Interleukin-33 primes mast cells for activation by IgG immune complexes.

A total of 919 genes were upregulated in response to amnion activation including numerous inflammatory genes such cyclooxygenase-2 (COX-2, 44-fold), interleukin 8 (IL-8, 6-fold),

Our results demonstrated that PFE significantly reduced the enhanced mRNA expression and protein production of IL-4, IL-5, IL-13 and GM-CSF in BEAS-2B cell with exposure to

The cellular episodes that occur during the anaphylactic reaction involve the activation of tyrosine-kinases and calcium inflow into mast cells and basophils, resulting in a

As mentioned earlier, the possible effect of IL-10 on the production of, or proliferation of IFN- γ producing cells 11,28 may not be important given the high activation of the

The link between T cell derived IL-5 and eosinophil activation in asthmatic airways is further strengthened by the demon- stration that there is an increased number of α IL-5R

Our recent observations that reduced polyI:C-triggered secretion of IL-8 and TNFa, as well as NF-kB activation and the expression of innate viral sensors in the presence of Tr/E

In addition to a role for Fyn kinase in IL-4- mediated B cell and T cell activation [38,39], we recently showed that Fyn is required for IgE-induced STAT5 activation in mast

PAR-1 activation triggers the production of several inflammatory mediators, including IL-6, IL-8 and MCP-1, and induces cell proliferation through the coupling of receptor activation