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Identification of a new genomic hot spot of evolutionary diversification of protein function.

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Academic year: 2017

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Fig 1. RT-PCR analysis of GlyR β RNA splicing. (A) PCR using oligonucleotides spanning the large cytosolic loop between transmembrane domains 3 and 4 revealed an additional band (arrow)
Fig 2. Species-specific alternative RNA splicing of GlyR β exon 9A. (A) The scheme illustrates four alternative splicing patterns regarding novel exon 9A in mice
Fig 3. The exon 9A-3-coding sequence facilitates postsynaptic GlyR localization in the somatodendritic compartment of primary spinal cord neurons
Fig 4. Gephyrin splice variant-specific recruitment of GlyR α1-βE9A-3. (A-E) Images of transfected primary hippocampal neurons show HA-α1-βE9A-3 and EGFP-tagged gephyrin splice variants

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