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SIMÕES R ET AL.

106 REV ASSOC MED BRAS 2016; 62(2):106-107

BERNARDO WM ET AL. BERNARDO WM ET AL. UPDATE ON ZIKA VIRUS INFECTION IN PREGNANCY

UPDATE ON ZIKA VIRUS INFECTION IN PREGNANCY

ACCREDITATION

FELIPE-SILVA A ET AL.

Update on Zika virus infection in pregnancy

A

TUALIZAÇÃO EM INFECÇÃO PELO VÍRUS

Z

IKA NA GRAVIDEZ

RICARDO SIMÕES1,2, RENATA BUZZINI², WANDERLEY BERNARDO2, FLORENTINO CARDOSO², ANTÔNIO SALOMÃO1, GIOVANNI CERRI²

1Federação Brasileira das Associações de Ginecologia e Obstetrícia (Febrasgo) 2Guidelines Project, AMB

http://dx.doi.org/10.1590/1806-9282.62.02.106

1. Which factors may be related to the substantial increase in the number of cases of microcephaly in Brazil?

a. Increased active search for this congenital malfor-mation.

b. Increase in the number of pregnant women traveling to northeastern Brazil.

c. Change in diagnostic criteria.

d. Alternatives a and c are correct.

2. What is the clinical and laboratory method indicat-ed (sensitivity and speciicity) to conirm Zika virus infection within a week of the onset of symptoms? a. Immunoenzymatic assay (ELISA).

b. Plaque-reduction neutralization test (PRNT).

c. Reverse transcriptase technique.

d. Real-time polymerase chain reaction (RT-PCR).

e. Indirect immunofluorescence.

3. Regarding symptoms in pregnant women with suspected Zika virus infection, we know that: a. Most are asymptomatic.

b. Patients can manifest fever, rash and fatigue.

c. Patients may present with purulent conjunctivitis, generalized joint pain, vomiting.

d. Alternatives a and b are correct.

4. What treatments are recommended for people in-fected with Zika virus?

a. Flu vaccine.

b. Analgesic agents, rest and antibiotics.

c. Hydration, rest and non-salicylic analgesic drugs.

d. Saline solution, anti-inflammatory drugs, good nu-trition.

5. Regarding pregnant women diagnosed with Zika virus infection, we know that:

a. Care must be maintained according to conventional prenatal protocol if there are no symptoms, and wait until birth for other assessments.

b. Fetal ultrasounds must be done in series every 3 to 4 weeks, and the newborn should receive complete physical examination with ophthalmologic assess-ment.

c. The patient should be referred for high-risk care at a prenatal service with specialized doctors, and the new-born should be evaluated by measuring the head cir-cumference.

d. Evaluation should be done with frequent ultrasounds and, after birth, the newborn should have a head cir-cumference of less than 34 cm to configure a need for more specific analyses.

A

NSWERS TO CLINICAL SCENARIO

: U

PDATE ON

CESAREAN DELIVERY AND SMALL NEWBORN FOR

GESTATIONAL AGE

[

PUBLISHED IN

RAMB 2016;

62(1)]

1. What is the most important single factor in neonatal mortality, in addition to being a signiicant determi-nant of postnatal mortality and infant morbidity?

Birth weight. (Alternative D)

2. A retrospective study considered in this analysis sug-gested that SGA newborns exposed to labor have in-creased risk of early neonatal death compared with those not subject to labor. But in the same study, a lower risk of death was identiied for what periods?

For the late neonatal and postnatal periods in those born vaginally, regardless of gestational age. (Alter-native A)

3. A retrospective study by Lee HC et al. showed in-consistent results; what was found?

(2)

UPDATE ON ZIKA VIRUS INFECTION IN PREGNANCY

REV ASSOC MED BRAS 2016; 62(2):106-107 107

4. According to Boers KE et al., was there any differ-ence in neonatal mortality and morbidity, as as-sessed by Apgar score, among fetuses born vagi-nally or undergoing elective cesarean delivery?

There was no difference in neonatal mortality and morbidity. (Alternative C)

5. What can we say with regard to mode of delivery of small for gestational age fetuses in order to reduce neonatal and perinatal morbidity and mortality?

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