HAM/TSP
Perfil dos biomarcadores plasmáticos de morbidade na mielopatia associada ao HTLV- 1/paraparesia espástica tropical (HAM/TSP)
... putative HAM/TSP (pHAM/TSP) and 28 ...that HAM/TSP presented a pro-inflammatory profile mediated by CXCL10/LTB-4/IL-6/TNF-α/IFN-γ, barely counterbalanced by the regulatory cytocines ...
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IL28B gene polymorphism SNP rs8099917 genotype GG is associated with HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP) in HTLV-1 carriers.
... The Ethical Board of the IIER approved the protocol (Number 13/ 2011), and an informed signed consent was obtained from all participants prior to study inclusion. The subjects were classified according to their ...
5
Avaliação do perfil de citocinas plasmaticas e da dosagem da carga proviral na mielopatia associada ao HTLVI: estudo comparativo entre portadores assintomáticos e pacientes com HAM/TSP
... with HAM/TSP followed up by the Interdisciplinary Group of Research on HTLV-1 ...few HAM/TSP symptoms (potential HAM/TSP); and 28(25, 9%) with ...with HAM/TSP and ...
75
Alterações neurocognitivas em pacientes com mielopatia associada ao HTLV-1/Paraparesia Espástica tropical: doença primária ou secundária a outros fatores associados?
... ao AMP-cíclico. Estas células, então, proliferam e produzem várias citocinas pró- inflamatórias e moléculas de adesão que poderiam favorecer a migração direcionada dos linfócitos T CD4+ infectados, da circulação para o ...
84
Dement. neuropsychol. vol.7 número4
... cal development favors the diagnosis of HAM/TSP with brain involvement over MS. Although the case shares symptoms with the primarily progressive form of MS, this diagnosis is unlikely. Both diseases show ...
5
Association of IL-10 Gene Polymorphisms and Human T Lymphotropic Virus Type I-Associated Myelopathy/tropical Spastic Paraparesis in North-East of Iran (Mashhad)
... same ethnic background and residing in the Khorasan province. They included 177 healthy controls, 80 random- ly selected HTLV-I carriers and 75 patients who fulfilled the accepted criteria for HAM/TSP (24). ...
6
Arq. NeuroPsiquiatr. vol.70 número4
... Phase 1 starts when the target cells inluenced by the HTLV-I tax protein promote expres- sion of the ligands on their surface, which starts production of pro-inlammatory cytokines such as IFN-gamma, TNF-alpha and IL-2, ...
2
Arq. NeuroPsiquiatr. vol.52 número4
... Clinical and demographic features of HTLV-1 associated myelopathy/ tropical spastic paraparesis (HAM/TSP) in Rio de Janeiro, Brazil.. Araújo AQ-C, Ali A, Newell A, Dalgleish AG and Rudg[r] ...
7
Arq. NeuroPsiquiatr. vol.73 número1
... HTLV-1 is the causal agent of HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP), a disease observed in up to 5% of individuals infected with HTLV-1. However, infected individuals without ...
1
Major Article Balance, functional mobility, and fall occurrence in patients with human T-cell lymphotropic virus type-1-associated myelopathytropical spastic paraparesis: a cross-sectional study
... evaluate body balance based on the execution of activities that require the maintenance of postural control. Each item is scored from 1 to 4, with the scale including a total of 54 points, and there is no previous cutoff ...
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Prevalence of anxiety, depression and quality of life in HTLV-1 infected patients
... The presence/absence of HAM/TSP is significantly associ- ated with high level depression (p < 0.001). Other signifi- cantly associated factors were: educational level (p < 0.001), family income (p = ...
5
Arq. NeuroPsiquiatr. vol.70 número4
... Objetivo: Comparar sintomas e sinais neurológicos em pacientes portadores do HTLV-1 assintomáticos e com síndrome de bexiga hiperativa (BH). Métodos: Foram estudados 102 indivíduos com HTLV-1 sem HAM/TSP ...
5
Arq. NeuroPsiquiatr. vol.53 número2
... SUMMARY - We analysed sera and cerebrospinal fluid (CSF) of 20 cases of human T-cell lymphotropic virus type (HTLV-I) associated myelopathy/tropical spastic paraparesis (HAM/TSP) from B[r] ...
5
Clinical and laboratory features of HTLV-I asymptomatic carriers and patients with HTLV-I-associated myelopathy tropical spastic paraparesis from the Brazilian Amazon
... Most HAM/TSP patients (9/11, 81,9%) were able to walk (OMDS ≤ 6) while 2 (18,1%) were wheel ...the HAM/TSP patients reported difficulty to walk, around half ...male HAM/TSP ...
9
Correlation between LTR point mutations and proviral load levels among Human T cell Lymphotropic Virus type 1 (HTLV-1) asymptomatic carriers
... leukemia; HAM/TSP: HTLV-I-associated myelopathy/tropical spastic paraparesis; CREB: Transcriptional activity of cAMP binding protein; NFkB: Nuclear factor kappa B; SRF: Serum Response Factor; AP-1: ...
7
Paraparesia espástica tropical/mielopatia associada ao HTLV-1: relato de dois casos com manifestações dermatológicas em familiares de doador de sangue HTLV-1 positivo assintomático no Hemocentro do Amazonas - Hemoam.
... Dois casos de paraparesia espástica tropical / mielopatia associada ao HTLV-1 (HAM/TSP) foram diagnosticados no Hemocentro do Amazonas – Hemoam, em familiares de doador de sangue soropositivo para o HTLV-1 ...
4
Short Communication The relationship between atopy and neurological manifestations in HTLV-1 infection
... non-atopic HAM/TSP ...non-atopic HAM/TSP patients was observed in this study, increased spontaneous IL-5 production was observed in atopic HAM/TSP patients when compared to non- ...
5
Expansion in CD39(+) CD4(+) Immunoregulatory T Cells and Rarity of Th17 Cells in HTLV-1 Infected Patients Is Associated with Neurological Complications
... in HAM/TSP patients as well as in other neuroinflamma- tory conditions with clinical similarities to HAM/TSP such as Multiple Sclerosis ...in HAM/TSP as in other inflammatory ...
15
Rev. Soc. Bras. Med. Trop. vol.48 número2
... nine HAM/TSP patients who were recruited from the Laboratory for Clinical and Epidemiological studies of Endemic Diseases of the Center for Tropical Medicine, Pará Federal University, Belém, Brazil ...
4
Mielopatia associada ao HTLV-1: análise clínico-epidemiológica em uma série de casos de 10 anos.
... com HAM/TSP, atendidos em um importante centro de referência público, para tratamento de mielopatias, comparar os resultados desse estudo com as demais publicações brasileiras, além de deinir quais ...
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