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[PDF] Top 20 Features in HIV genotypes associated with failure in the computational prediction of patients' response to antiretroviral treatment

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Features in HIV genotypes associated with failure in the computational prediction of patients' response to antiretroviral treatment

Features in HIV genotypes associated with failure in the computational prediction of patients' response to antiretroviral treatment

... attacking the immune system and gradually destroying the TCD4+ defense ...adequate treatment, the carriers develop the most severe form of the infection, AIDS, when ... See full document

11

Predictors of immunological failure of antiretroviral therapy among HIV infected patients in Ethiopia: a matched case-control study.

Predictors of immunological failure of antiretroviral therapy among HIV infected patients in Ethiopia: a matched case-control study.

... shown to have a significant influence on probability of immunological treatment failure in the univariate analysis and multivariate ...analysis. In fact, most literatures ... See full document

13

HIV-1 Genotypes Related to Failure of Nelfinavir as the First Protease Inhibitor Treatment

HIV-1 Genotypes Related to Failure of Nelfinavir as the First Protease Inhibitor Treatment

... Combined antiretroviral therapy results in sustained viral suppression and a decrease in mortality and morbidity due to HIV ...absence of cross- resistance are key factors ... See full document

6

Factors associated with mortality in HIV patients failing antiretroviral therapy, in Salvador, Brazil

Factors associated with mortality in HIV patients failing antiretroviral therapy, in Salvador, Brazil

... time with HAART have resulted in decreased virologic failure ...use of HAART may select viral strains with mutations that allow the maintenance of HIV ... See full document

4

Adherence to antiretroviral treatment in HIV-1 infected subjects : prevalence and associated factors

Adherence to antiretroviral treatment in HIV-1 infected subjects : prevalence and associated factors

... self-reports of adherence is one the most commonly used measure in both clinical and research settings, due to its low burden, being inexpensive and, in clinical setting, allowing ... See full document

197

Response to treatment with interferon-alpha and ribavirin in patients with chronic Hepatitis C virus genotypes 2 and 3 depends on the degree of hepatic fibrosis

Response to treatment with interferon-alpha and ribavirin in patients with chronic Hepatitis C virus genotypes 2 and 3 depends on the degree of hepatic fibrosis

... adult patients with chronic hepatitis C virus, with detectable HCV-RNA in the peripheral blood detected by PCR, who received a combined therapy of INF-α+RBV, which was provided ... See full document

4

STUDY OF ANTIRETROVIRAL MUTANTS IN HIV PATIENTS WITH TREATMENT FAILURES AND THE EFFECT OF RISK FACTORS IN THE VIROLOGICAL FAILURES

STUDY OF ANTIRETROVIRAL MUTANTS IN HIV PATIENTS WITH TREATMENT FAILURES AND THE EFFECT OF RISK FACTORS IN THE VIROLOGICAL FAILURES

... Discussion: The most important factor related to treatment response in this study was adherence to ...Mutations in RT were related to the treatment ... See full document

5

HIV-1 Proviral DNA Loads (as Determined by Quantitative PCR) in Patients Subjected to Structured Treatment Interruption after Antiretroviral Therapy Failure

HIV-1 Proviral DNA Loads (as Determined by Quantitative PCR) in Patients Subjected to Structured Treatment Interruption after Antiretroviral Therapy Failure

... presence of proviral DNA associated with the generation of replication-competent viruses in various cellular compartments has been a major barrier to virologic control ... See full document

2

The individualized genetic barrier predicts treatment response in a large cohort of HIV-1 infected patients.

The individualized genetic barrier predicts treatment response in a large cohort of HIV-1 infected patients.

... success of combination antiretroviral therapy is limited by the evolutionary escape dynamics of ...class of probabilistic graphical models, to describe this ...rise to a ... See full document

11

Cost-effectiveness of genotypic antiretroviral resistance testing in HIV-infected patients with treatment failure.

Cost-effectiveness of genotypic antiretroviral resistance testing in HIV-infected patients with treatment failure.

... model to approximate the real-world and project long-term costs and outcomes of ...one of the largest cohort studies on HIV disease to reflect a real-world setting ... See full document

8

Adherence to antiretroviral treatment for hiv and inter-its relationship with the programmatic vulnerability

Adherence to antiretroviral treatment for hiv and inter-its relationship with the programmatic vulnerability

... participation in the management of services (A14) contributes to the development of public policies and the establishment of strategies that will meet the ... See full document

12

Methodological features of the physical rehabilitation in the surgical treatment of vertebral pathology for patients with kyphosis

Methodological features of the physical rehabilitation in the surgical treatment of vertebral pathology for patients with kyphosis

... Methodological features of the physical rehabilitation in the surgical treatment of vertebral pathology for patients with ...kyphosis. The associate ... See full document

4

Metabolic Effects Associated to the Highly Active Antiretroviral Therapy (HAART) in AIDS Patients

Metabolic Effects Associated to the Highly Active Antiretroviral Therapy (HAART) in AIDS Patients

... proposed to explain the development of dyslipidaemia in HIV-infected patients, involving several proposed interactions between the virus, antiretroviral therapies, ... See full document

7

Factors associated with adherence to antiretroviral therapy in HIVAIDS patients: a cross-sectional study in Southern Brazil

Factors associated with adherence to antiretroviral therapy in HIVAIDS patients: a cross-sectional study in Southern Brazil

... on HIV-infected adults being treated with antiretroviral drugs at a reference service in Southern ...Adherence to treatment was assessed by a self-report inventory developed for ... See full document

9

Putative IL-10 Low Producer Genotypes Are Associated with a Favourable Etanercept Response in Patients with Rheumatoid Arthritis.

Putative IL-10 Low Producer Genotypes Are Associated with a Favourable Etanercept Response in Patients with Rheumatoid Arthritis.

... variability in IL-10 secretion is determined to a large scale by genetic vari- ance ...[13]. The IL-10 promoter contains polymorphic elements that combine to form 4 major haplotype families ... See full document

13

KIR-HLA genotypes in HIV-infected patients lacking immunological recovery despite effective antiretroviral therapy.

KIR-HLA genotypes in HIV-infected patients lacking immunological recovery despite effective antiretroviral therapy.

... at the same locus: both are inhibitory KIRs, but KIR2DL3 has a weaker inhibitory potential ...result in greater activation of NK cells and, consequently, in more efficient control of ... See full document

7

Response to treatment in Brazilian patients with chronic hepatitis C is associated with a single-nucleotide polymorphism near the interleukin-28B gene

Response to treatment in Brazilian patients with chronic hepatitis C is associated with a single-nucleotide polymorphism near the interleukin-28B gene

... that the IL28B poly- morphism is a good predictor of SVR, independent of other factors, such as age, gender, stage of liver fibrosis and ...Due to the admixture of ... See full document

6

Prevalence of antiretroviral drug resistance among treatment-naive and treated HIV-infected patients in Venezuela

Prevalence of antiretroviral drug resistance among treatment-naive and treated HIV-infected patients in Venezuela

... estimated to be infect- ed with human immunodeficiency virus type 1 (HIV-1) in Latin America, including some 110,000 in Venezuela (UNAIDS/WHO ...2007). The most frequently ... See full document

4

Profile of use of antiretroviral drugs by patients with HIV treated in Aracaju – SE, Brazil

Profile of use of antiretroviral drugs by patients with HIV treated in Aracaju – SE, Brazil

... A síndrome da imunodeficiência adquirida (AIDS) é um grave problema de saúde pública e enfrenta problemas relacionados a falta de adesão ao tratamento. O objetivo do estudo foi identificar o perfil da adesão à ... See full document

11

HIV reservoirs and immune surveillance evasion cause the failure of structured treatment interruptions: a computational study.

HIV reservoirs and immune surveillance evasion cause the failure of structured treatment interruptions: a computational study.

... obtained in a previous work [32] on a shorter therapeutic period (6 months) and optimized by using a genetic algorithm indicated an optimized therapy with a week-on week-off pattern after a period of ... See full document

10

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