A genome-wide scan reveals important roles of DNA methylation in human longevity by regulating age-related disease genes.

The RT-qPCR analysis showed increased expression of BCL2L11 in ameloblastomas compared with dental follicles, in agreement with the methylation analysis results, while there was

We hypothesised that genetic variants within genes responsible for maintenance of DNA methylation ( DNMT1 ) and for de novo DNA methylation ( DNMT3B ) alter

DNA copy number variants (CNVs) that alter the copy number of a particular DNA segment in the genome play an important role in human phenotypic variability and disease suscepti-

To test whether the impact of radiation on promoter methylation was consistent with the results of the peripheral blood, Rad23b and DNA-damage-inducible transcript 3 (Ddit3) genes

The main objective of this study is to determine whether DNA methylation patterns are associated with the pathogenesis and development of uterine leiomyomas. To this end, we 1)

In the current study, we sought to identify epigenetically silenced genes in MCL using an initial genome wide screening based on pharmacological reversion of CpG methylation and

Table S2 Significant differentially-methylated CpG sites of current compared to never smokers discovered in F4 and replicated in F3. Displayed are a) the results of the linear

Genes mapping (i.e. the nearest gene locus) to the specific hypomethylated CpGs per tissue regardless of the time point (amnion 2372, muscle 548, adrenal 120, pancreas 175)