Determinar a área de superfície e tamanaho de poros pelo BET
Elucidar o mecanismo de associação do fármaco na MOF sintetizada através de medida de potencial zeta.
Realizar testes de liberação controlada do fármaco.
Realizar testes de adsorção com outros fármacos e fazer uma comparação da capacidade adsortiva entre esses.
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ANEXO A - FTIR 4000 3500 3000 2500 2000 1500 1000 500 [Zn2(1,3-bdc)(bzim)2] Solvotermal T10 T9 T8 T7 T6 T5 T4
In
te
n
s
ida
d
e
N
o
rma
liz
a
d
a
(
%)
Número de Onda (cm
-1)
Figura 32 - Espectro de Infravermelho de todas as amostras do planejamento fatorial e da amostra
ANEXO B - TGA 100 200 300 400 500 600 700 800 900 0 20 40 60 80 100 Ma ssa ( %) Temperatura (ºC) Referencia (Solvotermal) T11 T10 T8 T6 T5 T4
Figura 33 - TGA das amostras do planejamento e da T10 e a referência solvotermal. TGA das amostras