Genome-wide DNA methylation patterns and transcription analysis in sheep muscle.

The KRT14 gene DNA methylation analysis was performed using Methylation-Specific PCR (MSP), and the KRT19 gene DNA methylation analysis was performed

The RT-qPCR analysis showed increased expression of BCL2L11 in ameloblastomas compared with dental follicles, in agreement with the methylation analysis results, while there was

We hypothesised that genetic variants within genes responsible for maintenance of DNA methylation ( DNMT1 ) and for de novo DNA methylation ( DNMT3B ) alter

Taken together, these results suggest that elevated expression of H19/IGF2 is caused by a specific chromatin structure that is regulated by the DNA methylation status of IGF2 DMRs

Furthermore, besides considering changes in DNA methylation as mechanisms of disease, the role of epigenetics in general and DNA methylation in particular in

In order to validate the importance of the methylation profile in the regulation of gene expression, the transcription of tumor suppressor genes was performed in two

Table S2 Significant differentially-methylated CpG sites of current compared to never smokers discovered in F4 and replicated in F3. Displayed are a) the results of the linear

With maturating differentiation the degree of methylation of the transcription factor binding sites in DNA isolated from the intermediate cell layers within the enhancer