• Nenhum resultado encontrado

Development of a melanoma therapeutic vaccine candidate by the coencapsulation of melanoma antigen peptides and toll-like receptor ligands as adjuvants into polymeric nanoparticles

N/A
N/A
Protected

Academic year: 2021

Share "Development of a melanoma therapeutic vaccine candidate by the coencapsulation of melanoma antigen peptides and toll-like receptor ligands as adjuvants into polymeric nanoparticles"

Copied!
244
0
0

Texto

Loading

Imagem

Figure  1.1. Recommended primary and adjuvant treatment for melanoma (stage 0 to IV), according to  National Comprehensive Cancer Network (NCCN) guideline, v1.2014
Figure  1.2. Antigen presentation by dendritic cells to T cells. A. Activated DCs presenting  extracellular antigens on MHC class II complexes to CD4 +  T cells induce the differentiation of CD4 + T cells into T helper (Th) 1 or Th2 CD4 +  T cells, dependi
Figure  1.3.  DC  role in T cell activation and DC-T cell synapse. DCs play a major role in  immunosurveillance and immune response initiation, placing a bridge between the innate and the  adaptive branches of the immune system
Figure  1.4. Desired immune response elicited by a therapeutic cancer vaccine.  Cancer vaccines must  target antigens and immunoadjuvants to iDCs either in the skin or in the lymph nodes
+7

Referências

Documentos relacionados

Relativamente aos estudantes do ensino superior encarados na sua globalidade, estudos nacionais e internacionais que contemplam os seus perfis de leitor têm possi- bilitado

Among men and women, the prevalence of chronic diseases (heart attack, hypertension, high blood cholesterol, diabetes, chronic lung disease, cancer, stomach or duodenal

101 meios para obter informações sobre os museus, determinados conteúdos ou eventos, e alguns dos visitantes inquiridos ter referido que a rede social Facebook

Summary of the indings: Children and adolescents should adopt appropriate measures of photoprotection in order to decrease the risk of melanoma and non-melanoma skin

Esta apresenta clusters de HH na área de fronteira com a região Norte (zona de transição com a Amazônia), o que seriam provavelmente zonas de exploração da

Ultrasonic test (Pundit) Evaluate the completeness of the bond between concrete ribs and strengthening steel channels Cover survey Evaluate the density of steel in pre-cast and

A vaginal biopsy showed pigmented malignant neoplasia, with in situ melanoma and focuses of superficial invasion, whose histological diagnosis was pigmented malignant melanoma of

No capítulo 2 trazemos um Memorial (O Ensino de Ciências que Vivi: Memórias e Aprendizados), no qual relatamos alguns momentos da minha trajetória estudantil e