gallate in JB6 Cells May Be through Down-Regulation of the MAPK ...
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Berberine suppresses migration of MCF-7 breast cancer cells through down-regulation of chemokine receptors
... targeted down-regulation of CXCR4 expression in breast cancer cell line via different strategies like RNA interference (RNAi) or CXCR4 antagonists, significantly decreased metastasis of breast cancer cells ...
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HIV-1 infection causes a down-regulation of genes involved in ribosome biogenesis.
... a down-regulation of genes associated with the nucleolus, in particular those implicated in regulating the different steps of ribosome biogenesis, such as ribosomal RNA (rRNA) transcription, pre-rRNA ...
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pH-responsive artemisinin derivatives and lipid nanoparticle formulations inhibit growth of breast cancer cells in vitro and induce down-regulation of HER family members.
... Since survivin levels have been shown to be coupled to HER2 expression [47], we also observed that HER2 levels declined when BT474 cells were incubated with 100 nM–1 m M NP109 (Figure 3a). In addition, the level of ...
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Regulating Effect Of Carnosine And Or L- Arginine On The Expression Of Inflammatory Molecules Induced Nephropathy In The Hypoxic Rat Model
... in down regulation of the inflammatory molecule expression caused renal damage in response to sodium nitrite (NaNO2) induced hypoxia in rats ...markedly down regulated the serum pro-inflammatory ...
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Androgens and the male reproductive tract: an overview of classical roles and current perspectives
... concomitant down regulation of AR protein levels, that occur in both caput and cauda epididymis of adult rats submitted to bilateral surgical castration for 7- and 15-days, suggesting the existence of ...
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Cellular effects of everolimus and sirolimus on podocytes.
... a down-regulation of nephrin with increasing concentrations (0-100 nM) of EVL and SRL after 48 h of incubation, respectively (A, B); expression of nephrin in the simultaneous analysis (20 nM) was lower in ...
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Molecular candidates for early-stage flower-to-fruit transition in stenospermocarpic table grape (Vitis vinifera L.) inflorescences ascribed by differential transcriptome and metabolome profiles
... discerned regulation of auxin-, GA-, and ethylene-related genes during fruit set (Table 4) confirms the importance of plant hormones as mediators of the fruit developmental signal after pollination ...via ...
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Lipopolysaccharide induces a downregulation of adiponectin receptors in-vitro and in-vivo
... the down-regulation of adiponectin receptors in muscle, liver and fat de- pots in endotoxaemia may contribute to insulin resistance and hyperglycaemia frequently found in clinical conditions associated with ...
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Involvement of peroxidases in structural changes of barley stem
... peroxidase down-regulation ( Li et al. 2003) and that down-regulation of cationic peroxidase decreased lignin by 50% in tobacco ( Blee et ...
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Generation of a novel regulatory NK cell subset from peripheral blood CD34+ progenitors promoted by membrane-bound IL-15.
... the down-regulation of the immune response: reconverting mature myeloid DC (mDC) into immature/tolerogenic DC, blocking cytolytic functions on conventional NK cells and inducing HLA-G membrane expression on ...
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Stellungnahme zur Beurteilung der Äquivalenz von rekombinantem FSH und Menotropin
... Stimulation mit Down-Regulation im kurzen Protokoll Eine monozentrische Studie [34]. Keine Angaben zu Fall- zahlberechnung, statistischer Power, Art der Randomi- sierung, Drop-outs, Einverständniserklärung ...
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The gene expression profile of CD11c+ CD8α- dendritic cells in the pre-diabetic pancreas of the NOD mouse.
... the down-regulation in NOD pancreas CD8a – DCs of a network of important genes for beta cell regenerating growth factors, the REG ...The down-regulation of REG genes in the deficient NOD ...
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Resolvin D1 protects podocytes in adriamycin-induced nephropathy through modulation of 14-3-3β acetylation.
... To determine whether RvD1 can directly affect synaptopodin expression we investigated a mouse podocyte cell line. Preliminary studies found podocytes to be extremely sensitive to the toxic effects of Adriamycin. ...
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A new tumor suppressor that regulates tissue architecture.
... study, down-regulation of DEAR1 in normal mammary epithelial cells result- ed in formation of aberrant acinar struc- tures with decreased rates of apoptosis and a loss of normal cell ...polarity. ...
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Study of global transcriptional changes of N-GlcNAc2 proteins-producing T24 bladder carcinoma cells under glucose deprivation.
... We screened another key factor that linked up-regulation of UPR-related genes to the down-regulation of mitotic kinase genes. FOXO1, a transcription factor belonging to the androgen-mediated ...
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A DNMT3B alternatively spliced exon and encoded peptide are novel biomarkers of human pluripotent stem cells.
... faster down regulation of the DNMT3B exon 10 encoded peptide antigen relative to other protein biomarkers of pluripotent stem cells, we reexamined protein expression in mixed cultures of PSCs and SDCs using ...
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