[PDF] Top 20 The role of ischemic preconditioning in the expression of apoptosis-related genes in a rat model of intestinal ischemia-reperfusion injury

... used the Rat Endothelial Cell Biology RT² Profiler PCR Array, which evaluate the expression of 84 genes related to endothelial cell ...84 genes, 28 are directly ... See full document

... mechanisms of tissue responses to ischemic stress and factors inducing ...into the molecular pathophysiol- ogy of human ...transfer of vascular endothelial growth factor (VEGF), ... See full document

... to the quality of a kidney graft, which has a direct association with the survival of the ...for the success of a kidney graft is the warm ischemic time ... See full document

... sue injury following ischemia and reperfusion injury (Lane et ...studies in IL-10- deficient mice suggested that endogenous IL-10 exerted anti-inflammatory role during ... See full document

... result in an increase in membrane permeability or disruption of membrane integrity through peroxi- dation of lipids in mitochondria and cell membra- ne, and cause damage to proteins, ... See full document

... from the Center for Experimental Animals of Chongqing Medical University ...(China). The US National Institutes of Health Guidelines for Care and Use of Laboratory Animals were followed ... See full document

... retention of unfolded or misfolded proteins inside the ER lumen, which affects the physiological function of ER that results in ERS 25 ...important role in maintaining ER ... See full document

... roles in regulating multiple cellular and tissue processes including cellular proliferation, differentiation, growth, metabolism, and apoptosis (16, ...17). The basal level of c-myb protein is ... See full document

... 84 genes related to oxidative stress and antioxidant defense allowed us to evaluate the stimulus of ischemia and reperfusion on renal tissue in inbred ...mice. The ... See full document

... Transplantation of bone marrow mesenchymal stem cells decreases oxidative stress, apoptosis, and hippocampal damage in brain of a spontaneous stroke ... See full document

... limitations in our study. First, we used only the inhibitor wortmannin to investigate the role of PI3K/Akt signaling pathway in current ...Accordingly, the PI3K or Akt ... See full document

... by reperfusion (I/R) promotes multiple biological responses that cause tissue injury and organ ...include the generation of reactive oxygen species (ROS), the activation of ... See full document

... reviewed the various publications and selected serum lactate and LDH values as biochemical parameters in demonstrating the possible protective effects of both reperfusion injury ... See full document

... I/R injury of an elderly ...because the standard ischemic preconditioning method seemed to be ineffective in the case of old ...better in promoting ... See full document

... important role in hematopoiesis, host defense, inflammation and tissue ...into the circulation and stimulates liver cells to secrete acute phase proteins, playing a relevant role in ... See full document

... perimeter of 1.000 microns was determined on each slide. Within the perimeter, ten villi were randomly selected, and 100 epithelial cells were counted in 10 villi per slice for 5 treatment groups ... See full document

... μg of RNA was used for reverse transcription into ...runner in the MX3000P thermal cycler (Applied ...to the manufacture instructions in 96-well plates to detect the ... See full document

... evidence of injury in the kidney may indicate that injury in this organ was not severe enough to cause structural ...evidence of structural organ injury, the ... See full document

... one of three groups: 1) vehicle-treated sham group (SG); 2) vehicle-treated control group (CTG); and 3) sildenail citrate-treated group ...(SCG). The rats were anesthetised with ketamine hydrochloride ... See full document

... participate in the occurrence and development of many diseases through a variety of ...as apoptosis, necrosis, and ...coding genes 7,8 ... See full document