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Resistant Tuberculosis

Multidrug-resistant tuberculosis

Multidrug-resistant tuberculosis

... Despite the efforts made worldwide to reduce the number of cases of drug-susceptible tuber- culosis, multidrug-resistant tuberculosis (MDR-TB) constitutes an important public health issue. Around 440,000 ...

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The experience of surgical treatment of patients with pulmonary extensively resistant tuberculosis

The experience of surgical treatment of patients with pulmonary extensively resistant tuberculosis

... For the last time tendency for growing of drug resistant tuberculosis including extensively drug resistant TB is marked all over the world. In Kazakhstan nearly 48% of all cases among newly detected ...

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Extensively Drug-Resistant Tuberculosis: A Case Report and Literature Review

Extensively Drug-Resistant Tuberculosis: A Case Report and Literature Review

... drug-resistant tuberculosis (XDR-TB) is an emerging health problem that threatens tuberculosis (TB) control worldwide, since suitable treatment for this disease has not yet been ...pulmonary ...

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Resistance patterns, prevalence, and predictors of fluoroquinolones resistance in multidrug resistant tuberculosis patients

Resistance patterns, prevalence, and predictors of fluoroquinolones resistance in multidrug resistant tuberculosis patients

... Multidrug resistant tuberculosis (MDR-TB) defined as resis- tance to both isoniazid (H, INH) and rifampicin (R, Rif) is a major barrier to achieve successful TB ...drug resistant TB treatment ...

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Programmatic Management of Drug-Resistant Tuberculosis: An Updated Research Agenda.

Programmatic Management of Drug-Resistant Tuberculosis: An Updated Research Agenda.

... Drug-Resistant Tuberculosis Initiative includes: Heather Alexander, Amy Bloom, Sarabjit Chadha, Chen-Yuan Chiang, Daniela Cirillo, Charles Daley, Essam Elmoghazy, Jenni- fer Furin, Agnes Gebhard, Sirinapha ...

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Clinical and epidemiological profiles of individuals with drug-resistant tuberculosis

Clinical and epidemiological profiles of individuals with drug-resistant tuberculosis

... Drug-resistant tuberculosis (TB) is a growing global ...multidrug- resistant TB worldwide in 2012 and an estimated 170,000 people died from the ...Mycobacterium tuberculosis (MT) cultures and ...

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Multidrug-Resistant Tuberculosis: Case Reports Study in a Central State of Brazil

Multidrug-Resistant Tuberculosis: Case Reports Study in a Central State of Brazil

... Multidrug-resistant tuberculosis (MDR-TB) is an emerging and worrisome health problem that threatens tuberculosis (TB) control worldwide. The clinical management of MDR-TB is a complex issue ...

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Disease control implications of India's changing multi-drug resistant tuberculosis epidemic.

Disease control implications of India's changing multi-drug resistant tuberculosis epidemic.

... Background: Multi-drug resistant tuberculosis (MDR TB) is a major health challenge in India that is gaining increasing public attention, but the implications of India’s evolving MDR TB e[r] ...

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New and repurposed drugs to treat multidrug- and extensively drug-resistant tuberculosis

New and repurposed drugs to treat multidrug- and extensively drug-resistant tuberculosis

... multidrug-resistant tuberculosis (MDR-TB, resistant to at least isoniazid and rifampin) were reported in 2016, and that ...drug-resistant tuberculosis (XDR-TB) strains ...becoming ...

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Acquired and Transmitted Multidrug Resistant Tuberculosis: The Role of Social Determinants.

Acquired and Transmitted Multidrug Resistant Tuberculosis: The Role of Social Determinants.

... Although risk factors for multi-drug resistant tuberculosis are known, few studies have differ- entiated between acquired and transmitted resistance. It is important to identify factors associated with ...

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Epidemiology and Clinical Characteristics of Pediatric Drug-Resistant Tuberculosis in Chongqing, China.

Epidemiology and Clinical Characteristics of Pediatric Drug-Resistant Tuberculosis in Chongqing, China.

... drug resistant tuberculosis (DR-TB) in China that has the second largest burden of TB and the largest number of multidrug resis- tant (MDR) TB cases in the world, we performed the cross-sectional study to ...

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Multidrug-Resistant Tuberculosis in Patients with Chronic Obstructive Pulmonary Disease in China.

Multidrug-Resistant Tuberculosis in Patients with Chronic Obstructive Pulmonary Disease in China.

... multidrug-resistant tuberculosis (MDR-TB) is hampering efforts to control and manage the TB disease worldwide, since the effect of standard short course che- motherapy is less and second line drugs are less ...

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Combination of commercially available molecular assays and culture based methods in diagnosis of tuberculosis and drug resistant tuberculosis

Combination of commercially available molecular assays and culture based methods in diagnosis of tuberculosis and drug resistant tuberculosis

... our study, the overall PCR sensitivity was 70.4%, since only 72 (1.5%) specimens were smear-positive. The main advantage of PCR is speed, and, when combined with GenoType MTBDRplus assay directly in the PCR-positive ...

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Randomized trials to optimize treatment of multidrug-resistant tuberculosis.

Randomized trials to optimize treatment of multidrug-resistant tuberculosis.

... Competing Interests: The authors have declared that no competing interests exist. The findings and conclusions in this report are those of the authors and do not necessarily represent the views of the United States ...

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Sequential analysis as a tool for detection of amikacin ototoxicity in the treatment of multidrug-resistant tuberculosis

Sequential analysis as a tool for detection of amikacin ototoxicity in the treatment of multidrug-resistant tuberculosis

... the incidence rate ranges from 11.0 to 68.4/100,000 population among the states, with the lowest and highest rates being observed in the states of Goiás and Amazonas, respectively. Rio de Janeiro has an incidence rate of ...

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Multi drug resistant tuberculosis in Mosango, a rural area in the Democratic Republic of Congo.

Multi drug resistant tuberculosis in Mosango, a rural area in the Democratic Republic of Congo.

... Multidrug Resistant Tuberculosis (MDR-TB) is a serious threat which jeopardizes the worldwide efforts to control TB. The Democratic Republic of Congo (DRC) is one of 27 countries with a high burden of ...

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Drug-resistant tuberculosis among HIV-infected patients starting antiretroviral therapy in Durban, South Africa.

Drug-resistant tuberculosis among HIV-infected patients starting antiretroviral therapy in Durban, South Africa.

... Mycobacterium tuberculosis culture (Middlebrook 7H11 solid agar medium and BACTEC mycobacterial growth indicator tube [MGIT] 960 System; ...drug resistant strain (A169) were included with each batch of ...

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Nitrate reductase assay using sodium nitrate for rapid detection of multidrug resistant tuberculosis

Nitrate reductase assay using sodium nitrate for rapid detection of multidrug resistant tuberculosis

... One-hundred and six M. tuberculosis strains belonging to the collection of the Institute of Tropical Medicine of Antwerp, Belgium, were studied. The strains were cultured in LJ medium and incubated at 37°C for ...

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Predictors of multidrug- and extensively drug-resistant tuberculosis in a high HIV prevalence community.

Predictors of multidrug- and extensively drug-resistant tuberculosis in a high HIV prevalence community.

... Our study also identified hospitalization as an important risk factor for MDR and XDR tuberculosis, with prolonged hospital- ization associated with a 3- to 6-fold increase in risk, respectively. This finding ...

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Use of a molecular diagnostic test in AFB smear positive tuberculosis suspects greatly reduces time to detection of multidrug resistant tuberculosis.

Use of a molecular diagnostic test in AFB smear positive tuberculosis suspects greatly reduces time to detection of multidrug resistant tuberculosis.

... Limitations of the MTBDRplus assay include detection of resistance to only RIF and INH, and the need for high-level technical skill and infrastructure usually relegating its use to a referral or regional laboratory. ...

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