Serine-proteases
Characterization of cDNAs encoding serine proteases and their transcriptional responses to Cry1Ab protoxin in the gut of Ostrinia nubilalis larvae.
... group CTP-G1. One chymotrypsin gene (SlCTLP) from S. litura (accession No. GQ354838) was food-inducible and was suppressed by starvation [26]. Therefore, the OnCTPs from CTP-G1 may play a similar role in protein ...
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CHANGES IN LEVELS OF ACTIVITY OF SERINE PROTEASES ACCOMPANY THE EXPOSURE OF COMMON BEAN (PHASEOLUS VULGARIS L.) TO WATER DEFICIT
... Cysteine proteases have frequently been reported to be influenced by drought, but only a few serine proteases (SP), among them the trypsin-like enzyme and two aminopeptidases from bean leaves ...
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Scabies mite inactive serine proteases are potent inhibitors of the human complement lectin pathway.
... inactive serine protease paralogues (SMIPP-Ss) thought to be implicated in host defence ...MBL-associated serine proteases (MASPs) and released the MASP-2 enzyme from the ...
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Distinct spatiotemporal expression of serine proteases Prss23 and Prss35 in periimplantation mouse uterus and dispensable function of Prss35 in fertility.
... PRSS23 and PRSS35 are homologous proteases originally identified in mouse ovaries. In the periimplantation mouse uterus, Prss23 was highly expressed in the preimplantation gestation day 3.5 (D3.5) uterine luminal ...
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Cleavage specificity analysis of six type II transmembrane serine proteases (TTSPs) using PICS with proteome-derived peptide libraries.
... By knowing the cleavage site and preferred amino acids in recognition sequences, more specific and selective inhibitors can be developed. To overcome these challenges, we used a proteomics approach to determine the ...
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Trypsin-like serine proteases in Lutzomyia longipalpis--expression, activity and possible modulation by Leishmania infantum chagasi.
... Methodology and Principal Findings: In order to study trypsin expression profiles we produced antibodies against peptides specific for Lltryp1 and Lltryp2. The anti-Lltryp1-peptide antibody revealed a band of 28 kDa ...
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Functional analysis of a missense mutation in the serine protease inhibitor SPINT2 associated with congenital sodium diarrhea.
... intestinal serine proteases tested in our ...other serine protease of Kunitz type ...membrane-bound serine prote- ases are probably complex and not limited to the interaction between one ...
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Biochemical and molecular characterization of a serine keratinase from Brevibacillus brevis US575 with promising keratin-biodegradation and hide-dehairing activities.
... The classification analysis of the deduced amino acid sequence demonstrated that the mature keratinase was a member of the serine protease family. The alignment of the deduced amino acid sequence of kerUS with ...
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Purificação e caracterização parciais de serino e cisteíno proteases de Sitophilus zeamais (Coleoptera: Curculionidae)
... cysteine proteases of a susceptible and two resistant strain (one with a cost associated with resistance and other without cost) of the maize weevil Sitophilus zeamais were partially purified using an affinity ...
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Biochemical Aspects of a Serine Protease from Caesalpinia echinata Lam. (Brazilwood) Seeds: A Potential Tool to Access the Mobilization of Seed Storage Proteins
... other serine proteases purified from legumi- nous seeds, ...of serine proteases (aprotinin, SBTI, and CeKI), nor by PMSF (Table ...several serine proteases in animal physiolo- ...
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Bowman-Birk protease inhibitor from Vigna unguiculata seeds enhances the action of bradykinin-related peptides
... infusions. These results indicate that the BTCI-Bk-related peptides complexes may be a good strategy to act as a carrier and protective approach for the cleavage of serine proteases, leading to an increase ...
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Mauro Manuel Martinez-Pacheco1 , Alberto Flores-Garcia
... of serine protease was detected as well as aspartyl protease there was a slight increase in metalloprotease ...that serine proteases are involved in heat shock and oxidative stress (ITZHAKI et ...
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Purificação e caracterização de proteases do veneno da Pseudechis australis e de...
... as proteases separadas são renaturadas dentro do gel, por lavagens repetidas com um detergente não-iónico, como o Triton X-100, que substitui o SDS do ...as proteases renaturadas realizem a digestão do ...
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Respostas bioquímica, fisiológica e comportamental de Anticarsia gemmatalis (lagarta da soja) ao inibidor de serino proteases benzamidina
... de proteases produzidos pelas plantas não é ...de proteases, o inseto produz proteases de classes diferentes que poderão degradar inclusive o inibidor protéico produzido por esta planta e desta forma ...
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Purificação Preparativa de Inibidores Bowman-Birk, Quantificação em Alimentos e Características Imunogênicas dos Inibidores da Glycine max e da Macrotyloma axillare
... as proteases tripsina-símile envolvidas na carcinogênese devem ser consideradas alvos potenciais de proteínas relacionadas ao BBI (Clementea and Domoney, ...
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Aplicação farmacêutica de inibidores de proteases : uma prospecção tecnológica
... as proteases realizam uma gama de funções ...de proteases decorrem da evolução de inúmeros suportes estruturais (LI et ...686 proteases e seus homólogos são definidas no genoma humano, a maioria dos ...
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Biomarcadores cardíacos em cães com degeneração mixomatosa da valva mitral submetidos a um programa de condicionamento físico
... biomarcadores, bem como a utilização de tubos desprovidos de inibidores de proteases, condições que podem ter interferido com os métodos analíticos empregados. Como o [r] ...
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Efeito antimetastático e mecanismos de ação de proteases do látex de Vasconcellea cundinamarcensis (Carica candamarcensis)
... as proteases contidas em CMS-2 são as responsáveis pela ação antimetastática de P1G10 e contribui para esse efeito a citotoxicidade, por apoptose e dependente de suas atividades proteolíticas e, ainda, a redução ...
4
Design, síntese e avaliação biológica de inibidores de proteases de cisteína
... as proteases de serina, são a classe de proteases mais abundante, tendo uma distribuição muito vasta - estão descritas em animais, plantas, bactérias e vírus – o que torna o campo de aplicação para ...
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Targeting exosites on blood coagulation proteases
... coagulation proteases has been attributed not only to residues surrounding the active site but also to other surface domains that are involved in recognizing and interacting with macromolec- ular substrates and ...
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