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EMTr de baixa frequência aplicada sobre o córtex motor não lesado associada a fisioterapia motora reduz a excitabilidade medular assim como a espasticidade do membro superior de pacientes pós AVE em fase crônica. Pode-se sugerir o uso da EMTr como terapia complementar à fisioterapia, por se tratar de uma técnica de modulação cortical, segura, indolor e não invasiva.

Considera-se que os resultados do presente estudo contribuíram para a hipótese de que estratégias de facilitação da neuroplasticidade podem ser utilizadas nas clínicas de fisioterapia, com o propósito de maximizar os efeitos terapêuticos do programa de reabilitação. O que poderia levar à recuperação precoce e efetiva dos pacientes e reduzir os custos com reabilitação. Entretanto é importante salientar que os possíveis mecanismos envolvidos nos efeitos observados ainda são hipotéticos, por isso mais ensaios clínicos randomizados com follow-up são necessários para esclarecer os mecanismos neurofisiológicos subjacentes a estes efeitos.

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IBLIOGRÁFICAS

ADLER, S. S.; BECKERS, D.; BUCK, M. Facilitação neuro-muscular

proprioceptiva: um guia ilustrado. 2ª Ed. São Paulo: Manole, 2007.

ALAGONA, G.; BELLA, R.; FERRI, R.E. Transcranial magnetic stimulation in Alzheimer disease: motor córtex excitability na cognitive severity. Neurosci letters, v. 314, n.1, p. 57-60, nov. 2001.

ANGEL, R. W.; HOFFMANN, W. W. The H reflex in normal, spastic and rigid subjects. Arch. Neurol. v. 8, p. 591-6, 1963.

ANSARI, N.N.; NAGHDI, S.; MASHAYEKHI, M. et al. Intra-rater reliability of the Modified Modified Ashworth Scale (MMAS) in the assessment of upper-limb muscle spasticity. NeuroRehabilitation, v. 31, n. 2, p. 215–22, 2012.

ASHWORTH, B. Preliminary trial of carisoprodol in multiple sclerosis. Practicioner, v. 192, p. 540-542, 1964.

ASSOCIAÇÃO BRASILEIRA DE MEDICINA FÍSICA E REABILITAÇÃO. LEITÃO, A.

et al. Espasticidade: Avaliação Clínica. Projeto Diretrizes. 2006a. Disponível em:

<http://www.projetodiretrizes.org.br/5_volume/18-Espasticid.pdf> Acessado em: 20/01/2013.

ASSOCIAÇÃO BRASILEIRA DE MEDICINA FÍSICA E REABILITAÇÃO. FONSECA, A.P.C. et al. Espasticidade: Tratamento por Meio de Medicina Física. Projeto

Diretrizes. 2006b. Disponível em: <http://www.projetodiretrizes.org.br/6_volume/20-

Espasticidtratporme.pdf> Acessado em: 20/01/2013.

BAKHEIT, A. M.; JALINOUS, R.; FREESTON, I. L. The relation between Ashworth scale scores and the excitability of the alpha motor neurones in patients with post-stroke muscle spasticity. J. Neurol Neurosurg Psychiatry, v. 74, n. 5, p. 646-8, 2003.

BARKER, A. T.; JALINOUS, R.; FREESTON, I. L. Non-invasive magnetic stimulation of human motor cortex. Lancet, v. 1,p. 1106–07, 1985.

BHAKTA, B. B. Management of spasticity in stroke. Br. Med Bull., v. 56, p. 476-85, 2000.

BLISS, T. V. P.; LOMO, T. Long-lasting potentiation of synaptic transmission in the dentate area of the anaesthetized rabbit following stimulation of the perforant path. J

Physiol, v. 232(2), p. 331–356, 1973.

BOBATH, B. Hemiplegia no adulto: avaliação e tratamento. 3aed. São Paulo: Manole, 1980.

BOHANNON, R. W. Simple clinical meansures. Phy. Ther., v. 67, n. 12, p. 1845-50, 1987.

BOHANNON, R. W.; SMITH, M. B. Interrater reliability of a modified Ashworth scale of muscle spasticity. Phys. Ther., v. 67, p. 206–207, 1987.

BOLOGNINI, N.; PASCUAL-LEONE, A.; FREGNI, F. Using non-invasive brain stimulation to augment motor training-induced plasticity. J. Neuroeng Rehabil, v. 17, p. 6-8, 2009.

BRUCKI, S. M. D.; NITRINI, R.; CARAMELLI, P. et al. Sugestões para o uso do Mini-Exame do Estado Mental no Brasil. Arq Neuropsiq., v. 61, p. 777-81, 2003. BURKE, R. E. Sir Charles Sherrington's the integrative action of the nervous system: a centenary appreciation. Brain, v. 130, p-887-94, 2007.

CADERNOS DE INFORMAÇÃO DE SAÚDE – DATASUS. Brasília, 2010. <http://tabnet.datasus.gov.br/tabdata/cadernos/cadernosmap.htm>. Acessado em: 30.01.2013.

CANEDA, M. A. G.; FERNANDES, J. G.; ALMEIDA, A. G. et al. Confiabilidade de escalas de comprometimento neurológico em pacientes com acidente vascular cerebral. Arq. Neuropsiq., p. 64, n. 3A, p. 690-7, 2006.

CENTONZE, D. KOCH, G.; VERSACE, V. et al. Repetitive transcranial magnetic stimulation of the motor cortex ameliorates spasticity in multiple sclerosis.

Neurology. v. 68, p. 1045-1050, 2007.

CHANG, W. H.; KIM, Y-H.; BANG, O. Y. et al. Long-term effects of rTMS on motor recovery in patients after subacute stroke. J. Rehabil Med., v. 42, p. 758–764, 2010. CHAPMAN, C. E.; WIESENDANGER, M. Physiological and anatomical basis of spasticity: review. Physiother Can., v. 34, p. 125-136, 1982.

CHAVES, M. L.F. Acidente vascular encefálico: conceituação e fatores de risco.

Rev. Bras. Hipertens., v. 4, p. 372-382, 2000.

CHEN, H.; EPSTEIN, J.; STERN, E. Neural plasticity after acquired brain injury: evidence from functional neuroimaging. PM. & R., v. 2, n. 12, p. 306–312, 2010. CONFORTO, A. B.; MARIE, S.K.N.; COHEN, L.G. et al. Estimulação Magnética Transcraniana. Arquiv. Neuropsiquiatr, v. 61, n. 1, p. 146-152, 2003.

CONFORTO, A. B.; FERREIRO, K. N.; TOMASI, C. et al. Effects of Somatosensory Stimulation on Motor Function After Subacute Stroke. Neurorehabil Neural Repair, v. 24, n. 3, p. 263–272, 2010.

CONSENSO NACIONAL SOBRE ESPASTICIDADE. Diretrizes para diagnósticos e tratamentos. Sociedade Brasileira Medicina Física e Reabilitação, São Paulo 2001.

COUSINS, E.; WARD, A.B.; ROFFE, C. et al. Quantitative measurement of poststroke spasticity and response to treatment with botulinumtoxin: a 2-patient case report. Phys. Ther., v. 89, n. 7, p. 688–697, 2009.

CRAMER, S. C.; RILEY, J. D. Neuroplasticity and brain repair after stroke. Current

Opinion in Neurology, v. 21 (1), p 76-82. 2008.

DANCAUSE, N.; NUDO, R. J. Shaping plasticity to enhance recovery after injury.

Progress in Brain Research, v. 192, p. 273–295, 2011.

DE LA PAZ, R. L. Cerebrovascular disease. Am. J. Neuroradiol, v. 28, p. 1197– 1199, 2007.

DE RIDDER, D.; VERSTRAETEN, E.; VAN-DER-KELEN, K. et al. Transcranial magnetic stimulation fot tinnitus: influence of tinnitus duration on stimulation parameter choice and maximal tinnitus suppression. Otol. Neurotol, v. 26, n. 4, p. 616-619, 2005.

DELWAIDE, P. J.; OLIVIER, E. Short-latency autogenic inhibition (Ib inhibition) in human spasticity. Journal of Neurology Neurosurgery and Psychiatry, v. 51, p. 1546–1550, 1988.

DROMERICK, A. W.; EDWARDS, D. F.; HAHN, M. Does the application of constraint-induced movement theraphy during rehabilitation reduce arm impairment after ischemic stroke? Stroke, v. 31, n. 12, p. 2984-8, dez. 2000.

EMARA, T. H.; MOUSTAFA, R. R.; ELNAHAS, N. M.; et al. Repetitive transcranial magnetic stimulation at 1Hz and 5Hz produces sustained improvement in motor function and disabilityafter ischaemic stroke. European Journal of Neurology, v. 17, p. 1203–1209, 2010.

FERBERT, A.; PRIORI, A.; ROTHWELL, J. C. et al. Interhemispheric inhibition of the human motor cortex. Journal of Physiology, v. 453, p. 525–546, 1992.

FOX, P.; INGHAM, R.; GEORGE, M. S. et al. Imaging human intra-cerebral connectivity by PET during TMS. Neuroreport, v. 8, p. 2787–91, 1997.

FREGNI, F.; MARCOLIN, M. A. O uso da estimulação cerebral na terapêutica dos transtornos neuropsiquiátricos: o papel da estimulação magnética transcraniana na prática clínica. Rev. Psiquiatria Clínica, v. 31, n. 5, p. 221-230, 2011.

FREGNI, F.; SIMON, D. K.; WU, A. et al. Non-invasive brain stimulation for Parkinson's disease: a systematic review and meta-analysis of the literature. J

Neurol Neurosurg Psychiatry, v. 76, n. 12, p. 1614-23, 2005.

FREGNI, F.; BOGGIO, P. S.; BRUNONI, A. R. Neuromodulação Terapêutica:

Princípios e avanços da estimulação cerebral não invasiva em neurologia, reabilitação, psiquiatria, e neuropsicologia. 1ª Ed. São Paulo: Sarvier, 2011.

GAUTHIER, L. V. TAUB, E.; MARK, V. W. et al. Atrophy of spared gray matter tissue predcys poorer motor recovery and rehabilitation response in chronic stroke. Stroke, v. 43, n. 2, p. 453-7, nov. 2011.

GILES, M. F.; ROTHWELL, P. M. Measuring the prevalence of stroke.

Neuroepidemiology, v. 30, p. 205-206, 2008.

GOLDSTEIN, E. M. Spasticity management: an overview. J. Child Neurol, v. 16, p. 16–23, 2001.

GORASSINI, M. A.; KNASH, M. E.; HARVEY, P. J. et al. Role of motoneurons in the generation of muscle spasms after spinal cord injury. Brain, v. 127, n. 10, p. 2247- 58, 2004

GUSTAFSSON, B.; WIGSTROM, H. Physiological mechanisms underlying long-term potentiation. Trends Neurosci, v.11, p. 156–62, 1988.

HARRIS, J. E.; ENG, J. J. Paretic upper-limb strength best explains arm activity in people with stroke. Phys. Ther., v. 87, n.1, p. 88-97, 2007.

HASEY, G. Transcranial magnetic stimulation in the treatment of mood disorder: a review and comparison with electroconvulsive therapy. Can J. Psychiatry, v. 46, p. 720–7, 2001.

HOF, A. L. Changes in muscles and tendons due to neural motor disorders: implications for therapeutic intervention. Neural Plast., v. 8, p. 71-81, 2001.

HOSP, J. A.; LUFT, A. R. Cortical plasticity during motorlearning and recovery after ischemic stroke. Neural Plasticity, v. 2011, n. id. 871296, p. 1-9, 2011.

HUANG, C. Y.; WANG, C. H.; HWANG, I. S. Characterization of the mechanical and neural components of spastic hypertonia with modified H reflex. J. Electromyogr

Kinesiol, v.16, n.4, p. 384-91, 2006

HUMMEL, F. C.; COHEN, L. G. Non-invasive brain stimulation: a new strategy to improve neurorehabilitation after stroke? Lancet Neurol, v. 5, p. 708-712, 2006

JOHNSTON, M. V. Plasticity in the developing brain: implications for rehabilitation. Developmental. Disabilities Research Reviews, v. 15, n. 2, p. 94–101, 2009.

KANDEL, E. R.; SCHWARTZ, J. H.; JESSELL, T. M. Princípios da Neurociência. São Paulo: Manole, 2003.

KAKUDA, W.; ABO, M.; KOBAYASHI, K. et al. Anti-spastic effect of low-frequency rTMS applied with occupational therapy in post-stroke patients with upper limb hemiparesis. Brain Inj., v.25, n.5, p. 496-502, 2011

KATZ, R.; PIERROT-DESEILLIGNY, E. Recurrent inhibition in humans. Progress in

KATZ, R. T.; RYMER, Z. Spastic hipertonia: mechanismis and measurement. Arch.

Phys. Med. Rehabil, v. 70, p. 144-55. 1989.

KHERDR, E. M.; ROTHWELL, J.C.; SHAWKY, O.A. et al. Effect of daily repetitive transcranial mmagnetic stimulation on motor performance in parkinson’s disease.

Mov. disord., v. 21, n.12, p. 2201-2205, 2006

KLOTZ, T. BORGES, H. C.; MONTEIRO, V. C. et al. Tratamento fisioterapêutico do ombro doloroso de pacientes hemiplégicos por acidente vascular encefálico - revisão da literatura. Rev. Acta fisiatria, v. 13, n. 1, p. 12–6, 2006

KOBAYASHI, M,; PASCUAL-LEONE, A. Transcranial magnetic stimulation in neurology. Lancet Neurol, v. 2, p. 145–56, 2003.

KOLOMINSKY-RABAS, P. L.; WEBER, M.; GEFELLER, O. et al. Epidemiology of ischemic stroke subtypes according to the TOAST criteria: incidence, recurrence, and long-term survival in ischemic stroke subtypes: a population-based study. Stroke, v. 32, p. 2735-2740, 2001.

KONINKLIJK NEDERLANDS GENOOTSCHAP VOOR FYSIOTHERAPIE (KNGF). Royal Dutch Society for Physical Therapy, 2004.

KUMRU, H.; MURILLO, N.; SAMSO, J.V. et al. Reduction of spasticity with repetitive transcranial magnetic stimulation in patients with spinal cord injury. Neurorehabil

Neural Repair, v. 24, n. 5, p. 435-41, 2010.

KWAKKEL, G.; KOLLEN, B. J.; WAGENAAR, R. C. Long-term effects of intensity of upper and lower limb training following stroke: a randomised trial. J. Neurol

Neurosurg Psychiatry, v. 72, p. 473-479, 2002.

KWAKKEL, G.; KOLLEN, B.; LINDEMAN, E. Understanding the pattern of functional recovery after stroke: facts and theories. Restor Neurol Neurosci, v. 22, p. 281–99, 2004.

LAI, S. M.; STUDENSKI, S.; DUNCAN, P.W. et al. Persisting consequences of stroke measured by the Stroke Impact Scale. Stroke, v. 33, p. 1840-1844, 2002

LANCE, J. W. The control of muscle tone, reflexes, and movement: Robert Wartenberg Lecture. Neurology, v. 30, p. 1303–1313, 1980.

LANNIN, N. A.; CUSICK, A.; MCCLUSKEY, A. et al. Effects of splinting on wrist contracture after stroke: A randomized controlled trial. Stroke, v. 38, p. 111-116, 2007.

LAVADOS, P. M.; HENNIS, A. J. M.; FERNANDES, J. G. et al. Stroke Epidemiology, prevention, and management strategies at a regional level: Latin America and Caribbean. Lancet neurology, v. 6, n. 4, p. 362-72, abr. 2007.

LEE, S. U.; BANG, M. S.; HAN, T. R. Effect of cold air therapy in relieving spasticity: applied to spinalized rabbits. Spinal Cord., v.40, p. 167-73, 2002

LEFAUCHEUR, J. P.; FENELON, G.; MENARD-LEFAUCHEUR, I. et al. Low- frequency repetitive TMS of premotor cortex can reduce painful axial spasm in generalized secondary distonia: a pilot study of tree patients. Neurophysiol clin., v. 34, p. 141-145, 2004.

LEVIN, M. F.; PANTURIN, E. Sensoriomotor integration for functional recovery and the Bobath approach. Motor control, v. 15, n. 2, p. 285-301, abr. 2011.

LINACRE, J. M.; HEINEMANN, A.W.; WRIGHT, B.D. et al. The structure and stability of the Functional Independence Measure. Arch. Phys. Med. Rehabil, v.75, p. 127-32, 1994.

LIN, K-C.; CHUNG, H-Y.; WU, C-Y. et al. Constraint-induced therapy versus control intervention in patients with stroke: a functional magnetic resonance imaging study.

American Journal of physical medicine & rehabilitation, v. 89, n. 3, p.177-85,

mar. 2010.

LUM, P. S.; MULROY, S.; AMDUR, R. L. et al. Gains in upper extremity function after stroke via recovery or compensation: potential differential effects on amount of real- wordl limb use. Topics in stroke rehabilitation, v. 16, n. 4, p. 237-53, 2009.

LUNDSTROM, E.; TERENT, A.B.J. Prevalence of disabling spasticity 1 year after first-ever stroke. European Journal of Neurology. 2008;15:533–9.

MACHADO, S.; VELASQUES, B.; PAES, F. et al. Estimulação magnética transcraniana : aplicações na reabilitação de Acidente Vascular Cerebral. Revista

Neurociências, 19(2):339–48. 2011.

MAHONEY, F.L.; BARTHEL, D. Functional evaluations the Barthel Index. Maryland

Stated Med. J., v. 14, p. 61-5, 1965.

MANN, U.; LONNECKER, S.; STEINHOFF, B.J. et al. Effects of antiepileptic drugs on motor cortex excitability in humans: a transcranial magnetic stimulation study.

Ann Neurol, v. 40, p. 367–78, 1996.

MAYNARD, F. M.; KARUNAS, R. S.; WARING, W. P. Epidemiology of spasticity following traumatic spinal cord injury. Archives of Physical Medicine and

Rehabilitation, v. 71, p. 566–569, 1990

MEUNIER, S.; PIERROT-DESEILLIGNY, E. Cortical control of presynaptic inhibition of Ia afferents in humans. Exp Brain Res, v.119(4), p. 415–26, 1998.

MINISTÉRIO DA SAÚDE. Acidente vascular cerebral (AVC). Brasília, 2010. http://www.brasil.gov.br/sobre/saude/saude-do-idoso/acidente-vascular-cerebral-avc. Acessado em: 30.01.2013.

MINISTÉRIO DA SAÚDE. DATASUS. Ministério da saúde. Datasus. Mortalidade – Brasil. Óbitos p/ ocorrência por sexo segundo Causa – CID-BR-10. Available from URL: www.datasus.gov.br [Informações de saúde: estatísticas vitais: mortalidade e nascidos vivos: mortalidade geral – desde 1996: Re. 2013.

MIYAZAKI, E. G.; ROSA, T.S.; NASCIMENTO, A.P.H. et al. Influência da estimulação de tono muscular e controle motor em hemiplégicos. Revista

Intellectus, v. 4, n. 5, 2008.

MOREIRA, A. L.; KIMAID, P. A. T. Espasticidade. Cap. 25. In. FREGNI, F.; BOGGIO, P. S.; BRUNONI, A. R. Neuromodulação Terapêutica: Princípios e avanços da

estimulação cerebral não invasiva em neurologia, reabilitação, psiquiatria, e neuropsicologia. 1ª Ed. São Paulo: Sarvier, 2011.

MORI, F.; KOCH, G.; FOTI, C. et al. The use of repetitive transcranial magnetic stimulation (rTMS) for the treatment of spasticity. Progress in Brain Research, v. 175, 2009.

MORI, F.; CODECA, C.; KUSAYANAGI, H. et al. Effects of intermittent theta burst stimulation on spasticity in patients with multiple sclerosis. European Journal of

Neurology, v. 17: p. 295–300, 2010

MURASE, N.; DUQUE, J.; MAZZOCCHIO, R. et al. Influence of interhemispheric interactions on motor function in chronic stroke. Annals of Neurology, v. 55, n. 3, p. 400–409, 2004.

NAESER, M. A.; MARTIN, P.I.; NICHOLAS, M. et al. Improved picture naming in chronic aphasia after TMS to part of right Brocar’s area: an open protocol study.

Brain lang, v. 93, p. 95-105, 2005.

NAIR, D. G.; HUTCHINSON, S.; FREGNI, F. et al. Imaging correlates of motor recovery from cerebral infarction and their physiological significance in well- recovered patients. Neuroimage, v. 34, p. 253-263, 2007

NAKAYAMA, H.; JORGENSEN, H.S.; RAASCHOU, H.O. et al. Recovery of upper extremity function in stroke subjects: the Copenhagen Stroke Study. Arch. Phys.

Med. Rehabil, v. 75, p. 394-398, 1994.

NICKOLLS, P.; COLLINS, D.F.; GORMAN, R.G. et al. Forces consistent with plateau-like behavior of spinal neurons evoked in patients with spinal cord injuries.

Brain, v.127, n. 3, p. 660-70, 2004.

NIELSEN, J.; PETERSEN, N.; CRONE, C. Changes in transmission across synapses of Ia afferents in spastic patients. Brain, v. 118, p. 995–1004, 1995 NIELSEN, J. B.; CRONE, C.; HULTBORN, H. The spinal pathophysiology of spasticity — from a basic science point of view. Acta Physiology, v. 189, p. 171– 180, 2007

NOWAK, D. A.; GREFKES, C.; AMELI, M. et al. Brain Stimulation to Enhance Recovery of Function of the Affected Hand. Neurorehabil Neural Repair, v.13, n. 7, p. 641-656, 2009.

PALMIERI, R. M.; INGERSOLL, C. D.; HOFFMAN, M. A. The Hoffmann Reflex: Methodologic Considerations and Applications for Use in Sports Medicine and Athletic Training Research. Journal of Athletic Training, v.39(3), p.268–277, 2004. PASCUAL-LEONE, A.; COHEN, L. G.; HALLET, M. Cortical map plasticity in humans. Trends Neurosci, n. 15, v. 1, p. 13-14, 1992.

PASCUAL-LEONE, A.; TORMOS, J.M.; KEENAN, J. et al. Study and modulation of human cortical excitability with transcranial magnetic stimulation. J. clin.

neurophysiol, v. 15, n. 4, p. 333-343, 1998.

PASCUAL-LEONE, A. Handbook of transcranial magnetic stimulation. London - New York: Arnold - Oxford University Press, 2002.

PASCUAL-LEONE, A.; VALLS-SOLE, J.; BRASIL-NETO, J.P. et al. Akinesia in Parkinson’s disease. II. Effects of subthreshold repetitive transcranial motor cortex stimulation. Neurology, v. 44, p. 892-8, 1994.

PASSARD, A.; ATTAL, N.; BENADHIRA, R. et al. Effects of unilateral repetitive transcranial magnetic stimulation of the motor cortex on chronic widespread pain in fibromyalgia. Brain, v. 130, p. 2661-2670, 2007.

PEPPEN, V.; KWAKKEL,G.; WOOD-DAUPHINEE, S. et al. The impact of physical therapy on functional outcomes after stroke: what's the evidence? Clin Rehabilv. 18, n. 8, p. 833-862, 2004.

PIERROT-DESEILLIGNY, E.; BURKE, D. The Circuitry of the Human Spinal Cord:

Its Role in Motor Control and Movement Disorders, Cambridge:

University Press, 2005.

PORTAL DA SAÚDE DO SUS. Ministério da saúde. Brasília, 2012. http://portalsaude.saude.gov.br/portalsaude/noticia/7920/893/avc:-governo-alerta- para-principal-causa-de-mortes.html. Acessado em 29 Jan. 2013.

REKTOROVA, I.; MEGOVA, S.; REKTOR, B. I. Cognitive functioning after repetitive transcranial magnetic stimulation in patients with cerebrovascular disease without dementia: a pilot study of seven patients. J. neurol sci., v. 229-230, p. 157-161, 2005.

RIDDING, M. C.; ROTHWELL, J. C. Is there a future for therapeutic use of transcranial magnetic stimulation? Nature Reviews Neuroscience, v. 8, p. 559-567, 2007.

RIZZO, M.; HADJIMICHAEL, O.; PREININGEROVA, J. et al. Prevalence and treatment of spasticity reported by multiple sclerosis patients. Mult Scler, v.10, p. 589-85, 2004.

ROSSINI, P. M.; ROSSI, S. Clinical applications of motor evoked potentials.

SCHABRUN, S. M.; CHIPCHASE, L. S. Priming the brain to learn: The future of therapy? Manual Therapy, v. 17, p.184-186, 2012.

SOLE-PADULLÉS, C.; BARTERS-FAZ, D.; JUNQUE, C. et al. Repetitive transcranial magnetic stimulationeffects on brain function and cognition among elders with memory dysfunction: a randomized sham controlled study. Cerebral cortex, v.16, p. 1487-1493, 2006.

SOMMERFELD, D. K.; EEK, E. U.; SVENSSON, A. K. et al. Spasticity after stroke:Its occurrence and association with motor impairments andactivity limitations. Stroke, v. 35, p. 134–139, 2004.

SIEBNER, H. R.; MENTSCHEL, C.; AUER, C. et al. Repetitive transcranial magnetic stimulation has a beneficial effect on bradykinesia in Parkinson’s disease.

Neuroreport, v. 10, p. 589–94, 1999.

SIMON, O.; YELNIK, A. P. Managing spasticity with drugs. Eur. J. Phys. Rehabil

Med., v. 46, n.3, p. 401-10, 2010.

TAMURA, Y.; OKABE, S.; OHNISHI, T. et al. Effects of 1-Hz repetitive transcranial magnetic stimulation on acute pain induced by capsaicin. Pain, v. 107, p. 107-115, 2004.

TAKEUCHI, N.; IZUMI, S. Maladaptive Plasticity for Motor Recovery after Stroke:Mechanisms and Approaches. Neural Plasticity, v. 2012, n 359728, p. 1-9, 2012.

TAKEUCHI, N.; CHUMA, T.; MATSUO, Y. et al. Repetitive transcranial magnetic stimulation of contralesional primary motor cortex improves hand function after stroke. Stroke, v. 36, p. 2681-2686, 2005.

TASSINARI, C. A.; CINCOTTA, M.; ZACCARA, G. et al. Transcranial magnetic stimulation and epilepsy. Clin. neurophysiol, v. 114, p. 777-798, 2003.

TEIVE, H. A. G.; ZONTA, Z.; KUMAGAIA, Y. Tratamento da espaticidade. Arq.

Neuropsiquiatr., v. 56, n. 4, p. 852-858, 1998.

TEIXEIRA, L. F.; OLNEY, S. J.; BROUWER, B. Mecanismos e medidas da espasticidade. Rev. Fisioter. Univ. Sao Paulo, v. 5, p 4-19, 1998.

TEIXEIRA, M. J.; FONOFF, E. T. Tratamento cirúrgico da espasticidade. Rev. Med.

De São Paulo, v. 83, n. 1-2, p.17-27, 2004.

TERAO, Y.; UGAWA, Y. Basic mechanisms of TMS. J. Clin. Neurophysiol., v. 19, p. 322–343, 2002.

VALERO-CABRE, A.; PASCUAL-LEONE, A. Impact of TMS on the primary motor cortex and associated spinal systems. EEE Eng Med Biol, v. 24, p. 29–35, 2005.

VALLE, A. C.; DIONISIO, K.; PITSKEL, N.B. et al. Low and high-frequency repetitive transcranial magnetic stimulation for the treatment of spasticity. Developmental

Medicine & Child Neurology, v. 49, p. 534–538, 2007.

VIVANCOS-MATELLANO, F.; PASCUAL-PASCUAL, S.I.; NARDI-VILARDAGA, J. et

al. Guía del tratamiento integral de la espasticidad. Rev Neurol, v. 45, n. 6, p. 365-

375, 2007.

WELMER, A. K.; VON-ARBIN, M.; WIDEN-HOLMQVIST. L. et al. Spasticity and its association with functioning and health-related quality of life 18 months after stroke. Cerebrovascular Diseases, v. 21, p. 247–253, 2006.

WORLD HEALTH ORGANIZATION. Stroke, cerebrovascular accident. Disponível em: <http://www.who.int/topics/cerebrovascular_accident/en/>. Acesso em: 28 Jan. 2013.

YEH, C. Y.; CHEN, J. J.; TSAI K. H. Quantitative analysis of ankle hypertonia after prolonged stretch in subjects with stroke. Journal of Neuroscience Methods, v. 137, p. 305–314, 2004.

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