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2.PERFIL CLÍNICO-EPIDEMIOLÓGICO

3. FATORES DE RISCO PARA TB 1 Febre recentemente:

( )Sim ( )Não

Temperatura no momento da entrevista:

________________________ 3.2 Gripe recentemente:

( )Sim ( )Não

3.3 Diagnóstico de Pneumonia recentemente:

( )Sim ( )Não

quanto tempo?

____________________________________________

3.4 Diagnóstico de Asma recentemente:

121     quanto tempo? ____________________________________________

3.5 Diagnóstico de Doença Pulmonar Obstrutiva Crônica

recentemente:

( )Sim ( )Não

quanto tempo? ________________________________________ 3.6 Diagnóstico de Doenças respiratórias ocupacionais (exposição a gases, vapores, fumos e poeiras no ambiente de trabalho) recentemente:

( )Sim ( )Não

3.7 Realização de tratamento para alguma doença respiratória?

( )Sim ( )Não

quanto tempo?________ qual doença?_______________________ 3.8 Tratamento prolongado com corticosteroides?

( )Sim ( )Não

quanto tempo?_______qual ?______________________________ 3.9 Tratamento com drogas imunossupressoras (período superior a um mês);

( )Sim ( )Não

122 

  

3.10 Diagnóstico de alguma doença renal crônica?

( )Sim ( )Não

qual? ____________________________________________ 3.11 Realização de hemodiálise?

( )Sim ( )Não

quanto tempo?______________

3.12 Diagnóstico de alguma como: Artrite reumatoide, lúpus, Tireoidite de Hashimoto, Vitiligo, Diabetes Mellitus, doença de Crohn, esclerose múltipla, câncer, etc.

( )Sim ( )Não qual? ____________________________________________ 3.13 Diagnóstico de HIV? ( )Sim ( )Não quanto tempo?________________________________________ 3.14 Tabagismo: ( )Sim ( )Não quanto tempo?________________________________________ 3.15 Etilismo:

( ) Não ( ) 2 vezes na semana

( ) 1 vez na semana ( ) 3 vezes na semana

123 

  

3.16. Pratica exercícios físicos regularmente?

( )Sim ( )Não

quanto tempo?________________________________________ 3.17 Diagnóstico de anemias?

( )Sim ( )Não

qual? ____________________________________________ 3.18 Realização de alguma dieta alimentar?

( )Sim ( )Não

tempo?________________________________________ 3.19 Uso de algum esteroide anabolizante?

( )Sim ( )Não

qual? ____________________________________________ 3.20 Uso de alguma suplementação alimentar?

( )Sim ( )Não

qual? ____________________________________________ 3.21 Perda de peso acentuada recentemente?

( )Sim ( )Não

quanto ?______________________________________________ 3.21 Perda de apetite acentuada recentemente ou uso de algum medicamento para reduzir o apetite?

124     ( )Sim ( )Não qual? ____________________________________________ 3.21 Presença de suores noturnos?

( )Sim ( )Não

quanto tempo?________________________________________

3.22 Presença de calafrios, fadiga ou dor torácica?

( )Sim ( )Não

qual? ____________________________________________ 3.23 Alguma dificuldade para respirar (dispneia)?

( )Sim ( )Não

quanto tempo?________________________________________ 3.24 Presença de rouquidão na voz?

( )Sim ( )Não

quanto tempo?________________________________________ 3.25 Diagnóstico de laringite recentemente?

( )Sim ( )Não

125 

  

3.25 Uso de medicamentos como: prednisona, anti-TNF-Į,

ciclosporina, Azatiprina, a 6-Mercaptopurina (Purinethol), o

Metotrexate (Metotrexate), Betametasona, Dexametasona,

Triancinolona, etc.

( )Sim ( )Não

qual? ______________________quanto tempo?

________________

3.26. Apresentou desnutrição recentemente?

( )Sim ( )Não

quanto tempo?________________________________________ 3.27 Uso de drogas ilícitas (injetáveis, inaladas, fumadas, anfetaminas):

( )Sim ( )Não

qual? ______________________quanto tempo?

________________

3.28. Apresenta parceiro (a) sexual fixo?

( )Sim ( )Não

quanto tempo?________________________________________ 3.29. Apresenta múltiplos parceiros (as) sexual?

( )Sim ( )Não

126 

  

3.30 Estilo de vida sedentário:

( )Sim ( )Não

3.30 Estilo de vida saudável:

( )Sim ( )Não

Qual atividade física?______________________________________ ___________________________________________________

Assinatura/CPF

___________________________________________________ Assinatura do pesquisador

REFERÊNCIAS

ACHKAR, J. M.; DONG, Y.; HOLZMAN, R. S.; BELISLE, J. et al. Mycobacterium tuberculosis malate synthase- and MPT51-based serodiagnostic assay as an adjunct to rapid identification of pulmonary tuberculosis. Clin Vaccine Immunol, v. 13, n. 11, p. 1291-3, Nov, 2006.

AGGERBECK, H.; GIEMZA, R.; JOSHI, P.; TINGSKOV, P. N. et al. Randomised clinical trial investigating the specificity of a novel skin test (C-Tb) for diagnosis of M. tuberculosis infection. PLoS One, v. 8, n. 5, p. e64215, 2013.

ALTINK, H. Tuberculosis in the british empire. The University of York, v. 3, n. 6, 2013.

AOSHI, T.; NAGATA, T.; SUZUKI, M.; UCHIJIMA, M. et al. Identification of an HLA-A*0201-restricted T-cell epitope on the

MPT51 protein, a major secreted protein derived from

Mycobacterium tuberculosis, by MPT51 overlapping peptide screening. Infect Immun, v. 76, n. 4, p. 1565-71, Apr, 2008.

BAUMANN, R.; KAEMPFER, S.; CHEGOU, N. N.; OEHLMANN, W. et al. Serologic diagnosis of tuberculosis by combining Ig classes against selected mycobacterial targets. J Infect, v. 69, n. 6, p. 581-9, Dec, 2014.

BESEN, A.; STAUB, G. J.; SILVA, R. M. Clinical, radiological, and laboratory characteristics in pulmonary tuberculosis patients: comparative study of HIV-positive and HIV-negative inpatients at a referral hospital. J Bras Pneumol, v. 37, n. 6, p. 768-75, Nov-Dec, 2011.

BODMER, T.; STROHLE, A. Diagnosing pulmonary tuberculosis with the Xpert MTB/RIF test. J Vis Exp, n. 62, p. e3547, 2012.

BRASIL. Manual técnico para o controle da tuberculose: cadernos de atenção básica. 6ºed. Brasília: Ministério da Saúde, 2002.

______. Manual de recomendações para o controle da tuberculose no Bras. Departamento de Vigilância Epidemiológica, p. 284, 2011.

CHANG, K.; LU, W.; WANG, J.; ZHANG, K. et al. Rapid and effective diagnosis of tuberculosis and rifampicin resistance with Xpert MTB/RIF assay: a meta-analysis. J Infect, v. 64, n. 6, p. 580-8, Jun, 2012.

CONNELL, T. G.; TEBRUEGGE, M.; RITZ, N.; BRYANT, P. A. et al. Indeterminate interferon-gamma release assay results in children. Pediatr Infect Dis J, v. 29, n. 3, p. 285-6, Mar, 2010.

CUEVAS, L. E.; BROWNING, R.; BOSSUYT, P.; CASENGHI, M. et

al. Evaluation of tuberculosis diagnostics in children: 2.

Methodological issues for conducting and reporting research evaluations of tuberculosis diagnostics for intrathoracic tuberculosis

in children. Consensus from an expert panel. J Infect Dis, v. 205 Suppl 2, p. S209-15, May 15, 2012.

DAVIDOW, A.; KANAUJIA, G. V.; SHI, L.; KAVIAR, J. et al. Antibody profiles characteristic of Mycobacterium tuberculosis infection state. Infect Immun, v. 73, n. 10, p. 6846-51, Oct, 2005.

DE SOUSA, E. M.; DA COSTA, A. C.; TRENTINI, M. M.; DE ARAUJO FILHO, J. A. et al. Immunogenicity of a fusion protein containing immunodominant epitopes of Ag85C, MPT51, and HspX from Mycobacterium tuberculosis in mice and active TB infection. PLoS One, v. 7, n. 10, p. e47781, 2012.

DEMISSIE, A.; LEYTEN, E. M.; ABEBE, M.; WASSIE, L. et al. Recognition of stage-specific mycobacterial antigens differentiates between acute and latent infections with Mycobacterium tuberculosis. Clin Vaccine Immunol, v. 13, n. 2, p. 179-86, Feb, 2006.

DORMAN, S. E. New diagnostic tests for tuberculosis: bench, bedside, and beyond. Clin Infect Dis, v. 50 Suppl 3, p. S173-7, May 15, 2010.

FAVROT, L.; LAJINESS, D. H.; RONNING, D. R. Inactivation of the Mycobacterium tuberculosis antigen 85 complex by covalent, allosteric inhibitors. J Biol Chem, v. 289, n. 36, p. 25031-40, Sep 5, 2014.

FENG, X.; XIU, B.; CHEN, K.; YANG, X. et al. Enhanced

serodiagnostic utility of novel Mycobacterium tuberculosis

polyproteins. J Infect, v. 66, n. 4, p. 366-75, Apr, 2013.

FLORES, L. L.; STEINGART, K. R.; DENDUKURI, N.; SCHILLER, I. et al. Systematic review and meta-analysis of antigen detection tests for the diagnosis of tuberculosis. Clin Vaccine Immunol, v. 18, n. 10, p. 1616-27, Oct, 2011.

FONTAN, P.; ARIS, V.; GHANNY, S.; SOTEROPOULOS, P. et al. Global transcriptional profile of Mycobacterium tuberculosis during THP-1 human macrophage infection. Infect Immun, v. 76, n. 2, p. 717-25, Feb, 2008.

GLAZIOU, P.; SISMANIDIS, C.; FLOYD, K.; RAVIGLIONE, M. Global epidemiology of tuberculosis. Cold Spring Harb Perspect Med, v. 5, n. 2, p. a017798, Feb, 2015.

GOUGH, A.; KAUFMAN, G. Pulmonary tuberculosis: clinical features and patient management. Nurs Stand, v. 25, n. 47, p. 48-56; quiz 58, Jul 27-Aug 2, 2011.

KASHYAP, R. S.; SAHA, S. M.; NAGDEV, K. J.; KELKAR, S. S. et al. Diagnostic markers for tuberculosis ascites: a preliminary study. Biomark Insights, v. 5, p. 87-94, 2010.

KENNAWAY, C. K.; BENESCH, J. L.; GOHLKE, U.; WANG, L. et al. Dodecameric structure of the small heat shock protein Acr1 from

Mycobacterium tuberculosis. J Biol Chem, v. 280, n. 39, p. 33419- 25, Sep 30, 2005.

KIK, S. V.; DENKINGER, C. M.; JEFFERSON, C.; GINNARD, J. et al. Potential market for novel tuberculosis diagnostics: worth the investment? J Infect Dis, v. 211 Suppl 2, p. S58-66, Apr 1, 2015.

KNECHEL, N. A. Tuberculosis: pathophysiology, clinical features, and diagnosis. Crit Care Nurse, v. 29, n. 2, p. 34-43; quiz 44, Apr, 2009.

LAGRANGE, P. H.; THANGARAJ, S. K.; DAYAL, R.; DESHPANDE, A. et al. A toolbox for tuberculosis (TB) diagnosis: an Indian multi- centric study (2006-2008); evaluation of serological assays based on PGL-Tb1 and ESAT-6/CFP10 antigens for TB diagnosis. PLoS One, v. 9, n. 5, p. e96367, 2014.

LIENHARDT, C.; FIELDING, K.; HANE, A. A.; NIANG, A. et al. Evaluation of the prognostic value of IFN-gamma release assay and tuberculin skin test in household contacts of infectious tuberculosis cases in Senegal. PLoS One, v. 5, n. 5, p. e10508, 2010.

MAIGA, M.; ABAZA, A.; BISHAI, W. R. Current tuberculosis diagnostic tools & role of urease breath test. Indian J Med Res, v. 135, n. 5, p. 731-6, May, 2012.

MELO CARDOSO ALMEIDA, C.; VASCONCELOS, A. C., JR.; KIPNIS, A.; ANDRADE, A. L. et al. Humoral immune responses of

tuberculosis patients in Brazil indicate recognition of Mycobacterium tuberculosis MPT-51 and GlcB. Clin Vaccine Immunol, v. 15, n. 3, p. 579-81, Mar, 2008.

MENZIES, D.; PAI, M.; COMSTOCK, G. Meta-analysis: new tests for the diagnosis of latent tuberculosis infection: areas of uncertainty and recommendations for research. Ann Intern Med, v. 146, n. 5, p. 340- 54, Mar 6, 2007.

NORTH, R. J.; JUNG, Y. J. Immunity to tuberculosis. Annu Rev Immunol, v. 22, p. 599-623, 2004.

PARSONS, L. M.; SOMOSKOVI, A.; GUTIERREZ, C.; LEE, E. et al. Laboratory diagnosis of tuberculosis in resource-poor countries: challenges and opportunities. Clin Microbiol Rev, v. 24, n. 2, p. 314- 50, Apr, 2011.

PHUNPAE, P.; CHANWONG, S.; TAYAPIWATANA, C.;

APIRATMATEEKUL, N. et al. Rapid diagnosis of tuberculosis by identification of Antigen 85 in mycobacterial culture system. Diagn Microbiol Infect Dis, v. 78, n. 3, p. 242-8, Mar, 2014.

RAMAKRISHNAN, L. Revisiting the role of the granuloma in tuberculosis. Nat Rev Immunol, v. 12, n. 5, p. 352-66, May, 2012.

RINKE DE WIT, T. F.; BEKELIE, S.; OSLAND, A.; WIELES, B. et al. The Mycobacterium leprae antigen 85 complex gene family:

identification of the genes for the 85A, 85C, and related MPT51 proteins. Infect Immun, v. 61, n. 9, p. 3642-7, Sep, 1993.

RYU, Y. J. Diagnosis of pulmonary tuberculosis: recent advances and diagnostic algorithms. Tuberc Respir Dis (Seoul), v. 78, n. 2, p. 64-71, Apr, 2015.

SHAMS, H.; WEIS, S. E.; KLUCAR, P.; LALVANI, A. et al. Enzyme- linked immunospot and tuberculin skin testing to detect latent tuberculosis infection. Am J Respir Crit Care Med, v. 172, n. 9, p. 1161-8, Nov 1, 2005.

SILVA, B. D.; DA SILVA, E. B.; DO NASCIMENTO, I. P.; DOS REIS, M. C. et al. MPT-51/CpG DNA vaccine protects mice against Mycobacterium tuberculosis. Vaccine, v. 27, n. 33, p. 4402-7, Jul 16, 2009.

SINGER-LESHINSKY, S. Pulmonary tuberculosis: Improving

diagnosis and management. Jaapa, v. 29, n. 2, p. 20-5, Feb, 2016.

STEINGART, K. R.; HENRY, M.; NG, V.; HOPEWELL, P. C. et al. Fluorescence versus conventional sputum smear microscopy for tuberculosis: a systematic review. Lancet Infect Dis, v. 6, n. 9, p. 570-81, Sep, 2006.

TORTOLI, E.; RUSSO, C.; PIERSIMONI, C.; MAZZOLA, E. et al. Clinical validation of Xpert MTB/RIF for the diagnosis of

extrapulmonary tuberculosis. Eur Respir J, v. 40, n. 2, p. 442-7, Aug, 2012.

VAN'T HOOG, A. H.; COBELENS, F.; VASSALL, A.; VAN KAMPEN, S. et al. Optimal triage test characteristics to improve the cost- effectiveness of the Xpert MTB/RIF assay for TB diagnosis: a decision analysis. PLoS One, v. 8, n. 12, p. e82786, 2013.

WARRIER, T.; TROPIS, M.; WERNGREN, J.; DIEHL, A. et al. Antigen 85C inhibition restricts Mycobacterium tuberculosis growth through disruption of cord factor biosynthesis. Antimicrob Agents Chemother, v. 56, n. 4, p. 1735-43, Apr, 2012.

WHO. Global Tuberculosis Report. World Health Organization, 2015.

WILSON, R. A.; MAUGHAN, W. N.; KREMER, L.; BESRA, G. S. et al. The structure of Mycobacterium tuberculosis MPT51 (FbpC1) defines a new family of non-catalytic alpha/beta hydrolases. J Mol Biol, v. 335, n. 2, p. 519-30, Jan 9, 2004.

ZHANG, X.; SU, Z.; ZHANG, X.; HU, C. et al. Generation of Mycobacterium tuberculosis-specific recombinant antigens and evaluation of the clinical value of antibody detection for serological diagnosis of pulmonary tuberculosis. Int J Mol Med, v. 31, n. 3, p. 751-7, Mar, 2013.

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