[PDF] Top 20 Association of single nucleotide polymorphisms in TCF2 with type 2 diabetes susceptibility in a Han Chinese population.

... analysis of anatomical, archeological, linguistic and genetic data have consistently suggested the presence of a significant boundary between northern and southern populations in China, with ... See full document

... Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 ... See full document

... lack of the expression of estrogen receptor (ER), progesterone receptor (PR) and human epidermal growth factor receptor 2 ...lack of targeted therapies. MicroRNA (miRNA) as a novel modulator ... See full document

... risk of SLE, whereas GGTG was associated with susceptibility to ...presented in Table 2 and Table 3, it is possible that the haplotype GGCG, which provides protection to SLE, results ... See full document

... method with one of the primers containing a nucleotide mismatch, which enables the use of restriction enzymes for discriminating sequence variations ...aliquots of PCR- amplified ... See full document

... heterogeneity of rs7903146 resulted from the studies by Chang [18], Ng [29], and Wen [32], while the heterogeneity of rs12255372 was attributed to the study by Fan ...populations of the involved ... See full document

... 25 single nucleotide polymorphisms (SNPs) from 24 genetic loci which were identified as being associated with BMI, body weight, WC, or obesity status by previous GWAS ...SNPs with ... See full document

... consisted of 565 female patients with sporadic breast cancer and 605 age- and sex-matched healthy ...controls. In total, 12 single nucleotide polymorphisms (SNPs) in the ... See full document

... role in UC development [10,26]. In this regard, recent studies have suggested that Th17 cells mediated intestinal inflammation ...production of IL-17 and to be required for Th17 differentiation ... See full document

... involved in the body energy ...the association of single nucleotide polymorphisms (SNPs) of the preproghrelin gene with type 2 diabetes, ... See full document

... Statistical analyses were performed using SPSS 13.0 software for Windows (SPSS Inc., Chicago, IL). Continuous variables were expressed as mean and standard deviation or median and interquartile range (25%–75%), according ... See full document

... none of these hypotheses has fully accounted for the diversity of the initial events that result in the deposition of senile plaques and neurofibrillary ...number of studies point out ... See full document

... consideration in addressing the significant genetic association is population stratification inherent to case control study, which however, could be minimized in the current research, as ... See full document

... cause of cancer deaths worldwide [1]. The severity of HCC and the lack of effective treatment strategies make the disease a major ...associated with several risk factors, including chronic ... See full document

... role in the immune system and local inflammatory response. LTA is expressed in atherosclerotic plaques and has been implicated in the pathogenesis of atherosclerosis and coronary heart disease ... See full document

... the association of loci on chromosome 8p with ...located in chromosome 8p21.3 was also found to be involved in the etiology of ...role of EGR3 in Chinese ... See full document

... development of AS is associated with complex interactions between environmental factors and immune responses ...progression of AS. IL23 is one of the master regulators of ...production ... See full document

... pathogenesis of MI is the rupture of coronary atherosclerotic ...roles of SIRT1 in inflammation processes, vascular endothelial homeostasis and ath- erosclerosis [20,35,36], providing evidence ... See full document

... The population history of Northern Europe has been reviewed earlier by several authors ...settlement of the Baltic Sea region advanced rapidly after the Ice Age, beginning about 14,000 BC in ... See full document

... prediction of the transcription factor binding CYP2D6 promoter region provided the foundation for investigating the molecular mechanism of the phenotype profile of ...involved in both Haplo3 ... See full document