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Natural products as new antimitotic compounds for anticancer drug development

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Academic year: 2019

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Figure 1 - Antimitotic targets and their respective inhibitors as cited in the text. The targets are placed in the illustration according to the cell cycle phase in which they perform their main functions
Table 2 - Cytotoxic selectivity index (SI), which represents the IC 50 for PBMCs/cancer cell lines after 72h of treatment
Figure 2 - Combretastatin A-4 analogs. (A) LASSBio-1586. (B) LASSBio-1920.
Figure 4 - Formation of atypical mitotic spindles in 2,3,9-trimethoxypterocarpan-treated cells

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