[PDF] Top 20 'Smoking genes': a genetic association study.

... strongest genetic association we found in our study with smoking status and smoking-related phenotypes was for polymor- phisms in CYP2A6, the gene encoding the principle nicotine C- ... See full document

... candidate genes, CDX1, FLT1 and RARG, contained SNPs that showed association with P-val- ...these genes are worth of scrutiny in further ...presumably genetic) heterogeneity, as in fact is ... See full document

... Bidirectional sequencing in the discovery sample allowed us to identify in the UCMA/GRP gene, fourteen SNPs already reported in the SNP database (NCBI), and five variants previously unknown: three were detected in the ... See full document

... that genetic variation in one component of the T1R2-T1R3 heterodimer may account for interindividual differences in the consumption of sweet foods, although this association was not reflected in modifi- ... See full document

... Sometimes, genetic association tests might be underpowered to detect obesity related genes using BMI ...genome-wide association study using both BMI (most significant SNP: P = ... See full document

... genome-wide association studies in the genetics of complex diseases, the contribution of certain IL23R variants to CD or UC is not sufficiently strong to explain the genetic background of IBD on its ... See full document

... our study are relatively high, and importantly, al- most all of the individuals were examined three times within ten ...2002), smoking is still not viewed as a “social ... See full document

... susceptibility genes is the study of polymorphisms in candi- date ...genes. Genetic association studies test whether a spe- cific genetic variant is more common in asthmatics ... See full document

... the association between gene variants and CVD events in the WGHS cohort and odds ratios (OR) and 95% confidence intervals (CI) were ...no), smoking (never, past, current), and family history of myocardial ... See full document

... host genes and the environment. There is evidence that besides genetic influences and individuals host susceptibility to infections, environmental factors may affect the clinical expression of ...large ... See full document

... the genetic relationship of genes expressed in the PSD with schizophrenia, a family-based association analysis of genetic variants in PSD genes such as DLG4, DLG1, PICK1 and MDM2, was ... See full document

... found genetic variants associated with atherosclerosis and cardiovascular risk in the general population ...marker genes such as C-Reactive Protein (CRP) [14,15], Interleucin-6 (IL6) [10], Interleucin-1 ... See full document

... Sample selection was carried out by simple random samp- ling of students based on the data provided by the Municipal Education Secretariat of Campo Verde, which, in the year 2012, had 1732 students attending the first ... See full document

... present study is explained not only by the method used for selecting the sample, which was composed of patients with early-stage BAC, but also by the fact that the nodular presentation is the most common radi- ... See full document

... this study analyzed data from 215 pre- school children, some limitations should be ...secondhand smoking in the home found was lower than that used to calculate the sample ...present study will be ... See full document

... committed to identifying an association between haplotypes of HLA class I and II molecules and the risk for the development of inhibitors. Hay et al. studied 176 hemophilia patients in England and found a higher ... See full document

... Prostate cancer (PCa) has become a major public health problem concern worldwide for its high morbidity and mortality levels. It is the second leading cause of cancer related to death in Europe, North America, Latin ... See full document

... present study is explained not only by the method used for selecting the sample, which was composed of patients with early-stage BAC, but also by the fact that the nodular presentation is the most common radi- ... See full document

... the study of individual susceptibility to cancer induced by the ...of genes responsible for determining risk is still not ...individual genes, since if genetic susceptibility is partially ... See full document

... quit smoking, 78% of whom went without smoking for at least seven consecutive ...of smoking cessation by category of variable included in the ...this association was reversed, with a lower PR ... See full document