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Molecular structure and dimeric organization of the Notch extracellular domain as revealed by electron microscopy.

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Academic year: 2017

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Figure 1. EM of the NECD. (A) Constructs used of the Drosophila (blue, residues 1–1745) and human (yellow, residues 1–1735) NECDs contained 36-EGF repeats (residues 58–1451, Drosophila and 20–1426, human) followed by 3-LNR motifs (residues 1482–1599, Droso
Figure 2. 3D reconstructions of the NECD. (A) Density maps of the Drosophila NECD corresponding to the averages shown in (B)

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