Mannose-binding lectin
Variant G57E of mannose binding lectin associated with protection against tuberculosis caused by Mycobacterium africanum but not by M. tuberculosis.
... Mannose-binding lectin (MBL) is a plasma opsonin of the collectin family. Its monomer consists of a 228-amino-acid polypeptide chain. Through extended alpha-helical structures it forms homotrimers ...
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Mannose-binding lectin inhibits monocyte proliferation through transforming growth factor-β1 and p38 signaling pathways.
... Mannose-binding lectin (MBL), a plasma C-type lectin, plays an important role in innate immunity. However, the interaction, and the consequences of it, between MBL and the immune system remain ...
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Association of levels of mannose-binding lectin and the MBL2 gene with type 2 diabetes and diabetic nephropathy.
... Objective: To investigate the association of Mannose-binding lectin ( MBL ) and the MBL2 gene with type 2 diabetes and diabetic nephropathy and the influence of MBL2 polymorphisms on ser[r] ...
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Mannose-binding lectin 2 (Mbl2) gene polymorphisms are related to protein plasma levels, but not to heart disease and infection by Chlamydia
... the mannose-binding lectin 2 (MBL2) gene was evaluated in a sample of 159 patients undergoing coronary artery bypass surgery (71 patients undergoing valve replacement surgery and 300 control ...
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Characterization of polymorphisms in the mannose-binding lectin gene promoter among human immunodeficiency virus 1 infected subjects
... Mannose-binding lectin (MBL) is a liver-derived, pluripotent serum lectin that plays a role in the human innate immune system, binding with high affinity to mannose or other ...
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INVESTIGAÇÃO DOS POLIMORFISMOS NO ÉXON 1 DO GENE MBL (MANNOSE-BINDING LECTIN) E SUA ASSOCIAÇÃO COM A SÍNDROME DA IMUNODEFICIÊNCIA ADQUIRIDA (AIDS)
... Mannose-binding lectin (MBL) and HIV. Activation of the C4 and C2 components of complement by a proteinase in serum bactericidal factor, Ra reactive factor. The C4 [r] ...
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High levels of serum mannose-binding lectin are associated with the severity of clinical signs of leptospirosis
... serum mannose-binding lectin (MBL) recognizes many pathogens, and low levels of this lectin are associated with susceptibility to ...this lectin in the pathogenesis of ...
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Genetically-defined deficiency of mannose-binding lectin is associated with protection after experimental stroke in mice and outcome in human stroke.
... Unlike the major contribution of MBL, the study did not unravel a significant involvement of MASP2 genotype or MASP-2 levels in the prognosis of stroke. It has been speculated that MASP- 2 deficiency might have broader ...
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Lack of association between mannose binding lectin and antibody responses after acellular pertussis vaccinations.
... of mannose to the vaccine. They found that when mannose was administrated together with the IBV vaccine, chickens with the low production of MBL produced Figure ...
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Role of mannose-binding lectin deficiency in HIV-1 and schistosoma infections in a rural adult population in Zimbabwe.
... Determination of plasma MBL concentration. Baseline plasma samples stored at -20°C were used for measurement of plasma MBL concentrations using the double enzyme immuno- assay (EIA) (Antibody Shop, Denmark) as described ...
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Association of mannose-binding lectin 2 gene polymorphisms with persistent Staphylococcus aureus bacteremia.
... C-type lectin that plays an important role in innate immunity as the front-line of the host defense system against microbial ...the lectin pathway of the complement system ...
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Rev. Soc. Bras. Med. Trop. vol.44 número1
... Introduction: he present study investigated the association between mannose-binding lectin (MBL) gene polymorphism and serum levels with infection by HIV-1. Methods: Blood samples (5mL) were ...
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Níveis séricos e polimorfismos gênicos da Lectina Ligadora de Manose (MBL) e da...
... BACKGROUND: Mannose-binding lectin (MBL) is a protein that recognizes carbohydrates on microbial surface leading to complement activation. This process is mediated by MBL-associated serine proteases, ...
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Níveis circulantes da lectina ligadora de manose (MBL) na degeneração macular relacionada à idade
... of mannose-binding lectin of the lectin complement pathway are associated with age-related macular ...serum mannose-binding lectin ...median mannose-binding ...
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Rev. Bras. Hematol. Hemoter. vol.36 número1
... 1. Holanda K, Lucena-Araujo AR, Quintas A, Mendonça T, Lima A, Vasconcelos LR, et al. Mannose-binding lectin 2 (MBL2) gene polymorphisms do not influence frequency of infection in chronic ...
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Rev. Soc. Bras. Med. Trop. vol.47 número3
... Mannose binding lectin (MBL) is a liver-derived pluripotent serum lectin and molecule of the innate response ...to mannose or other sugar components on the surface of viruses, bacteria, ...
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Distinct molecular strategies for Hox-mediated limb suppression in Drosophila: from cooperativity to dispensability/antagonism in TALE partnership.
... The emergence following gene duplication of a large repertoire of Hox paralogue proteins underlies the importance taken by Hox proteins in controlling animal body plans in development and evolution. Sequence divergence ...
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Different immunity elicited by recombinant H5N1 hemagglutinin proteins containing pauci-mannose, high-mannose, or complex type N-glycans.
... receptor binding to sialic acid. Greater sialic acid binding has been reported following the trimming and modification of the oligosaccharides of N-glycans such as single GlcNAc [17], pauci-mannose, ...
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The interaction between Histoplasma capsulatum cell wall carbohydrates and host components: relevance in the immunomodulatory role of histoplasmosis
... C-type lectin found in neu- trophils, natural killer cells, DC and a subset of T cells is important for the detection of glycosylated fungal com- ponents (Brown ...
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Mannan-Binding Lectin Is Involved in the Protection against Renal Ischemia/Reperfusion Injury by Dietary Restriction.
... Mannan Binding Lectin-A (MBL-A) and Mannan Bind- ing Lectin-C (MBL-C) were as follows: MBL-A (forward, 5'-CAG GGT CAC AAA CCT GTG AG 3'-; reverse, 5'-TGC AAC TTG TTG GTT AGC TG 3'-), MBL-C (forward, ...
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