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Rethinking Dosing Regimen Selection of Piperaquine for Malaria Chemoprevention: A Simulation Study.

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Table 1. DP weight-based dosing guidelines.
Fig 1. Predicted capillary plasma PQ concentration versus time for various chemoprevention regimens of DP in 1 – 2 year olds weighing  11 kg
Table 2. Predictions related to trough and peak capillary plasma concentration of PQ at steady-state with various chemoprevention regimens of DP in 1 – 2 year olds weighing  11 kg.
Fig 2. Predicted capillary plasma PQ concentration versus time for different doses of weekly chemoprevention regimens of DP without and with a loading dose in 1 – 2 year olds weighing  11 kg
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