Há décadas nosso grupo de pesquisa tem realizado uma extensiva busca de atividades biológicas de polissacarídeos sulfatados obtidos de macroalgas marinhas. Entretanto, uma nova linha de pesquisa vem ganhando destaque investigando a ação do polissacarídeo, xilana, extraído de sabugo de milho, sendo este um produto subutilizado pelo mercado agrícola e industrial. Atualmente trabalhos com xilana vêm demonstrando que este polímero possui inúmeras atividades biológicas, tais como antioxidante, antitumoral, antifúngica dentre outras. E para investigar mais sobre essas atividades a inserção da nanotecnologia na nossa pesquisa também tem sido testada.
No entanto, apesar de algumas atividades biológicas já terem sido descritas para esse polímero, escassos são os trabalhos realizados sobre a atividade antiparasitária, principalmente frente ao parasita T. cruzi. Este trabalho visa ajudar na elucidação dos mecanismos de ação como também oferecer no futuro uma nova alternativa terapêutica para a doença de Chagas.
Durante o desenvolvimento deste trabalho tive a oportunidade de aprimorar e aprender novas técnicas nos mais diferentes campos de atuação (parasitologia, farmacologia, bioquímica, cultura de célula). Além disto, esta experiência me propôs conhecer novos laboratórios e a interagir com vários grupos de pesquisas localizados aqui na UFRN.
Com relação à produção científica, ao longo do doutorado, participei de vários congressos e encontros com submissão de resumos científicos, colaborei com a orientação de alunos de iniciação científica e de mestrado. Além disso, também fiz parte na colaboração de experimentos de Dissertações e Teses do próprio laboratório. Após a conclusão dessa etapa acadêmica, tenho como projeto para o futuro, continuar com os estudos em um futuro pós-doutorado aqui no Brasil ou no Exterior, procurando sempre a possibilidade de aprovação em concursos docentes em Instituições de Ensino ou Pesquisa na minha área de atuação, que é a Farmácia. Ao longo desse trajeto houve vários percalços que poderiam promover a desistência de chegar ao objetivo final deste trabalho, mas com a perseverança e apoio de familiares, amigos e principalmente do meu orientador/amigo Dr. Hugo Rocha pude realizar o cumprimento de mais esta meta.
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