NF-κB transcription factors
Targeting the NF-κB Pathway as a Combination Therapy for Advanced Thyroid Cancer.
... of NF-κB transcription factors shut- ting down canonical NF-κB ...estimating NF-κB transcription factor p65 binding to κB DNA consensus sites (TransAM ...
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Insect neuropeptide bursicon homodimers induce innate immune and stress genes during molting by activating the NF-κB transcription factor Relish.
... endocrine factors from the rest of the body) with recombinant bursicon (r-bursicon) heterodimer influenced the expression of 87 genes, most of which act during tanning and wing maturation ...
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IKKε knockout prevents high fat diet induced arterial atherosclerosis and NF-κB signaling in mice.
... of NF-kB dimers, the P65/P50 heterodimer is the most common form and plays the most important role in the activation of downstream targeted genes ...activate NF-kB ...activates transcription ...
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Enhancement of inflammatory protein expression and nuclear factor Κb (NF-Κb) activity by trichostatin A (TSA) in OP9 preadipocytes.
... of transcription factors including nuclear factor kB (NF-kB) and of mitogen-activated protein kinases (MAPKs) such as extracellular signal-regulated kinase (ERK), p38 MAPK and c-Jun N-terminal kinase ...
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Lack of effect of the Salmonella deubiquitinase SseL on the NF-κB pathway.
... of transcription factors, the NF-kB/Rel proteins, that regulate expression of genes involved in different biological processes such as cell proliferation, immune responses, inflammation and cell ...
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High-throughput analysis of NF-κB dynamics in single cells reveals basal nuclear localization of NF-κB and spontaneous activation of oscillations.
... a transcription factor that upon activation undergoes cycles of cytoplasmic-to-nuclear and nuclear-to-cytoplasmic transport, giving rise to so called ...on NF-kB dynamics in single ...analyzed NF-kB ...
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The velvet family of fungal regulators contains a DNA-binding domain structurally similar to NF-κB.
... fungus-specific transcription factors that directly bind to target DNA, even though analysis of their amino acid sequence does not reveal any known DNA-binding domains or ...mammalian transcription ...
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Hyperuricemia causes pancreatic β-cell death and dysfunction through NF-κB signaling pathway.
... glucose-responsive transcription factors PDX-1 and MafA amongst ...these transcription factors, we measured the expression of these proteins in mouse islets cultured with different ...
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Defining emerging roles for NF-κB in antivirus responses: revisiting the interferon-β enhanceosome paradigm.
... IRFs-3/7, NF-kB, and ATF- 2/c-Jun assemble on the ifnb enhancer, it was expected that all three factors would be critical for virus-triggered induction of ...key NF-kB subunits (such as RelA, c-Rel, ...
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Eukaryotic Initiation Factor 4H Is under Transcriptional Control of p65/NF-κB.
... NF-kB transcription factors play a major role as regulators of genes involved in cell proliferation, survival, and inflammatory response ...The NF-kB family includes RelA/p65, c-Rel, RelB, p50 ...
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Calcium/calcineurin synergizes with prostratin to promote NF-κB dependent activation of latent HIV.
... response. Transcription factors downstream of T-cell receptor activation, such as NF-kB/Rel and nuclear factor of activated T cells (NFAT) transcription members, are considered important ...
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hypoxia-inducible factors activate CD133 promoter through ETS family transcription factors.
... that mTOR signaling and HIF-1a are involved in regulating CD133 expression [28]. Although the reason for this is unclear, it is possible that HIFs are regulated by other mechanisms, such as ras-mitogen-activated protein ...
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MIRTFnet: analysis of miRNA regulated transcription factors.
... Transcription factors (TFs) are important factors regulating gene expression. Based on miRNA transfection experiments, methods have been suggested previously [in 22–25] detecting TFs that mediate at ...
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Effects of Cinnamon extract on biochemical enzymes, TNF-α and NF-κB gene expression levels in liver of broiler chickens inoculated with Escherichia coli
... Natural products, especially medicinal plants are increasin- gly used to cure various diseases such as infectious dise- ases, especially because of their multiplex properties and minimal adverse effects on the body. ...
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Plasma cytokine response, lipid peroxidation and NF- κ B activation in skeletal muscle following maximum progressive swimming
... supernatant was aliquoted and stored at -80°C. Protein was quantified using the Bradford assay reagent from Bio-Rad (USA). Nuclear extracts (20 µg) were separated by elec- trophoresis on a denaturing 10% ...
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Plasma cytokine response, lipid peroxidation and NF- κ B activation in skeletal muscle following maximum progressive swimming
... Our objective was to determine lipid peroxidation and nuclear factor-κB (NF-κB) activation in skeletal muscle and the plasma cytokine profile following maximum progressive swimming. Adult male Swiss ...
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NF-Y recruits both transcription activator and repressor to modulate tissue- and developmental stage-specific expression of human γ-globin gene.
... gene transcription indirectly by long-range interactions ...gene transcription both by binding to the LCR through an indirect, long-range mechanism and by directly binding to the proximal c- globin ...
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Quantification of cellular NEMO content and its impact on NF-κB activation by genotoxic stress.
... multiple NF-κB signaling pathways utilized reconstitution of NEMO mutants in NEMO-defi- cient ...inhibit NF- κ B signaling ...of NF-κB signaling by its stable reconstitution in ...
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Celastrol blocks interleukin-6 gene expression via downregulation of NF-κB in prostate carcinoma cells.
... aberrant NF-kB regulation existing in a myriad of cancers [32– 34]. The NF-kB protein family comprises RelA (p65), RelB, c-Rel, p50 (p105 precursor), and p52 (p100 precursor) ...state, NF-kBs are ...
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Roles of PPARγ/NF-κB signaling pathway in the pathogenesis of intrahepatic cholestasis of pregnancy.
... with NF-kB, causing inhibition of its signaling pathway or reducing the activated levels of NF-kB and subsequent inflamma- tion ...and NF-kB [33,34]. PPARc could inhibit activation of NF-kB ...
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