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[PDF] Top 20 Genetic association of the KLK4 locus with risk of prostate cancer.

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Genetic association of the KLK4 locus with risk of prostate cancer.

Genetic association of the KLK4 locus with risk of prostate cancer.

... histopathologically-confirmed prostate cancer cases were recruited through private and public urologists in Queensland, Australia via three prostate cancer studies or resources: the ... See full document

14

Imputation of the rare HOXB13 G84E mutation and cancer risk in a large population-based cohort.

Imputation of the rare HOXB13 G84E mutation and cancer risk in a large population-based cohort.

... evidence of the association of the HOXB13 G84E mutation with prostate cancer, and provided age-specific risks for developing prostate cancer for ... See full document

19

Association of Polymorphism rs198977 in Human Kallikrein-2 Gene (KLK2) with Susceptibility of Prostate Cancer: A Meta-Analysis.

Association of Polymorphism rs198977 in Human Kallikrein-2 Gene (KLK2) with Susceptibility of Prostate Cancer: A Meta-Analysis.

... for prostate carcinogenesis [16]. All of these observations strongly implicate KLK2 as a plausible candidate gene involved in PCa ...number of studies have assessed the association ... See full document

6

Assessment of possible association between rs378854 and prostate cancer risk in the Serbian population

Assessment of possible association between rs378854 and prostate cancer risk in the Serbian population

... UK Genetic Prostate Cancer Study Collaborators; British Association of Urological Surgeons’ Section of Oncology; UK ProtecT Study Collaborators, Horwich, ...associated ... See full document

12

Joint effects of febrile acute infection and an interferon-γ polymorphism on breast cancer risk.

Joint effects of febrile acute infection and an interferon-γ polymorphism on breast cancer risk.

... cascade of host defense mechanisms by inducing the proliferation and differentiation of leucocytes and the secretion of interferons (IFNs), tumor necrosis factor (TNF)-a, antibodies, ... See full document

7

Performance of an adipokine pathway-based multilocus genetic risk score for prostate cancer risk prediction.

Performance of an adipokine pathway-based multilocus genetic risk score for prostate cancer risk prediction.

... cohort of men subjected to prostate biopsy due to abnormal clinical and/or PSA findings where an extensive biopsy scheme was used, we showed that by adding a genetic score based on 7 SNPs ... See full document

9

Functional analysis of genetic variants associated  with risk for breast cancer: 12q24, a candidate risk locus

Functional analysis of genetic variants associated with risk for breast cancer: 12q24, a candidate risk locus

... altering the binding affinity of transcription ...evidence of cis-regulatory variants acting in different ways, for example, altering miRNA ...in the 3’UTR of mRNA sequence), affecting ... See full document

96

Genetic polymorphisms of the glycine N-methyltransferase and prostate cancer risk in the health professionals follow-up study.

Genetic polymorphisms of the glycine N-methyltransferase and prostate cancer risk in the health professionals follow-up study.

... in the promoter region that may affect transcriptional activity: short tandem repeat 1 (STRP1), a (GA)n dinucleotide repeat polymor- phism, INS/DEL with insertion or deletion of a GAGT ... See full document

7

The impact of metformin use on the risk of prostate cancer after prostate biopsy in patients with high grade intraepithelial neoplasia

The impact of metformin use on the risk of prostate cancer after prostate biopsy in patients with high grade intraepithelial neoplasia

... lop cancer than those without HGPIN (36.3% vs. 25%) (17). The clinical importance of recognizing HGPIN is based on its strong association with PCa, so its identification in biopsy ... See full document

6

Re: Lack of association between Matrix Metalloproteinase-1 (MMP-1) promoter polymorphism and risk of renal cell carcinoma

Re: Lack of association between Matrix Metalloproteinase-1 (MMP-1) promoter polymorphism and risk of renal cell carcinoma

... The genetic population based studies are mainly aimed at identifying groups at a higher risk of developing a cancer or at a higher risk of having a cancer ... See full document

2

Genetic variants in the MicroRNA biosynthetic pathway Gemin3 and Gemin4 are associated with a risk of cancer: a meta-analysis

Genetic variants in the MicroRNA biosynthetic pathway Gemin3 and Gemin4 are associated with a risk of cancer: a meta-analysis

... evaluated the relationship between polymorphisms in Gemin3 or Gemin4 and cancer ...articles, with a pooled total of 2,588 cases and 2,549 controls, relevant to the relationship between ... See full document

14

Lack of association of interferon regulatory factor 1 with severe malaria in affected child-parental trio studies across three African populations.

Lack of association of interferon regulatory factor 1 with severe malaria in affected child-parental trio studies across three African populations.

... member of the IRF family of transcription factors, which have key and diverse roles in the gene-regulatory networks of the immune ...mediator of IFN-gamma signalling and ... See full document

7

Lack of detection of human papillomavirus DNA in prostate carcinomas in patients from northeastern Brazil

Lack of detection of human papillomavirus DNA in prostate carcinomas in patients from northeastern Brazil

... associated with either BPH or prostate ...no association between the persistence of HPV infection and the risk of developing prostate cancer, ... See full document

6

Effects of interleukin-10 polymorphisms, Helicobacter pylori infection, and smoking on the risk of noncardia gastric cancer.

Effects of interleukin-10 polymorphisms, Helicobacter pylori infection, and smoking on the risk of noncardia gastric cancer.

... Effects of H. pylori Infection and Smoking on the Association between IL10 Genetic Variants and the Risk of Advanced Atrophy and Intestinal Metaplasia in the Antrum ... See full document

8

Genetic polymorphisms of GSTM1, GSTT1, and GSTP1 with prostate cancer risk: a meta-analysis of 57 studies.

Genetic polymorphisms of GSTM1, GSTT1, and GSTP1 with prostate cancer risk: a meta-analysis of 57 studies.

... type of study and ...studies. The inclusion criteria were: (1) studies which evaluated associations between GSTM1, GSTT1, GSTP1 polymorphisms and PCa risk; (2) control population did not contain ... See full document

12

Ethnic background and genetic variation in the evaluation of cancer risk: a systematic review.

Ethnic background and genetic variation in the evaluation of cancer risk: a systematic review.

... Though the most of the associations between genetic variants and cancer risk that were assessed in this study do not replicate between ethnic groups, this does not establish that ... See full document

11

Strong signature of natural selection within an FHIT intron implicated in prostate cancer risk.

Strong signature of natural selection within an FHIT intron implicated in prostate cancer risk.

... forces of mutation, natural selection, genetic drift, and recombination have shaped the pattern of variation in the human ...important genetic variations that result in ... See full document

8

The Influence of Small Amounts of Aluminium on the Spheroidization of Cast Iron with Cerium Mischmetal

The Influence of Small Amounts of Aluminium on the Spheroidization of Cast Iron with Cerium Mischmetal

... determine the influence of aluminium in the amount from about ...on the structure of cast iron treated with cerium mischmetal and subjected to graphitizing modification ... See full document

6

Prostate Cancer: A State of The Heart

Prostate Cancer: A State of The Heart

... as the back door pathway, allows them to proliferate by binding to the androgen response element in the genome to trigger various signal transduction pathways; indings that have changed the ... See full document

6

The modification process of AlSi21CuNi silumin and its effect on change of mechanical properties of the alloy

The modification process of AlSi21CuNi silumin and its effect on change of mechanical properties of the alloy

... modifiers of hypereutectic ...case the aluminum phosphide, AlP, becomes the nucleus of the ...In the studies [11-12] is presented a new view on interaction of phosphorus ... See full document

4

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