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LET 230
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24
4) 5 2 ( $ 1
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( $ 1 ; $,-.
d : ( $ 1 $,-.
e : 5
( $ 1
$,-. f : 12
( $ 1
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4 ,?> @ 30
4) 5 2 ( $ 1
5
( 4 2 >
. 4 % &1 4% &1 A B #A
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0 0 9 0
) $,0-. h (
( E ,
. $,-. i ( =. =. &1 ;B ' ) E&7 F1 6
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.
3 -2
-3 4)5 DNA
! 1! 6
%E' DNA ( #!$ 7 F4l & C&* " )$ 1 7 7
& 5 30 " U!" *%0 7, 10
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LET 230
,7 \ # ! $ #!$ 1
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6 " & 5
A ( *
3
6 0*( Z ) l C * T
%# %E'*
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z " 4
6 7 a z " 2 7 b ( %& $
8 ' E %E'7 ,
XAK * , 7 # 2
6 0V L 9
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) z" 4 7 Qd b ( . " # }" %E'8 ! 9&* ! " F #A DNA
" 0
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,7 #5 5 .
@
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, # # 1(l & 24
40 & 57 % T 10
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8!0 3 >"7 & DNA
6 06 9 )$ 1
.
)$ 1 # 9
7 ( G2
24
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, A DNA %E'
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= )
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Qd b ( .
%E', A* " )$ 1 % \Q" 2( DNA
40 –
24 & 57 % T %&Q" 2 (^ \
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F
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6 6
8 ' 6 9 .
2 -2 7 " % DNA
( 5 % &1 30
>
10 > LET 230
" # $% " % &#' .
$,-. a , b #H M
'
DNA 4 1 ? 9 (. bp
100 .
$,-. a I 1 :
4) 5 ( % &1
9(, J# 7 ' 3
$ 1 I
2 : % &1 24 $ 1 2 ( 4) 5 I
3 : % &1 24
$ 1 ; 9(, J# 7 ' ,) 4) 5 2 ( $ 1
I 4 : 1 9(,
$ 1 I 5 : 2 ( % &1 24
4) 5 $ 1 I
6 :
$ 1 1 9(, J# 7 ' ,) $,-.
b I 1 : ( ( 5 % &1
I 2 : % &1 24 $ 1 2 ( 4) 5 I
3 :
% &1 24
$ 1 1 9(, J# 7 ' ,) 4) 5 2 ( $ 1
I
4 : % &1 40 4) 5 2 ( $ 1 .
3 -% &1 4) 52 ( 2 "5 5K 10
> LET
230 " # $% " % &#' .
$,-. a : L 2 DNA 2 4% &1
#% 9 1 24
4) 5 2 ( $ 1
. $,-. b : L 2 DNA 4% &1 40
4) 5 2 ( $ 1
) 2 7 &. ) E&7 G1
G2
(?) 4 *
.
2 7 % &1 ; $,-.
S $1 . 5 =A 2 "5 5K % &1
#M N ( OP* (
DNA J# 5 #H (#M &Q Q ) 4% &1
2 G1 . .
3 -3
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!
C 7 , & 5 F #A
O " ,7 ( #
? G# + b
)
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( ;
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D 5 C
7
? G#+ _ ? G#+ b , & 5 7
, ,< 10 ,
, ) ", LET
230
$ #!$ 1
7 &< 30 , , , & 5 U!"
6 0?
$
" G Q" 2( R 7
8! 0 C
E b
, *XAK 8 '
@ .#
4 ( 5 % &1 2 7 "? R 2 S?)K =
.
T#U"- V 2 4?W?
)
C
(
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T#U"
)
D
(
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T#U"-)
E
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F
(
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8 $ ! .& "
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G1
C&*! 7
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7 ( 9 5 @ & 3
) $ 1 * @
6 " * @ 3 7 0 & < B^\
) * 1T
7 ( $ 1 R* i +A, 6 \
G1
( .
" 7 < B , & ) 7 Q 24 T (
# 0 7
& 7 (* G2
. I$ )$ 1 " ( 7 *! 7 *+" G
O " )\
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, & [ R 7 (*
G2
.
3 -4
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LET
, - ( #!
(RBE) + !"4 $ M , & 5
X , ) "
7 V
,7 ( # " O C "
6 0*+" G .
8!0 5 Q d a
*E LET 9 + !"4 $ M & 5 .
2 Q"2 ( + !"4 $ M LET
" Q"2 (
LET A 230
A 2 * $ #!$ 1
6 %
"2( 7 Q
LET G " * " Q
L 7
* 9 % 1 8 !9& " &
$ 1 O
. ; *E
LET
V + !"4 $ M , & 5
7 O
,7 # ) 90
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10
6 7 R
( , & 5
6 0*+" G , ) " U!" .
5
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LET J#Y?1
RBE
R \
4% &1
2 "# 2 7 "? .
$,-. a : 2 7 "? R $,-.
b :
$1 2 "# R .
J ' )
C
( )
D
(
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H
( J)K )
E
(
$1 ( OP*
.
8!0 6
yE *E
i +A* A "[
LET
, @ , & 5
* 6 06 9
b
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) +' )0
0 .
C 8!0
9
* LET 7 Q , & 5 300
` " $ #!$ 1
yE+ * A
* A * " \
* [
67 5 $
10
@> # !
. "
6 0 * C G
$ 1 *#+ 67 *+" G 130
> # !
1 @yE
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( *
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7 , ) "
* A *#+
F 1 ,
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7 ,7 ( # " O 6 " & 5 )$ 1
.
6
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9 :" U 2 7 "? R [() #H
LET J#Y?1
. ) 5 )
+ ( J ' )
C
( )
D
(
> K )
H
( J)K )
E
(
OP* 4 31 W V
( ( > .
4
-3 4
5 )6 7) .
cd9 ,
$ 1 R 3 R =@
5V & 2 " , ) " %$ E
, %# 0 ,
! , )# + DNA $ 1
, )# +!0
* ] 15 16 [
1 8 ! 9& " & 7 ;
6 " & 5, )$ 1
R ? ) *=d9 `" %
& 5 , ] 17 19 [
*#( V L
. GC& %$ E G
@
* , )# +!0 [ #9
DNA 7
O
$ 1 " G *E
LET & 5
* #( V L
. }" #
9
8 A* $ 1 % \ $ 1 O 7
" )$ 1 6 " ^ , )$ 1
DNA +!0 #* 6 0
#+ ? &8 ' _ 1% DNA
6 " ^ .
8 $
" 0 " 5 " &V T
* #( " +!0, 7 6
DNA 7
+!08C
I 7 %
0 8 $ 22
7 % T
& 5 ]
16 [ . * "
! " 7 7
, # "
6 0V L [ * A )$ 1 & 5V
A ` " *
\ % cd9
%# R
7 ] 4 3 [ .
R $ 1
@
8 C )$ 1 ) "
, 7
DNA , ) " T
LET
G '* <
"
@,4 7 , "7
@ 8 C TV
" \ " I
. " & 5 " & 5
LET <
R 7 V
DNA +!0
,
*
^ hB R %& 1%
6 " , 7
DNA ? &V L R
, ) % " &8 '
. " & 5 & !"2 ( R =@ G GA
LET
2 * 6 0^\ , ) " <
#A $ 1 ? &
* & R
m @l" 0 8 '
#+ ? & 0 " &8 '2
] 18 19 [ .
1 @ %$ E
?+ ! W2\
O $ 1 * " )$ 1
%# R 3
O 1 E *#( V L #+
? +G& " 37 % 6 06 & 5, )$ 1 $ 1
`"8' A "
V 0 , & 57 % $ 1 ? +G&
& 57 % $ 1 ? +G&~ ,7 # O
O V 0
" ,7 ( # 0
] 20 [ . 8! 0 4 9
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O L" )\,
,7 ( # " , )$ 1
CHO U !" , & 5 M & C& *
5 %
" & LET
" 5
#( '
V7< .
# ( "
& 5 )$ 1 ? & 1 'Q
LET *+" G < LET
s& " 5 x
7
1 8 !9&}" # & , G "
$ 1 ) 9 9
. *! " F #A
6 0 L" RP 8!0
O P
" ,7 ( # .# & & 57 % ,7 # O
\ 0
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K D 5`" & ,7 ( #
* 3 + $ 1 ^ 7 , " 8!0* .#
,7 # O * $ 9" 7 %$ E
* #+ LET
C $ # + ? * 9 , & 5
6
LET
+ !"4 $ M A # *
) 230
$ #!$ 1
( C 0
) 8!0 5 ( .
O P ' " "
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* #! " <
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) 8! 0 3 (
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